casp9 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (13)

Interactants (24)

XB-GENEPAGE-483801

Gene Symbol: casp9 Gene Name: caspase 9, apoptosis-related cysteine peptidase Synonyms: xCaspase-9, caspase-9, caspase 9 Add Xenopus synonyms Gene Function: apoptotic cysteine protease Interactants: bcl2(5) , apaf1(4) , bcl2l1(4) , amd1(3) , tp53(3) , casp8(2) , abl1(1) View All

XB-GENE-483802

XB-GENE-865017

Molecules		tropicalis	laevis
Gene		JGI XT Genome 4.1 Ensembl
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001123463\|Xenopus (Silurana) tropicalis caspase 9, apoptosis-related cysteine peptidase (casp9), mRNA GATGAGCGGATGACAGCCGGGGAAACAAGAGCTGGGGATGGAGCCGGAATACAGGGACATTCTGAGGCGGAATCGGGTCCGTCTGGTCCAGTCTCTCCAACTTACAGACCTGTGGGATCCACTGCTGCAGAGAGGGATCTTTAGCAATGACATGATAGAGGAGATCCAGAGGGAAGGGACACGGAGGGACCAGGCCAGGAAGCTGCTGATAGAGCTGGAGAGCCGTGGCAGCCAGGCGTTCCCTCTCTTCCTACTGTGTTTAAAGGAGAGCGGGCAGGATAAACTGGCAGATACGCTCCAGTCAGGCAGCGGCGCGTGTGCGTTAGAGCCCATTCCCGTTACCCCAAGCCCGGGGCCGAAACCATTGCCCAAAGCGGATCCTGCTGAATATCCCACAAGAGACGTCCGACGGAAAAAAGAAACACTGGACAAAGACAAGGATTATCCCATGTCCTCTGACCTCAGCGGACTTTGCCTCATTATCAACAACATGAATTTCCACGAATGCACCGGATTATCCAACAGAACAGGGTCAGACGTAGACCGGGACAAACTGGCAAACAGAATGCGCTCCTTTCACTTTGATGTGATGGTGAAGGATAATCTGACTGGGCAGGCCATTCATGATCATCTGGAGGAACTTGCTGCCCAAGACCACAGCCTGAGGGACTGCTGCCTGGTGGTGATCCTGTCACATGGCTGTGAGACCCGGCACATTCAGTTTCCAGGAGGAGTTTACGGAACAGATGGGATTCGAATCCCTGTAGAGAGAATCGTGAGCTACTTTAATGGTTCTAAATGCCCCAGCCTGCGGGGAAAGCCCAAGATCTTCTTCATTCAAGCCTGCGGCGGAGATCAGAAAGACAAAGGATGTTCGGTGACTACTGAGACCCCCCCACTAAGCCCCACTTCAACTTCCCTGCAGTCTGATGCCACCCCTGTTTTTTTCTGGGGAAGACGATAACGACGAAGTGGATGCCGTGTCCAGTATTCCCACTCCCAGTGATATCTTGGTGTCCTATTCCACTTTCCCAGGTTACGTGTCATGGAGGGATAAGCACACTGGATCCTGGTATGTAGAGGTGTTAGACAATGTCCTTGCAGAACATGCAGCAACTGATGACCTACAGTCCCTTCTAGTGATGGTTGCTGACGGAGTTTCAAGCAAAGGAACCTACAAGCAAATCCCTGGATACTTTAACTTCCTGCGGAAGCGTTTTTTCTTTAAAACAGATTGAGTAGCCTATGGGAAGTCAGGTGATAACTTTGTACCAATCACGTGGGTTTCAGTAGGTGGAAGTGTATTCCATCGGCTGGGTTTTTTTATTTACCAAGCAGTCTACTGAATATACTGTGAACTAGAAAATAATCCTTGTGACCGTACCTTTGGGTATAAGAGGCAATTAAAGGGCCAGTAACGATAACAACCTTTTCTTTGGAAGGAAACCCTTATTTTTGACTGCTGGTACCTGTTCTCCCTACACAGCATTAGTGACCTGTCACGGGAAACCCTGCATATAAAAATCTAACGCCTTGCGAAACTAATGCAGAATTTTCAGATTTGATGAATAAGTCAAAATGTGTATATATATTACTTTAATTTATTGGTGTTACTGGCCCTTTAACAAGCCCCTGGGGTGGGGGAGGTTGTCGATGAAAATTCAGTCGTCTCCGGAGCTAGCAATTAAAGGGCTACTAAATGCACAATGGATCCATCAGGGAAATGCTTTTGTAATGATGTGGGTAAATGTCCCTAAGTATAGCGAACCCTTGTCACCCCATCCCTGCACTTTATTGTCTTGTGCTGTCTGCCCAGTGACAGGTTCCTGTGATTTCATTGTCTGTACGATTAGCCTCATAATGATGATAATATTAATAAAGCCCTTTTGCACTTTTGTAACAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001085566\|Xenopus laevis caspase-9 (casp9-A), mRNA