epb41 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (13)

Interactants (5)

XB-GENEPAGE-481624

Gene Symbol: epb41 Gene Name: erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) Synonyms: cytoskeletal protein 4.1, 4.1R, protein 4.1 Add Xenopus synonyms Gene Function: red blood cell cytoskeletal protein binding Interactants: numa1(2) , egf(1) , hnrpdl(1) , slc7a5(1) , tuba4b(1) , View All

XB-GENE-481625

XB-GENE-865471

Molecules		tropicalis	laevis
Gene		JGI XT Genome 4.1 Ensembl
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >CR762249\|Xenopus tropicalis finished cDNA, clone TGas125l23 CGGGAAGCCGGTAGCAGACCCGAAATACGGTAACAATGACAACAGAGAAGGGATTATTGGCTGAGGCAGAAAGTCCTCCTCAGGACCAAAAGCAAGAAGCAGAGGAGGAGGTAGAAGGTTGTACAACTCAACCAGTTGGTAGCAGTTGTGATAAGGATCCAGAGACCGAACAGTCACAAGATTCACCTTCCACCACCTCTCCAAGCACGCGCAAGATCAAGGATCGACATTCAGAAGGAAAGGGCCTCTCTCGCCTTTTTTCCTCTTTCCTGAAGAAACCCAAGTCCCAGGTGTCTTCTGATGAAAAGGAGGTTGAACTGTTGGAGGAAAAGGGACAAGACCAGAAGGATGTTGATGAGGGTTTGGGAGAGCAGCTAGAGGATGATGTTTTTCTGAAGGCCCCTATTGCAGCTCCAGAGCCTGAACTACGAACTGACCCTTCACTAGACCTTCATTCCTTAAGTAGTGCAGAAACCCAGCCAGCTCAAGAGGAACAAAAAGAAGACCAAGACCCAGAAGCAGATTGTGAGGACGTGGAAGGAAAGGAGCAGATAAAAAAACCTGAAGGAGAGTCAAAGGCCTCACAGAAAGTAGTTAGGCGTTCTACCAACATGCACTGCAAAGTCACACTTCTCGATGACACTGTTTATGAGTGTGACTTGGAGAAACATGCAAAGGGTCAGGACTTATTTAAAAAAGTATGCAGCCATCTTAATATTCTGGAGGAAGATTATTTTGGATTGGCATTGTGGGAATCTCCAACTTGCAAGGTCTGGCTTGATCCTTTGAAGGACATGAGGAAGCAGGTTCATGGAGGTCCATGTGAATTCACTTTCAATGTGAAGTTTTATCCCCCAGATCCTGCACAATTGTCAGAGGACATTACCAGGTACTACCTGTGTCTCCAGCTACGCAAAGATATTTTCAGTGGGTGTCTTCCCTGCTCATTTGCCACTCTTGCTCTGCTTGGTTCTTATACTGTTCAGTCAGAAGTGGGTGACTATGAAGAGGATCTTCATGGTGTAGACTATGTTAACGAATTTAAACTCAGTCCGAATCAGACTAAAGATCTTGAGGAGAAGGTTGTAGAGCTTCACAAGTCATACAGATCTATGACACCTGCTCAGGCTGACCTGGAATTCCTGGAGAATGCAAAAAAGCTTACCATGTATGGTGTAGATATTCACCAAGCCAAGGACTTAGAGGGAGTGGATATCAAACTTGGTGTTTGCTCTGGTGGTCTTATGGTCTTCAAAGACAATCTGAGGATTAACAGGTTTCCGTGGCCCAAAGTACTGAAGATCTCATATAAAAGAAGTAGTTTCTTCATCAAAATCCGCCCAGGAGAGCAGGAGCAATATGAAAGTACAATAGGATTTAAGCTTCCCAGCTATAAGGCAGCAAAGAAACTTTGGAAAGTATGTGTGGAACATCATACGTTTTTTAGGTTGACATCCACAGAGTCTATTCCCAAGCATAGGTTTCTCTCTCTAGGATCCAAATTCCGCTACAGTGGGCGCACACAGGCACAGACTCGACATGCCAGTGCTCTTATTGATCGACCTGCTCCCAATTTTGTGCGCACTGGCAGCAAAAGGGCCTCCCGCAGCCTTGATGGAGCTGCAGTTGCAACCCCAGAAGCTTCCAGGAGCCATCGTCCTGTATCAGCCCCAGTCTTCCCTCAGAGAGAAGTCATTACACAGCCTGTGGCCCAAAGAAAGACTCCAGTGCCCAGAGCAGAGGAAATGCCCAAAAAAAAAAAAAAAAAA	