casp9 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (18)

Nucleotides (50)

Interactants (39)

XB-GENEPAGE-483801

Gene Symbol: casp9 Gene Name: caspase 9, apoptosis-related cysteine peptidase Synonyms: xCaspase-9, caspase-9, caspase 9, caspase9 Add Xenopus synonyms Gene Function: apoptotic cysteine protease Interactants: apaf1(5) , bcl2(5) , bcl2l1(4) , tp53(4) , amd1(3) , casp3(2) , casp8(2) View All

XB-GENE-483802

XB-GENE-865017

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001123463\|Xenopus (Silurana) tropicalis caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA GATGAGCGGATGACAGCCGGGGAAACAAGAGCTGGGGATGGAGCCGGAATACAGGGACATTCTGAGGCGGAATCGGGTCCGTCTGGTCCAGTCTCTCCAACTTACAGACCTGTGGGATCCACTGCTGCAGAGAGGGATCTTTAGCAATGACATGATAGAGGAGATCCAGAGGGAAGGGACACGGAGGGACCAGGCCAGGAAGCTGCTGATAGAGCTGGAGAGCCGTGGCAGCCAGGCGTTCCCTCTCTTCCTACTGTGTTTAAAGGAGAGCGGGCAGGATAAACTGGCAGATACGCTCCAGTCAGGCAGCGGCGCGTGTGCGTTAGAGCCCATTCCCGTTACCCCAAGCCCGGGGCCGAAACCATTGCCCAAAGCGGATCCTGCTGAATATCCCACAAGAGACGTCCGACGGAAAAAAGAAACACTGGACAAAGACAAGGATTATCCCATGTCCTCTGACCTCAGCGGACTTTGCCTCATTATCAACAACATGAATTTCCACGAATGCACCGGATTATCCAACAGAACAGGGTCAGACGTAGACCGGGACAAACTGGCAAACAGAATGCGCTCCTTTCACTTTGATGTGATGGTGAAGGATAATCTGACTGGGCAGGCCATTCATGATCATCTGGAGGAACTTGCTGCCCAAGACCACAGCCTGAGGGACTGCTGCCTGGTGGTGATCCTGTCACATGGCTGTGAGACCCGGCACATTCAGTTTCCAGGAGGAGTTTACGGAACAGATGGGATTCGAATCCCTGTAGAGAGAATCGTGAGCTACTTTAATGGTTCTAAATGCCCCAGCCTGCGGGGAAAGCCCAAGATCTTCTTCATTCAAGCCTGCGGCGGAGATCAGAAAGACAAAGGATGTTCGGTGACTACTGAGACCCCCCCACTAAGCCCCACTTCAACTTCCCTGCAGTCTGATGCCACCCCTGTTTTTTTCTGGGGAAGACGATAACGACGAAGTGGATGCCGTGTCCAGTATTCCCACTCCCAGTGATATCTTGGTGTCCTATTCCACTTTCCCAGGTTACGTGTCATGGAGGGATAAGCACACTGGATCCTGGTATGTAGAGGTGTTAGACAATGTCCTTGCAGAACATGCAGCAACTGATGACCTACAGTCCCTTCTAGTGATGGTTGCTGACGGAGTTTCAAGCAAAGGAACCTACAAGCAAATCCCTGGATACTTTAACTTCCTGCGGAAGCGTTTTTTCTTTAAAACAGATTGAGTAGCCTATGGGAAGTCAGGTGATAACTTTGTACCAATCACGTGGGTTTCAGTAGGTGGAAGTGTATTCCATCGGCTGGGTTTTTTTATTTACCAAGCAGTCTACTGAATATACTGTGAACTAGAAAATAATCCTTGTGACCGTACCTTTGGGTATAAGAGGCAATTAAAGGGCCAGTAACGATAACAACCTTTTCTTTGGAAGGAAACCCTTATTTTTGACTGCTGGTACCTGTTCTCCCTACACAGCATTAGTGACCTGTCACGGGAAACCCTGCATATAAAAATCTAACGCCTTGCGAAACTAATGCAGAATTTTCAGATTTGATGAATAAGTCAAAATGTGTATATATATTACTTTAATTTATTGGTGTTACTGGCCCTTTAACAAGCCCCTGGGGTGGGGGAGGTTGTCGATGAAAATTCAGTCGTCTCCGGAGCTAGCAATTAAAGGGCTACTAAATGCACAATGGATCCATCAGGGAAATGCTTTTGTAATGATGTGGGTAAATGTCCCTAAGTATAGCGAACCCTTGTCACCCCATCCCTGCACTTTATTGTCTTGTGCTGTCTGCCCAGTGACAGGTTCCTGTGATTTCATTGTCTGTACGATTAGCCTCATAATGATGATAATATTAATAAAGCCCTTTTGCACTTTTGTAACAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001085566\|Xenopus laevis caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA CTCGAGATGGAGCAGGAATTAAGGGATATTTTGAGGCGGAATCGGGTCCGTTTGGTCCAGTCTCTTCAGGTTAAAGAGCTGTGGGATCTCCTGGTGGAGAGAGGAGTCTTCAGCAATGACATGATAGAGGAGATCCAGAGAGAAGGGACACGGAGGGACCAGGCCCGGAAGCTGCTGGTAGAGCTGGAAACACGTGGGAGCCAGGCATTCCCTCTCTTTCTGCTGTGCCTAAAGGAGACTGCTCAGCATGATCTGGCAGATTTCCTCCAATCAGACAGTGGCACACGGGTCTTACAGCCCATTCCAACAACTCCAAGCCCAGTGCTGAAACCTCTACCCAAAGCGGAGCCTGCTGAGTATCCTGCAAGAGAGATCAGAAGTAGAAAAGGAACCCTGGACAAAGACAAGGATTATCCCATGTCATCGGACCCCATTGGATTCTGCCTCATTATTAACAACATGAATTTCCATGAATGCACTGGATTATCCACCAGAACTGGGTCAGACATAGACCGGGACAAGCTGGCCAACAGAATGCGCTCCTTTCACTTTGAGGTCACGGTGAAGGATAATCTGACGGGGCAGGCCATGCATGATCATCTGCAGGCACTTGCTGACCAAGACCACAGCCTGCAGGACTGCTGCCTGGTGGTGATCCTGTCCCATGGCTGTGAGACCCGGCACATTCAGTTCCCAGGAGGGGTTTATGGAACAGATGGAATACGAATTCCCGTAGAGAGAATCGTGAGCTACTTCAATGGTTCCAAATGCCCCAGTCTGCGTGGAAAGCCCAAAATTTTCATCATCCAAGCCTGCGGCGGAGATCAGAAAGACAAAGGATGTGAGGTGACTTCCGAGACCCCACCACTGAGCCCCACTTCAACTTCCCTGCAGTCTGATGCCACCCCTGTTTTCTCTGGGGAAGGTGACAGGGATGAAGTGGATGCTGTGTCCAATATTCCCACTCCCAGTGATATCTTGGTGTCTTATTCCACTTTCCCAGGCTACGTGTCATGGAGGGATAAACACACAGGATCGTGGTATGTAGAGGTGCTGGACAGTGTCCTTGCAGAACATGCAGCTGCAGATGACCTACAGTCCCTTTTAGTGATGGTCGCCGATGGAGTTTCAAGCAAAGGAACCTACAAGCAAATCCCTGGATACTTTAATTTCCTTCGGAAGCGATTTTACTTTAAGACCGATTGAATGCTACATGGGAACTAGGGATGCACCAAATCCAGGATTCGGTTTGGGATACGGCAAGGATTCAACCTTTTTCAGCAGGATTCGGATTCGGCTGAATCCTTCTGCCCAGTCGAACCGAATCTGAATCCTAATTTGCATATGTAAATTAGGTGTGGGAAGGGAAATCACGTGACTTTTTGTCA
Protein		Refseq >NP_001116935\|caspase 9, apoptosis-related cysteine peptidase [Xenopus (Silurana) tropicalis] MEPEYRDILRRNRVRLVQSLQLTDLWDPLLQRGIFSNDMIEEIQREGTRRDQARKLLIELESRGSQAFPLFLLCLKESGQDKLADTLQSGSGACALEPIPVTPSPGPKPLPKADPAEYPTRDVRRKKETLDKDKDYPMSSDLSGLCLIINNMNFHECTGLSNRTGSDVDRDKLANRMRSFHFDVMVKDNLTGQAIHDHLEELAAQDHSLRDCCLVVILSHGCETRHIQFPGGVYGTDGIRIPVERIVSYFNGSKCPSLRGKPKIFFIQACGGDQKDKGCSVTTETPPLSPTSTSLQSDATPVFFWGRR	Refseq >NP_001079035\|caspase 9, apoptosis-related cysteine peptidase [Xenopus laevis] MEQELRDILRRNRVRLVQSLQVKELWDLLVERGVFSNDMIEEIQREGTRRDQARKLLVELETRGSQAFPLFLLCLKETAQHDLADFLQSDSGTRVLQPIPTTPSPVLKPLPKAEPAEYPAREIRSRKGTLDKDKDYPMSSDPIGFCLIINNMNFHECTGLSTRTGSDIDRDKLANRMRSFHFEVTVKDNLTGQAMHDHLQALADQDHSLQDCCLVVILSHGCETRHIQFPGGVYGTDGIRIPVERIVSYFNGSKCPSLRGKPKIFIIQACGGDQKDKGCEVTSETPPLSPTSTSLQSDATPVFSGEGDRDEVDAVSNIPTPSDILVSYSTFPGYVSWRDKHTGSWYVEVLDSVLAEHAAADDLQSLLVMVADGVSSKGTYKQIPGYFNFLRKRFYFKTD

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.28770	Xl.980
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CASP9
mouse		MGI	Casp9	All(4) Targeted, knock Out(2) Targeted, other(2)
zebrafish		ZFIN	casp9

Publications
First:		Apoptosis: checkpoint at the mitochondrial frontier. [Mutat Res 1999]
Most recent:		Acetyl-L-carnitine suppresses thyroid hormone-induced and spontaneous anuran tadpole tail shortening. [Hereditas 2013]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		caspase activity cathepsin F activity cysteine-type endopeptidase activity More[+] magnesium ion binding pyrophosphatase activity
Biological:		metabolic process proteolysis
Cellular Component:
EC:		Cysteine endopeptidases
KOG:		[D] Caspase, apoptotic cysteine protease

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.6657.1.S1_at [+] Str.28770.1.A1_at Str.28770.2.S1_at StrEns.10271.1.S1_s_at	Xl.980.1.S1_at
Affymetrix 2.0			Xl2.980.1.S1_at

Symbol legend[+]