Gene Symbol: myocd Gene Name: myocardin Synonyms: SRF cofactor protein, myocardin Add Xenopus synonyms Gene Function: transcription factor with myb-like domains Interactants: srf(7) , nkx2-5(4) , apcs(3) , gata4(3) , mef2a(3) , mkl1(3) , myf5(3) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002935936|PREDICTED: Xenopus (Silurana) tropicalis myocardin-like (LOC100498057), mRNA ATGCAACTACATGAGACCATTAACACCAACTTTAACCGTCCAGTTACAGAAAAGATCTGTAACCGTGCATGTCATCTTGGAACGTTCAGTAGATCCTTCTCCTCTGGAGACGTGTCGGTAGGGCAGCCGAGGGAACGCTTGATAGCTGATATGTTTCTTCCAACAGTTTTACAGTTACGTCTTCAGCAGAGGAGAAGCCGTGAGCATCTGGTGGACCAAGGACTCATGCCTCCCCTGAAGAACCCCGCTGCATTCCAGGAGCAGAGGAAGAACGTGGACCGAGCCAAGGCTGAAGACTATCTAAAGCACAAGATTAGGAGTCGGCCTGAACTGCTCAACATGCAGATTTTACAAGATCCAGCCAATGAGAGCTCAGCTCAGGCGGCCCACATCAAATTAAAAAGGGCGCGCCTCGCAGATGACCTGAACGAAAGAATCGCTCTTAGACCGGGTCCACTGGAACTGGTGGAGAAGAACATTATTCCTATTGAATCAACTGTGAAAGAGGCCATTAAAGGAAATCAGATGAACTTCTCCAAATCTGTGGATGCCTTTGCCTTTGAAGAGGACAGCAGCAATGATGCCTTGTCTCCAGCAAAGGAGCCGAGCGAGAACCCCCAGGTGCTCAACCAATCTCTCCAGGAGACCAAAGATTTGGAGCCCCTCAACTCCCTTCACTCAGGTCTAACACAGAACCATTCCCAAGAGGTTGATAGCAATGGCCAAGATGGAAGCTCTAGCCAGAGTCACTCCTGTTCTCAGCACTCCGAGGGCCAACTGTCTCCATCTGCGACTGCAACAGTTAAGTCGAAATCACCTGCAGATGTGAAGAACAGGCACAAAAAGCCAAAAGACATTAAACCAAAGGTGAAAAAACTGAAATATCATCAATACATTCCACCTGACCAGAAGGCGGAGAAGTCCCCGCCGCCTATGGACTCGGCTTACGCGAGGCTCCTCCAGCAGCAGCAGTTGTTTCTCCAGCTCCAGATCTTGAGCCAGCAACAGCAGCAGCAACATTTCAGCTACGCCGGGATGCACCACTCCCAGCTCAAGCTTCAAAATGATCAGATTACTCGGAATTCCAACACCTCATCTGTCAACAGTCCTTCCCTGTCTCCGGTGAAGACCACATTTTCAGGACAAGCCAACATCTCTATGAAACCAGGACTGTTGCCTTCAAATCTAGATGATTTAAAAGTCTCTGAATTAAGGCAGCAACTAAGAATAAGAGGTCTACCTGTATCTGGCACGAAGACCTCACTGATGGAGAGATTACGACCTTTCCAAGAATGTGGCGGTAACACAGTTCCGACCTACGGTGAAATTACAACCGTGACTTTTCCAGTTACGCCAAACGGTTCTCTTTCCAGCTACCAAACTCACGCTCCAGCCGGAGTGTTATCCAATGGATTCTATCAGTTTGGCAGCACCAGTTCCACCCCACCCATATCTCCTGCATCATCTGAACTCTCTGTTAATGGATCCTTACCGGATACCTTCAGCGATGGACCAATGTCTTCTCCACCGTTTGTCCTGCACCCGTCCCCAATTCACCTAAGTGCCGAGGAAAGTCTCATGAGCAGCATGAACAGTGGAACTTACCAAGCAGAACTGGAAGGAATGGATGCCGAAAAGGACAAAATGTTGGTAGAGAAACAGAAAGTCATCAACGAGTTGACTTGGAAGCTGAGGCAAGAGCAGAGACAGGTGGAAGAGTTAAGGCTTCAGCTTCAGAAGCGTAAGGGTGACCCCCAAGACAAACAATTTGCATCTCAACACTTTTTTGGCGTACCCATCAAACAGGAAGATGTATCGAGTTGCCCGTTTGCCGCAAAGCAGCTGGCATTGAAAGCACAAGTAAATAACCCAGCTGAAAAACTGGGCGCAGGCAGGGCACAGCCCATCTCTTGCCTGGGGAACAATCACTGCATGGATGCCTCAACCCAAAACTCCATCATGTCTTCCACTTTCTTGAGTCCTCAGTGTTCTCCACAGCACTCGCCACTTGGAACTACTAATAGCCCTCAGCACATAAGTCTGCCCCCATCACCCAATAACCACTATCTGCTGTCGGTATCCCCCAAATCACAAGGAGATAGGTGTAGTGGCTCTCCGAACATTAACAACCGCCTTCACCCAACTCAGGGTGCCGGGAACCCGACTCATTTCCCCCCAAATCCAAACAACCTGCAGGCGCCTTACAGTGAAGCTGAGAAGAAAGGAAACAAGGAGACGGCTCCACCAAAGAGCCCAAAGCAAATTACAAGAAGTCAACAGATGGATGAGCTTCTTGATGTCCTGATTGAAAGTGGAGAAATTCCCGCCAATGCCAAAGATGACCGGCCATGTGCTCAGAAGCATCATCCGTTGAATGTGCCTCCTGGAAACTCAAATCCATCGACTTCAAACGTTCACCTTGCCTACGACAACTGCTCGAGCCACGGTGATGGCCATCTTGAAGTCTTATTAAACTCCCACAGCCCCTTGGGGAGGACCAGTGAACTGCGACTGCTTAAAATCGGGAACGAGGACCCTCAGTTTGAAGGCGTCTTGAGTGGGTTTTCAGGAAAGTCGCCCGAGGAGATTCTTCCCTCTCGAGAAATCTTAGACGCGTCTCTCTCTTCTATGGAAACACAAATGTCCCCTTCGTCTGCAGAAGGTACAGCCATACAGCATCTGAGTTTCACTGAATCCCCTTGGGAGACCATGGAGTGGCTGGATCTGACACCTCCAAGCTCAGCTACTGGCTTGGGATCACTCAGTACCACCGGCCCAAGTATCTTCAACACCGACTTCCTAGATGTTACCGATCTCAATTTAAACACTGCCATGGATCTTCATCTAGAGCACTGGTGATGGACTCAACGGGAGACTTACGCTTGACTTCAATGCAAAACTGAACCCTCAAACATGAATTTATGTAAATGCAATCCAACTGACTGGGCGACAGTTACAATCACTAAAGGCCAAAGGTTCTTCTCATGTTTTCTGATGCCTTTGTGGTATCTGGTGTGGTATCGTCTGTAAAGGAATGCGTGCCAACCTGGATGGCCAAGACTGTATTATAAGGAATCTATATTAATACAATTGTTGTATTACCCTATGGGCATAATTACAGCTCCTTCATCATATTACACTTTTCAGTTTAATTTGGGCATATCTTCTCATTCATGTAGACTTGTTTTGCTATTTCTTGGTCAGTATAACAGGGATTAAAGAAGCCACTATAAGATAAAAGAATTCTACCAGATGAAGACTCCCCCAGAGCTTTTTCAGATTAGGGTCTTCAGGGCTTATTAACTACACTGTAAAAAAAAAACCTTATCTGCCTCTGTCCAAAGCCAGCCTACCTTTCTTGGACTAAACAATGGGTAGGGTAAAGCCCAGAAGACCACCTACTGATGTGCAATCTTTTGTTCACTCATTCACTAGTAGTGTTGGACTGGATCTCC	Refseq >NM_001095601|Xenopus laevis myocardin (myocd), mRNA