Refseq >NM_001087795\|Xenopus laevis erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) (epb41), mRNA CGGGATTTGGGCGCGTCACGTGACGGGAGTTGAAGCGCGGGAAGCTGGTAGCCGACCCGAAATACGGTAACAATGACTACAGAGAAGGGGTTATTAGCTGAAGCAGAAAGCCCTCCTCAGGACCAAAAGCAAGAAGGAGAGGAGGAAGTAGAATCTTGTACAACTCAACCAGTTGTTGGCAGTGGTGATAAGGATCCAGAGACTGAACAGTCACAAGAGTCACCTTCCACTACCTCTCCAAGCACCCGCAAGAGCAAGGACCGACATTCACAGGGAAAGGGCCTCTCTCGCCTCTTTTCCTCTTTCCTGAAGAGACCCAAGTCCCAGGTGTCTTCTGATGAAAAGGAAGTTGAACTGTTGGGGGAAAAGGGACAAGACCAAAAGGATGTTGATGAGGGTTTGGGAGAGCAGCTAGAGGATGATGTTTTTCTAAAGGCCCCTATTGCAGCTCCAGAGCCTGAACTTCGAACTGACCCATCACTAGACCTTCATTCCTTAAGTAGTGCAGAAACCCAGCCAGCACAAGAGGAACAGAAAGAAGACCAAGACCCAGAAGCAGACTGTGAGGACGTGGAAGGCAAGGAACCAATAAAAAAACCTGAAGGAGAATCAAAGGCCTCGCATAAAGTAGTTAGGCGCTCTCCCAACATGCGCTGCAAAGTCACACTTCTCGATGACACTGTTTATGAGTGTGACTTGGAGAAACATGCAAAGGGACAGGACATATTTAAGAAAGTCTGCAGCCACCTTAATATCGTGGAGGAAGATTATTTTGGATTGGCAATATGGGAATCTCCAACTTGCAAGGTCTGGCTTGATCCTTTGAAGGACATCAGGAAGCAGGTTCATGGAGGTCCATGTGAATTCACTTCCAATGTGAAGTTTTATCCCCCTGATCCGGCACAGTTGTCAGAGGATATAACCAGGTACTACCTGTGTCTCCAGCTGCGCAAAGATATTTTCAGTGGGCGTCTTCCATGCTCATTTGCCACCCTTGCTCTGCTCGGTTCTTATACTGTGCAATCAGAGGTGGGTGACTATGAAGAGGATCTCCATGGTGTAGACTATGTCAGTGAATTTAAACTCAGTCCAAATCAAACAAAAGATCTTGAAGAGAAGGTTGGGGAGCTTCATAAGTCATATAGATCTATGACTCCTGCTCAGGCTGACCTGGAATTCCTGGAGAATGCCAAAAAGCTTACCATGTATGGTGTAGATATTCACCAAGCCAAGGACTTGGAGGGAGTGGATATCAAACTTGGGGTTTGCTCTGGTGGTCTTATGGTTTTCAAAGACAATCTGAGGATCAACCGCTTTCCATGGCCCAAAGTACTGAAAATCTCCTATAAAAGAAGTAGTTTCTTCATCAAAATCCGCCCTGGAGAGCAGGAGCAATATGAAAGTACAATAGGATTTAAGCTTCCCAGTTACAAAGCAGCAAAGAAACTTTGGAAAGTATGTGTTGAACATCATACATTTTTCAGGTTGACATCCACAGAGTCTATTCCCAAACACAGATTTCTTTCTCTAGGATCCACATTTCGCTACAGTGGGCGCACACAGGCACAGACTCGACATGCCAGTGCTCTTATTGATCGACCTGCTCCCCATTTTGTACGCACTGGCAGCAAACGGGCCTCTCGCAGTCTTGATGGAGCTGCAGTTGCAACCCCAGAAGCCTCCAGGACCCACCGCCCTGTATCAGCCCCGGTCTTCCCACCGGAATTCCCTGCGGTCCAAAGAAAGACTCCAGGGCCAAGAGTAGAGGAAATGCCCAAAAAGACAGAGGAGAAGCCCAAAGAAGGGATGCCAAATCAGCGGGAAAGTCCTAAGGATGTTAAAGCTACACAGCAAGATTCTCCTTCACCTACTGTCAATGGGGATAAAGTTAAGGACCTGGAAAAGACACAGGACGAGATCATCAGACACCATGCTAGCATCCGTGAGTTGAAGAAGAGTTTCATGGAGTCTGTGCCAGCACCCCGGCCCAGCGAATGGGACAAACGACTTTCTACCCACTCCCCTTTCCGTACTCTCAGCTTTAATGGCCAGGTCCAGACTGGGACAGATGGGCCTCCACTAGTGAAAACACAGACCGTCACCATCTCCAATGCAACAAACGGTGAAAAGGGAGAGATTCCAACTAAGGAGGTTCCCTTGGTACACACTGAGACCAAAACAATCACATACGAAGCAGCCAGATCTGATGATGTTAACACTGACCAGGAACCTGGCATTCTACTAACCGCTCATACAATCACTTCTGAGACCACAAGTAGTACCACCACCACCCAGATCACAAAGACTGTAAAAGGTGGCATCTCAGAGACACTCATAGAGAAAAGGATAGTCATCACAGGAGATGGAGACCTTGATCATGACCAGGTCTTAGTTCAAGCTATTAAAGAAGCAAAGGAGCAGCACCCAGACATGTCTGTTACCAAGGGTGTTGTTCATCAAGAGACAGAAATAGCTTAAGAATACCAGGAGGCGGCACAGACTTTTAACAGGACACATTAAAGACTTTCCAGAAAACCAGCAGTTCCCTGAAGTATCCTCCCTCACCCCTGGGACATTGTCAGCAGCCACTGGAATTTTCTCTCTCTGTTTTCACCTCAACCACAACAATCCACATTTCTGTGTTTGATCAAAGACTGTCTCCCCCTCGAACATGGAATTTACAATGTGACGCCACAACTGTAAACTCCTTCAAAAACTAATGTTGAAATGAAATGGCTTCCCATATCAGAATGAATTC
Protein		NCBI Protein >CAL49376\|erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) [Xenopus tropicalis] MTTEKGLLAEAESPPQDQKQEAEEEVEGCTTQPVGSSCDKDPETEQSQDSPSTTSPSTRKIKDRHSEGKGLSRLFSSFLKKPKSQVSSDEKEVELLEEKGQDQKDVDEGLGEQLEDDVFLKAPIAAPEPELRTDPSLDLHSLSSAETQPAQEEQKEDQDPEADCEDVEGKEQIKKPEGESKASQKVVRRSTNMHCKVTLLDDTVYECDLEKHAKGQDLFKKVCSHLNILEEDYFGLALWESPTCKVWLDPLKDMRKQVHGGPCEFTFNVKFYPPDPAQLSEDITRYYLCLQLRKDIFSGCLPCSFATLALLGSYTVQSEVGDYEEDLHGVDYVNEFKLSPNQTKDLEEKVVELHKSYRSMTPAQADLEFLENAKKLTMYGVDIHQAKDLEGVDIKLGVCSGGLMVFKDNLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYKAAKKLWKVCVEHHTFFRLTSTESIPKHRFLSLGSKFRYSGRTQAQTRHASALIDRPAPNFVRTGSKRASRSLDGAAVATPEASRSHRPVSAPVFPQREVITQPVAQRKTPVPRAEEMP	Refseq >NP_001081264\|cytoskeletal protein 4.1 [Xenopus laevis] MTTEKGLLAEAESPPQDQKQEGEEEVESCTTQPVVGSGDKDPETEQSQESPSTTSPSTRKSKDRHSQGKGLSRLFSSFLKRPKSQVSSDEKEVELLGEKGQDQKDVDEGLGEQLEDDVFLKAPIAAPEPELRTDPSLDLHSLSSAETQPAQEEQKEDQDPEADCEDVEGKEPIKKPEGESKASHKVVRRSPNMRCKVTLLDDTVYECDLEKHAKGQDIFKKVCSHLNIVEEDYFGLAIWESPTCKVWLDPLKDIRKQVHGGPCEFTSNVKFYPPDPAQLSEDITRYYLCLQLRKDIFSGRLPCSFATLALLGSYTVQSEVGDYEEDLHGVDYVSEFKLSPNQTKDLEEKVGELHKSYRSMTPAQADLEFLENAKKLTMYGVDIHQAKDLEGVDIKLGVCSGGLMVFKDNLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYKAAKKLWKVCVEHHTFFRLTSTESIPKHRFLSLGSTFRYSGRTQAQTRHASALIDRPAPHFVRTGSKRASRSLDGAAVATPEASRTHRPVSAPVFPPEFPAVQRKTPGPRVEEMPKKTEEKPKEGMPNQRESPKDVKATQQDSPSPTVNGDKVKDLEKTQDEIIRHHASIRELKKSFMESVPAPRPSEWDKRLSTHSPFRTLSFNGQVQTGTDGPPLVKTQTVTISNATNGEKGEIPTKEVPLVHTETKTITYEAARSDDVNTDQEPGILLTAHTITSETTSSTTTTQITKTVKGGISETLIEKRIVITGDGDLDHDQVLVQAIKEAKEQHPDMSVTKGVVHQETEIA UniProtKB

