|
XB-GENEPAGE-480716
Gene Symbol:
six1
Gene Name: SIX homeobox 1
Synonyms:
XSix1
( Gene Function: homeodomain transcription factor Protein Function
![]()
Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Depending on context, functions as transcriptional repressor or activator. Required f...[+]
Interactants:
Loading ...
Diseases: Disease Ontology:
autosomal dominant nonsyndromic deafness
OMIM:
BRANCHIOOTORENAL SYNDROME 1; BOR1
External Links:
|
|
Xenbase Gene ID
![]() |
XB-GENE-480717 | XB-GENE-480721 | XB-GENE-17345620 | |||||
Gene Symbol | six1 | six1.L | six1.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
![]() |
Version 9.1
![]() |
Version 9.1
![]() |
|||||
CDS |
Gene model
![]() |
Gene model
![]() |
Gene model
![]() |
|||||
Entrez Gene |
100101702
|
398185
|
734994
|
|||||
mRNA |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
|||||
Protein
![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
![]() ![]() ![]() ![]() |
|||||
Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
|
||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
||||||
Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | six1 | six1.L | six1.S | |||||
Orthology ![]() |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
rat |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
Publications | ||||||||
First |
Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein., J Biol Chem 2000 |
|||||||
Most Recent |
Retinoic acid production, regulation, and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification., Development 2021 |
|||||||
All | View All Papers 15 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 19 terms | 11 terms | 8 terms | |||||
PANTHER | six1 | |||||||
KEGG Pathways | K15614 | K15614 | K15614 | |||||
KOG |
[K] Transcription factor SIX and related HOX domain proteins
|
|||||||
Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | six1 | |||||||
Morpholinos | six1 MO1 | six1 MO1 , six1 MO2 | six1 MO1 | |||||
ORFs | six1 ORF1 | MGC130961 ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