CTCGAGATGGAGCAGGAATTAAGGGATATTTTGAGGCGGAATCGGGTCCGTTTGGTCCAGTCTCTTCAGGTTAAAGAGCTGTGGGATCTCCTGGTGGAGAGAGGAGTCTTCAGCAATGACATGATAGAGGAGATCCAGAGAGAAGGGACACGGAGGGACCAGGCCCGGAAGCTGCTGGTAGAGCTGGAAACACGTGGGAGCCAGGCATTCCCTCTCTTTCTGCTGTGCCTAAAGGAGACTGCTCAGCATGATCTGGCAGATTTCCTCCAATCAGACAGTGGCACACGGGTCTTACAGCCCATTCCAACAACTCCAAGCCCAGTGCTGAAACCTCTACCCAAAGCGGAGCCTGCTGAGTATCCTGCAAGAGAGATCAGAAGTAGAAAAGGAACCCTGGACAAAGACAAGGATTATCCCATGTCATCGGACCCCATTGGATTCTGCCTCATTATTAACAACATGAATTTCCATGAATGCACTGGATTATCCACCAGAACTGGGTCAGACATAGACCGGGACAAGCTGGCCAACAGAATGCGCTCCTTTCACTTTGAGGTCACGGTGAAGGATAATCTGACGGGGCAGGCCATGCATGATCATCTGCAGGCACTTGCTGACCAAGACCACAGCCTGCAGGACTGCTGCCTGGTGGTGATCCTGTCCCATGGCTGTGAGACCCGGCACATTCAGTTCCCAGGAGGGGTTTATGGAACAGATGGAATACGAATTCCCGTAGAGAGAATCGTGAGCTACTTCAATGGTTCCAAATGCCCCAGTCTGCGTGGAAAGCCCAAAATTTTCATCATCCAAGCCTGCGGCGGAGATCAGAAAGACAAAGGATGTGAGGTGACTTCCGAGACCCCACCACTGAGCCCCACTTCAACTTCCCTGCAGTCTGATGCCACCCCTGTTTTCTCTGGGGAAGGTGACAGGGATGAAGTGGATGCTGTGTCCAATATTCCCACTCCCAGTGATATCTTGGTGTCTTATTCCACTTTCCCAGGCTACGTGTCATGGAGGGATAAACACACAGGATCGTGGTATGTAGAGGTGCTGGACAGTGTCCTTGCAGAACATGCAGCTGCAGATGACCTACAGTCCCTTTTAGTGATGGTCGCCGATGGAGTTTCAAGCAAAGGAACCTACAAGCAAATCCCTGGATACTTTAATTTCCTTCGGAAGCGATTTTACTTTAAGACCGATTGAATGCTACATGGGAACTAGGGATGCACCAAATCCAGGATTCGGTTTGGGATACGGCAAGGATTCAACCTTTTTCAGCAGGATTCGGATTCGGCTGAATCCTTCTGCCCAGTCGAACCGAATCTGAATCCTAATTTGCATATGTAAATTAGGTGTGGGAAGGGAAATCACGTGACTTTTTGTCA
Protein		Refseq >NP_001116935\|caspase 9, apoptosis-related cysteine peptidase [Xenopus (Silurana) tropicalis] MEPEYRDILRRNRVRLVQSLQLTDLWDPLLQRGIFSNDMIEEIQREGTRRDQARKLLIELESRGSQAFPLFLLCLKESGQDKLADTLQSGSGACALEPIPVTPSPGPKPLPKADPAEYPTRDVRRKKETLDKDKDYPMSSDLSGLCLIINNMNFHECTGLSNRTGSDVDRDKLANRMRSFHFDVMVKDNLTGQAIHDHLEELAAQDHSLRDCCLVVILSHGCETRHIQFPGGVYGTDGIRIPVERIVSYFNGSKCPSLRGKPKIFFIQACGGDQKDKGCSVTTETPPLSPTSTSLQSDATPVFFWGRR	Refseq >NP_001079035\|caspase 9, apoptosis-related cysteine peptidase [Xenopus laevis] MEQELRDILRRNRVRLVQSLQVKELWDLLVERGVFSNDMIEEIQREGTRRDQARKLLVELETRGSQAFPLFLLCLKETAQHDLADFLQSDSGTRVLQPIPTTPSPVLKPLPKAEPAEYPAREIRSRKGTLDKDKDYPMSSDPIGFCLIINNMNFHECTGLSTRTGSDIDRDKLANRMRSFHFEVTVKDNLTGQAMHDHLQALADQDHSLQDCCLVVILSHGCETRHIQFPGGVYGTDGIRIPVERIVSYFNGSKCPSLRGKPKIFIIQACGGDQKDKGCEVTSETPPLSPTSTSLQSDATPVFSGEGDRDEVDAVSNIPTPSDILVSYSTFPGYVSWRDKHTGSWYVEVLDSVLAEHAAADDLQSLLVMVADGVSSKGTYKQIPGYFNFLRKRFYFKTD

Genomic

tropicalis

Genome Browser

Synteny

Xenbase G-Browse

GBrowse

Expression		tropicalis	laevis
UniGene		Str.28770	Xl.980
Gurdon EST/FL			IMAGE:7976131
Affymetrix 1.0		Str.28770.1.A1_at [+] Str.28770.2.S1_at	Xl.980.1.S1_at
GEO data			GEO

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene	CASP9
mouse		MGI	Casp9	All(2) Targeted, knock Out(2)
zebrafish		ZFIN	casp9

Publications
First:		Apoptosis: checkpoint at the mitochondrial frontier. [Mutat Res 1999]
Most recent:		Genome-wide silencing in Drosophila captures conserved apoptotic effectors. [Nature 2009]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		caspase activity cathepsin F activity cysteine-type endopeptidase activity More[+] magnesium ion binding pyrophosphatase activity
Biological:		metabolic process proteolysis
Cellular Component:
EC:		Cysteine endopeptidases
KOG:		[D] Caspase, apoptotic cysteine protease

Suppliers		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice	geneservice
		RZPD imagenes	RZPD imagenes

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