Genomic

tropicalis

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Synteny

Xenbase G-Browse

GBrowse

Expression		tropicalis	laevis
UniGene		Str.10810	Xl.12931
Gurdon EST/FL			XL481k19ex
Affymetrix 1.0		Str.10810.2.A1_at [+] Str.5594.1.S1_at Str.10810.1.S1_a_at	Xl.691.2.A1_x_at [+] Xl.691.1.S2_at Xl.691.1.S1_at
GEO data			GEO

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene	EPB41	OMIM:611804
mouse		MGI	Epb4.1	All(3) Targeted, other(3)
zebrafish		ZFIN	epb41	4 Lines(s)

Publications
First:		Antisense RNA inhibits expression of membrane skeleton protein 4.1 during embryonic development of Xenopus. [Cell 1988]
Most recent:		Protein 4.1 and its interaction with other cytoskeletal proteins in Xenopus laevis oogenesis. [Eur J Cell Biol 2009]
		View All Papers

Functional Ontologies
GO: Molecular:		actin binding cytoskeletal protein binding prenylated protein tyrosine phosphatase activity More[+] protein tyrosine phosphatase activity structural molecule activity
Biological:		cortical actin cytoskeleton organization and biogenesis
Cellular Component:		cytoplasm cytoskeleton membrane
EC:		protein-tyrosine-phosphatase
KOG:		[R] Erythrocyte membrane protein 4.1 and related proteins of the ERM family

Suppliers		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice	geneservice
		RZPD imagenes	RZPD imagenes

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