CTCTGGCTCTTCCTCATGGTTTCACCCAGGGATACACTTTTGTGACATAAACCATTAAACCAGAAAAGCTGGACTTCAGCTCCGCGCCACAACATGACTCTCTTGGGTTCCGAACACTCGCTATTGATCCGGAACAAGTTCAGATCAGTTTTACAGTTACGTCTTCAGCAGAGGAGAAGCCGTGAGCATCTGGTCAGCCAAGGACTCATGCCTCCCCTGAAGAACCCCGCTGCATTCCAGGAGCAGAGGAAGAACGTGGACCGAGCCAAGGCTGAAGACTATCTAAAGCACAAGATTAGAAGCAGGCCTGAAATTCTGAATATGCAAATCTTACAAGATCCAGCTAATGAAAGCTCAGCTCAGGCTGCCCAGATCAAATTAAAAAGGGCACGCCTCGCAGATGACCTGAATGAAAGAATTGCTCTTAGACCAGGGCCACTGGAACTGGTAGAGAAGAACATTATTCCAGTAGAATCAACTGTGAAAGAGGTATTTAAAGGAAATCAGGTCAACTTCTCCAAATCTGTGGATGCCTTTGCTTTTGAAGAGGACAGCAGCAATGATGGTCTGTCTCCAGAAAAGGAGCCAAGCGAGAACTCCCCGGTGCTCAATAAAGCCTCTTTCCAGGAGACCAAAGATTTGGAGACCCTCAACTCCCTTCACTCAGGTCTAACACAGAACCATTCCCAAGAGCATGATAGCGATGCCCAAGATGGAAGCTCTATCCAGAGTCACTCCTGTTCACTGCACTCTGAAAGCCAGCTGTCTCCATCTATGTCCGCAAGTGCGGCAGTTAAGTCGAAATCACCCATAGATGTAAAGAACAGACACAAAAAAACAAAGGATATCAAACCAAAAGTGAAAAAACTGAAATATCACCAATACATTCCACCTGACCAGAAGGCAGAAAAGTCCCCACCGCCTATGGACTCAGCTTATGCAAGGCTCCTTCAGCAACAGCAATTGTTTCTCCAGCTTCAGATCTTGAGTCAACAACAGCAGCAGCAACATTTCGGCTATACAGGGATGCACCACTCCCAGCTCAAGCTTCCAAATGATCTGATTAGGAATTCCAACACATCATCTGTCAACAGTCCCTCCTTGTCTCCAGTGAAAACCACGTTTTCTGGTCAAGCCAATGTCTCTATGAAAGCAGGGCTGTTGCCTTCAAATCTAGATGATTTAAAAGTTTCTGAGTTAAGGCAGCAGTTAAGAATAAGAGGTCTACCTGTGTCTGGTACAAAGACCTCATTGATGGAAAGATTACGACCCTTCCAAGAATGTAGCGGTAACACAGTTCCAACCTACGGTGAAATTACAACAGTGACTTTTCCAGTTACACCAAATGGCACTCTCTCAGGCTACCAATCTCATGCTTCTGCAGGCATGTTATCAAATGGATTCTATCAGTTTGGTAGCACCAGTTCCACCCCACCCATATCTCCTGCATCATCTGATTTTTCTGTTAGTGGATCCTTACCAGATACTTTCAGTGACGGGCCAATGTCTTCTCCACAGTTTGGTTTGCACCCTTCCCCAATTCACCTAAGTGCTGAGGAAAGCCTCATGAATAGCATGAACAGTGGAACTTACCAAGTAGAACTGGAAGGAATTGATGCCGAAAGGGACAAAATGTTGGTAGAGAAACAGAAAGTCATCAACGAGTTGACTTGGAAGCTCAGACATGAACAGAGACAGGTGGAAGAGTTAAGGCTTCAGCTTCAGAAGCGAAAGGTTGACCCTCAAGACAAACAACCTGCATCTCAACACTTTTTTGGGGTACCCATCAAACAGGAAGATGTATCGAGTTGCCCGTTTGCCGCAAAGCAGATGGCGTTGAAAGTACAAGTAAATAACGTAACTGAAAAACTAGGTGTGGGCAGGGCACAGCCCATTACTTGTCTGGTCAACAATCAATGCATGGACGCATCAACCCAAAACTCAATCATGTCATCCACTTTTTTGAGTCCTCAGTGTTCTCCGCAACACTCACCAATGGGAACTACTAACAGCCCCCAGCACATAAGTCTGCCACCTTCACCCAATAACCACTATCTGGCGTCAGTATCCCCCAACTCACAAGGAGACAGGCATAGTGGTTCCCCGAATGTTAACAACCGCCTTCATCCAGCTCAGGCTGCTGGGAGCACGAATCACTTTCCCCCAAATCAAAATAACCTTCCAATATCATACAATGAACAGATTGAGAAAAAAGGAAACAAGGAGACTGCCCCACCGAAAAGCCCAAAGCAAATTACAAGAAGTCAACAGATGGATGAGCTTCTCGATGTCCTAATTGAGAGTGGAGAAATTCCTGCAAATGCCAAAGATGATCGGTCTTGTGCTCAAAAGCATCATCAGTTGAATGTGCCATCTGCAAACTCAAATCCATCGACTTCAAATGTTCACCTTCCCTACGACAACTGCTCAAGCCATGGCGATGGCCATCTTGAAGTCTTACTAAACTCCCACAGCCCCTTGGGGAGGACCAGCGAACTGCGACTGCTTAAAATCGGTAATGACGATCCTCAGTTTGAAAACGTGTTGAGTGGATTTTCAGGAAAGTCGACTGAGGAAATTCTTCCTTCTCGAGAAAACTTAGACGCTTCTCTTTCTTCCATGGAGACACAAATGTCCCCATCATCTGCAGAAGGTACAGCCTTACAACATGTGAGTTTCACAGAATCTCCTTGGGAGACTATGGAGTGGTTAGATTTGACACCTCCAAGCTCAGCTACTTGTTTGAGTTCGCTCACGACTACAGGTCCAAGTATCTTCAACACCGACTTCCTAGATGTTACTGATCTCAATTTAAACACTGCCATGGATCTTCATCTAGAGCACTGGTAAAAGACTCAAATGAAGACTTAAGATTAACCATTGACATCAATGCAAAACGAAACCCTCAAACATGACTTAAAGTAAACCCCATCCAAAGACTGGCCAACAGTTGCAATAACTAAAGACTGATGTTTTTTTAACCTTTCCTCACTTACATGTTTTCTGATGTCTTCATGGTTTTTGCTTCCACACAAAGGAATGTGTGCCAAAGTGGATGCCCAAA
Protein		NCBI Protein >XP_002935982|PREDICTED: myocardin-like [Xenopus (Silurana) tropicalis] MQLHETINTNFNRPVTEKICNRACHLGTFSRSFSSGDVSVGQPRERLIADMFLPTVLQLRLQQRRSREHLVDQGLMPPLKNPAAFQEQRKNVDRAKAEDYLKHKIRSRPELLNMQILQDPANESSAQAAHIKLKRARLADDLNERIALRPGPLELVEKNIIPIESTVKEAIKGNQMNFSKSVDAFAFEEDSSNDALSPAKEPSENPQVLNQSLQETKDLEPLNSLHSGLTQNHSQEVDSNGQDGSSSQSHSCSQHSEGQLSPSATATVKSKSPADVKNRHKKPKDIKPKVKKLKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQHFSYAGMHHSQLKLQNDQITRNSNTSSVNSPSLSPVKTTFSGQANISMKPGLLPSNLDDLKVSELRQQLRIRGLPVSGTKTSLMERLRPFQECGGNTVPTYGEITTVTFPVTPNGSLSSYQTHAPAGVLSNGFYQFGSTSSTPPISPASSELSVNGSLPDTFSDGPMSSPPFVLHPSPIHLSAEESLMSSMNSGTYQAELEGMDAEKDKMLVEKQKVINELTWKLRQEQRQVEELRLQLQKRKGDPQDKQFASQHFFGVPIKQEDVSSCPFAAKQLALKAQVNNPAEKLGAGRAQPISCLGNNHCMDASTQNSIMSSTFLSPQCSPQHSPLGTTNSPQHISLPPSPNNHYLLSVSPKSQGDRCSGSPNINNRLHPTQGAGNPTHFPPNPNNLQAPYSEAEKKGNKETAPPKSPKQITRSQQMDELLDVLIESGEIPANAKDDRPCAQKHHPLNVPPGNSNPSTSNVHLAYDNCSSHGDGHLEVLLNSHSPLGRTSELRLLKIGNEDPQFEGVLSGFSGKSPEEILPSREILDASLSSMETQMSPSSAEGTAIQHLSFTESPWETMEWLDLTPPSSATGLGSLSTTGPSIFNTDFLDVTDLNLNTAMDLHLEHW	