Gene Symbol: jun Gene Name: jun proto-oncogene Synonyms: AP-1, c-Jun Add Xenopus synonyms Gene Function: transcriptional activator Interactants: mapk8(44) , mapk1(24) , fos(22) , dvl2(16) , cdkn1a(11) , ins(10) , mapk14(9) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002931588|PREDICTED: Xenopus (Silurana) tropicalis transcription factor AP-1-like (LOC100493911), mRNA TGACCGCTCGCAGATAAGTGTTAGCTGCACGCTGTCCCACAGCCCAGTACAAGTGAGTAGAGCTCACACTGACAGCACTTGTGGCGCTTGGGGAGAAGGAACGTCTAACTTCTCAGTGACTTCTTCCTTGTGTCCGTGTGCCTGACACCTATACTGGGCACACGCACACACCCAGCGCTCGCCATTACATATCTCCGGCGGCGCTTTGGAAACTTTCCCGGGAGTTTATAAGAACTTTTGTGGCGTTCGGAGTACGAGGACCTCTTTGCTGCTAGAGACACAAACACAAAGCTGGTGCTGGTGTCACACTAACGTAAGGTCCAGTCATCGTCCCTGTCCGGCATCCGTTCTATGACTGCAAGGATGGAACCTACTTTCTACGAAGATGCCCTGAGTGCTGCTTTCGCCCAGCACGATGCTACTCCCTATGGTTACAACAAGGTGCTGAAGCAAAGCATGACCCTGAACCTGTCGGACCCCAGCAGCGCCATCAAACCTCACCTGAGAAACAAGGCAGCTGAACTGCTCACCTCCCCTGATGTTGGGCTTCTCAAGCTCGCCTCCCCGGAGTTGGAGAGGCTTATCATCCAGTCCAGCAATGGCATGATTACCACCACCCCGACCCCCACCCAGTTCCTGTGCCCCAAGAATGTCACAGACGAGCAAGAAGGCTTTGCAGAGGGGTTTGTTAGGGCACTGGCAGAACTCCACCATCAAAACAACTTGCCAAGTGTAACCACTGCCACCCAACCTGCCAGCACGGGACTGACACCTGTATCTACTATTGCTGGAAACACTGGCTTCAACAATAGTCTTCACAACGAGCCCCCTGTGTATGCCAATCTAAGTAACTTTAACCCAAGTACCATCACCACATCATCGCCTTTTAACAGCAACACCATGGGGTATACCGGCCAACATCAGAGTAACCCACCAATACCCGTGCAGCACCCCAGGTTACAGGCTCTGAAAGAGGAACCACAGACTGTACCTGAAATGCCTGGGGAGACTCCTCCACTGTCCCCTATTGACATGGAGTCCCAGGAAAGGATAAAGGCTGAAAGGAAGCGTATGAGGAATAGAATCGCAGCATCTAAATGCAGAAAAAGGAAACTGGAGAGGATTTCCAGGTTGGAAGACAAAGTTAAAAACTTAAAATCCCAGAACTCTGAACTGGCATCCACTGCCAACATGCTTAGAGAGCAAGTAGCCCAGCTCAAACAAAAAGTCATGAATCATGTCAACAGTGGGTGTCAGCTAATGTTAACACAGCAGATGCAAACATTCTGAAAAGGCTTCTTTGGGAAAGAGATGTGAGAATTATTTTGTGGAGGGAAATAGTTTCATGTTGAAACTCCCTGGCTCAAAATGAAAGGCACTGAGACCTGACTGTTCTACGTGCGTGTGCGGGGAGTCCTGACAAGCCTTTAGGTGGAGCCTGTGGCAATGCAACAAGCAGTATCACTTGTCAAGTGCTGTTCCTGCTCTAATGAAACATCAGATACATGTTTAACATTGACCAAGACCTGCATGGACCTAACATTCGATGATCATTCAGTATTAAGAAAAGGTTAAACTGCTAGAGACACTAGATTGCTTCCGTAGTTTTCTTACAAAGGGAGGGTGTGGGAGGGAGGCATACGGGACATTGAAAAGTAAAATTAATGACAAATCTGCCTGCCTTCTACATAACTGTGTATGTGTACATATTTGTTTTTTTTATTATAATATTAAGAAAAACTGAATTATTTCAGTAAAATTGCTTCAAGCATTTGTAAGTTATTTTTATGTTTGGGTTAATAAACCCACTACTTTCTGTAAATAAGAGATATTGAGCACTCTTGAGTTTACCATTTGTAATAAAGTATAATAATTTTCTATGTTTTTGTTTCTAAGGACAATTCCAGACGTTCAATTATATTTAAGATATTAAATAAAAGATGTGGAAATTAGATTTTTTTATTTATATTGATATTTTTTTTTACACTGCAATAAACGTGCATGTTAAACTATCTC	Refseq >NM_001090797|Xenopus laevis jun proto-oncogene (jun), mRNA TGAGCTCACACACTGACAGCACTTGTGGAGCTTGGGGAGAAGAACAACTAAGTTCTCAGTGACTTCTTCCTTGCGGCCGGAGCCGTGTGCCTGACAGCGATACTGGCACATACTTATACCCAGCGCTCGCCATTCCCTGTCTCCGGCGGCGCTTCAGAAACTTTCCCAGGAGTTGCTGAGAACTTTTTTGTGGCGTCCGGACTGCGAGGAGCTCTCTGCTGCTAGAGACACAAGCACAAAGCTGACCCGAGGTCCAGTCACCATACCGCTCCCGTATCCGTTGTATGAGCGCAAAGATGGAAACTACTTTCTACGATGATGCCCTGAGCGCTGCCTTCGCCCAGCACGACGCTACTCCCTATGGCTACAACAAGGTGCTGAAGCAGAGCATGACCCTCAACCTGTCCGACCCCAGCAGCGCCATCAAACCTCACCTGAGAAACAAGGCGGCCGAGCTGCTCACTTCTCCTGACGTTGGACTTCTCAAGCTCGCTTCCCCGGAGTTGGAGAGGCTTATCATCCAGTCCAGCAATGGCATGATTACCACCACCCCGACCCCCACCCAGTTCCTCTGCCCCAAGAATGTCACAGACGAGCAGGAAGGCTTTGCAGATGGATTTGTCAGGGCACTGGCAGAACTGCACAACCAAAACACATTGCCAAGTGTTACCACTGCCACCCAACCTGCCAGCACTGGACTGACACCTGCTTCTACTATTGCTATTGCTGGAAACCCTGCCTTCAGCAATACTCTTCACAACGAGCCCCCTGTGTACGCCAATCTAAGTAACTTTAACCCAAGTACCATCAACACCTCAACAGCTTTTAACAGCAACAGCATGGGCTATACAGCCCAACATCATAGCAACCCACCAATGGCAGTGCCGCACCCCAGGCTCCAGGCTCTGAAAGAGGAACCACAGACTGTACCTGAAATGCCTGGGGAGACTCCGCCACTGTCCCCTATTGACATGGAGTCCCAGGAACGGATAAAGGCAGAAAGGAAGCGTATGAGGAATAGAATTGCAGCATCTAAATGCAGAAAGAGGAAGCTGGAGAGGATTTCCAGGTTGGAAGACAAAGTTAAAAACTTAAAATCCCAGAACTCTGAACTGGCATCCACTGCCAACATGCTTAGAGAGCAAGTAGCTCAGCTCAAACAAAAAGTCATGAATCACGTCAACAGTGGCTGTGAGCTAATGTTAACACAGCAGATGCAAACATTCTGAAAAGACTCTTTGGGGGAGAGCTGCTAGGATAATTTTGTGGGGGGAATAGTTTCGATGGTGAAACTCCCTGGCTCAAAATGAAAGGCACTGAGACCTGACTGTTCTACGTGCGTGTGCGGGGAGTCCCTGACAAGCCTTTAGGTGGAGCCTGTGGCAATGCAACAAGCAGTATCACTTGTCAAGTGCTGTTCCTGCTCTAATGAAACATTAGATACGTGTTTAACATTGACCAAGACCTGCATGGACCTAACATTCAACGATCATTCAGTATTAAGTAAAGGTTAAACTGCTAGAGACACTAGGTTGCTTCTGTAGTTTTCTTACAAAGGGAGGGTGTGGGAGGGAGGCATATGGGACATTGAAAAGCAAAAATGAATGACACTTCTGCCTGCCTTCTACATCACTGTATGTGTACATATTTGTTCGTTTTTTTTTTATTATTATTTTAAGAAAACTGAATTATTTCAGTGAAATTGCTTCAAGCATTTGTAAGTTATTTTTATGTTTGGGTTCAAAAACCCACTATTTTCTGTAAATAAGAGATACCGAGCACTCTTGAGTTTACCATTTGTAATAAAGTATAATAATTTTCTATGTTTTTGTTTCTAAGGACAATTCCAGACGTTCAATTCTATTTAAGATATTAAATAAAAGATGTGGAAATTTAGATTTTTTTTTTATTTATATTGATACTTTTTTTTTACAATGCAATAAACATGCATGTTAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002931634|PREDICTED: transcription factor AP-1-like [Xenopus (Silurana) tropicalis] MTARMEPTFYEDALSAAFAQHDATPYGYNKVLKQSMTLNLSDPSSAIKPHLRNKAAELLTSPDVGLLKLASPELERLIIQSSNGMITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHHQNNLPSVTTATQPASTGLTPVSTIAGNTGFNNSLHNEPPVYANLSNFNPSTITTSSPFNSNTMGYTGQHQSNPPIPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERISRLEDKVKNLKSQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQMQTF	Refseq >NP_001084266|jun proto-oncogene [Xenopus laevis] MSAKMETTFYDDALSAAFAQHDATPYGYNKVLKQSMTLNLSDPSSAIKPHLRNKAAELLTSPDVGLLKLASPELERLIIQSSNGMITTTPTPTQFLCPKNVTDEQEGFADGFVRALAELHNQNTLPSVTTATQPASTGLTPASTIAIAGNPAFSNTLHNEPPVYANLSNFNPSTINTSTAFNSNSMGYTAQHHSNPPMAVPHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERISRLEDKVKNLKSQNSELASTANMLREQVAQLKQKVMNHVNSGCELMLTQQMQTF

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.38888	Xl.542
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	JUN
mouse		MGI	Jun	All(12) Targeted, knock Out(3) Targeted, other(8)
zebrafish		ZFIN	jun	1 Lines(s)

Publications
First:		Developmental expression of the Xenopus laevis fos protooncogene. [Cell Growth Differ 1990]
Most recent:		Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. [Development 2013]
		View All Papers 14 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] Transcriptional activator of the JUN family

Reagents		tropicalis	laevis
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.38888.1.S1_at	Xl.542.1.S1_at
Affymetrix 2.0			Xl2.542.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images