Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (19) GO Terms (131) Nucleotides (115) Proteins (52) Interactants (328) Wiki
XB-GENEPAGE-481046
???displayGene.symbol???:
 stat3

???displayGene.name???: 
signal transducer and activator of transcription 3 gene 1

???displayGene.synonyms???
aprf , hies , stat3.1 , Xstat3 ( Nomenclature history )

???displayGene.geneFunction???
intracellular signaling

Protein Function :
Transcription factor that binds to target promoter sequences and activates transcription upon il6st/gp130 stimulation. Mediates ventralization of embryos, at least in part via inhibition of smad2 signa...[+]


InterPro :
STAT TF DNA-bd, p53-like TF DNA-bd, STAT TF alpha, STAT N sf, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
T-cell large granular lymphocyte leukemia [+]

MIM:
HYPER-IgE SYNDROME 1, AUTOSOMAL DOMINANT, WITH RECURRENT INFECTIONS; HIES1 [+]

External Links:
1/2
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info