Refseq >NP_001089070|myocardin [Xenopus laevis] MTLLGSEHSLLIRNKFRSVLQLRLQQRRSREHLVSQGLMPPLKNPAAFQEQRKNVDRAKAEDYLKHKIRSRPEILNMQILQDPANESSAQAAQIKLKRARLADDLNERIALRPGPLELVEKNIIPVESTVKEVFKGNQVNFSKSVDAFAFEEDSSNDGLSPEKEPSENSPVLNKASFQETKDLETLNSLHSGLTQNHSQEHDSDAQDGSSIQSHSCSLHSESQLSPSMSASAAVKSKSPIDVKNRHKKTKDIKPKVKKLKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQHFGYTGMHHSQLKLPNDLIRNSNTSSVNSPSLSPVKTTFSGQANVSMKAGLLPSNLDDLKVSELRQQLRIRGLPVSGTKTSLMERLRPFQECSGNTVPTYGEITTVTFPVTPNGTLSGYQSHASAGMLSNGFYQFGSTSSTPPISPASSDFSVSGSLPDTFSDGPMSSPQFGLHPSPIHLSAEESLMNSMNSGTYQVELEGIDAERDKMLVEKQKVINELTWKLRHEQRQVEELRLQLQKRKVDPQDKQPASQHFFGVPIKQEDVSSCPFAAKQMALKVQVNNVTEKLGVGRAQPITCLVNNQCMDASTQNSIMSSTFLSPQCSPQHSPMGTTNSPQHISLPPSPNNHYLASVSPNSQGDRHSGSPNVNNRLHPAQAAGSTNHFPPNQNNLPISYNEQIEKKGNKETAPPKSPKQITRSQQMDELLDVLIESGEIPANAKDDRSCAQKHHQLNVPSANSNPSTSNVHLPYDNCSSHGDGHLEVLLNSHSPLGRTSELRLLKIGNDDPQFENVLSGFSGKSTEEILPSRENLDASLSSMETQMSPSSAEGTALQHVSFTESPWETMEWLDLTPPSSATCLSSLTTTGPSIFNTDFLDVTDLNLNTAMDLHLEHW

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.60083 [+] Str.27967	Xl.50383
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	MYOCD
mouse		MGI	Myocd	All(7) Targeted, knock Out(2) Targeted, other(5)
zebrafish

Publications
First:		Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. [Cell 2001]
Most recent:		FoxO genes are dispensable during gastrulation but required for late embryogenesis in Xenopus laevis. [Dev Biol 2010]
		View All Papers 4 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding
Biological:
Cellular Component:
EC:
KOG:		[K] Nuclear receptor coregulator SMRT/SMRTER, contains Myb-like domains

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.27967.2.S1_at [+] Str.27967.1.A1_at
Affymetrix 2.0			Xl2.50383.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images