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Summary Expression Gene Literature (80) Nucleotides (48) Proteins (14) Interactants (350) Wiki
XB-GENEPAGE-485516

Gene Symbol: lef1

Gene Name: lymphoid enhancer-binding factor 1

Synonyms: xlef-1, lef-1, xlef1
Add Xenopus synonyms , Nomenclature history


Gene Function: HMG box transcription factor, wnt signaling

Interactants: tcf3(27) , tcf4(19) , tcf7l1(17) , wnt8a(17) , tcf7(15) , sia1(14) , myc(13) View All

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-485517 XB-GENE-865531
Gene Symbol lef1 lef1
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis
Ensembl Ensembl
UniGene Str.10421 Xl.85523 Xl.58036
RNA-seq profile: Owens, Blitz et al. 2016 lef1
Images 9 expression image(s) for tropicalis and laevis
Data Mining
XenMine lef1 lef1
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LEF1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lef1 MGI, IMPC Ensembl, Eurexpress, MGI
zebrafish
ZFIN lef1 ZFIN Ensembl
chicken
GEISHA LEF1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. [Cell 1996]
Most recent: A Molecular atlas of Xenopus respiratory system development. [Dev Dyn 2015]
View All Papers 14 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding   PANTHER
      Biological: regulation of transcription, DNA-dependent   PANTHER
      Cellular Component: PANTHER
EC:
KOG: [K] Transcription factor TCF-4
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 4 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Morpholino lef1 MO1, lef1 MO2, lef1 MO3, lef1 MO4, lef1 MO5 lef1 MO1, lef1 MO2, lef1 MO3, lef1 MO4, lef1 MO5
Affymetrix 1.0 Str.10421.2.A1_at [+] Xl.410.1.S1_at
Affymetrix 2.0 Xl2.410.1.S1_at

Symbol legend[+]

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