grb10 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (25)

Nucleotides (128)

Interactants (19)

XB-GENEPAGE-485563

Gene Symbol: grb10 Gene Name: growth factor receptor-bound protein 10 Synonyms: rss, irbp, meg1, grb-ir, grb-10 Add Xenopus synonyms Gene Function: signal transduction Interactants: rbp3(18) , rpe(4) , sepn1(4) , grb7(2) , alb(1) , avd(1) , grb14(1) View All

XB-GENE-485564

XB-GENE-865535

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001127409\|Xenopus (Silurana) tropicalis growth factor receptor-bound protein 10 (grb10), mRNA GGAGCAACATGTGCCGCTGCTTGCCCAGTCAGGCACCAGGCACCCAAGGGCCACCTTATAAAGCTGCCACCCTAGCCATGGGCCCTCAGGTGCTTTTATGGATAATGTCGATCAAACGACAGCTTGCTCCCCGAGAGGTCTGGTGGAAACGGGATTCACATCTAAGAGAATATCACTAAACCCTGATGATGATGTTGATCTAGAGGCCCTGGTAAATGATATGAACTCCTCACTGGACAACCTTTACTCCACATGCACCAGTGTCTCTGAATCTGTGCCACTTTTAAAAAATGGTCAGCTTAACAGAAGCCAACTACCAAACTCAGGAACCAACTCTCTTCCGTCCATGCCTCATAAACAGAAGCTTCAGCGTTCCCAACCAATGCATATACATGCAGTCCGGCGTCTCCAAGAGGAACAGCTGCGCACATCATCTTTGCCGGCAATTCCAAATCCATTTCCAGAACTTTGCACTCCAGCCAGTTCACCAGTTCTTGTACCAGGGTCTTTACCTCAAAATCAGCCAGTAGGCAAGAAAAGTGTGGTTAAAGTCTTTAGTGAAGATGGGACAAGCAAAGTGGTGGAAATTCTAGCAGACATGACAGCCAGGGACTTCTGCCAGCTACTGGTTTACCAAAGTCATTGTGTGGATGATAACAGCTGGACGCTAGTGGAGCACCACCCTCACCTAGGATTAGAAAGATGCCTAGAGGATCATGAAATGGTGGTCCATGTACAATCAATGATGTCAAGTGAAAGCAAGTTTCTGTTCAGAAAGAATTATGCAAAATATGAATTTTTTAAGAATCCTGTGAATTTCTTTCCAGAACAGATGGTGGCTTGGTGTCAACAATCAAATGGCAGCATTCCCCAGTCTCAATTACTGCAGAATTTTTTAAATGCCAACAGTTGCCCTGAAATTCAAGGCTTTTTGTATGTAAAGGAGGTGGGGAAGAAATCTTGGAAAAAATTATTTGTGTGTCTGCGACGATCTGGCCTTTACTGCTCCACAAAAGGAATGTCAAAGGAACCAAGGCATTTGCAAGGAATCTCAGACCTAGAAGATAGCAATATTTATTCATTGATAAGCTGCAAGAAACTTTATAATGCGCCAACAGATTTTGGATTTTGTGTCAAGCCCAACAAAGTGAGAAATGAGGTTAAAGAGCTGCGTTTTTTATGTGCAGAAGATGAACAAAGCAGGACTTGTTGGATGACAGCATTCAGGCTTCTCAAGTATGGGATGTTGCTTTATCAAAACTACAGAATTCCACAGCAGAAAAAAAGCTTGCACACAAACTTTTCTACCCCAGTGAGGAGTGTATCAGAAAATTCCTTAGTTGCAATGGATTTCTCTGGGCAGACTGGAAGAGTTATTGAAAATCCAGTAGAAGCACAAAGTGCTGCTATGGAGGAAGGCCATGCTTGGAGGAAACGCAGCTCACGACTGAATGTTCTTGGTAGCCAAAGTCCACTTCATCCTTCCACACTAAGCACAGTAATTCATAGGACACAACATTGGTTTCATGGCAGAATTTCTAGAGAGGAATCGCAAACTATCATTAAGCAACAGGGGCTTGTGGATGGGCTTTTCCTTTTAAGAGACAGCCAGAGCAACCCAAAGGCATTTGTGCTTACACTGTGTCATCACCAGAAAATAAAGCATTTCCAGATTTTACCATGCGAAGATGATGGTCAGCTATTTTTCAGCCTTGATGATGGGAATACCAAATTTATGGATCTAATACAACTTGTTGAGTTTTATCAGCTAAACAAAGGTGTCCTGCCCTGCAAGCTCAAACACCACTGCATTAGAGTGGCCTTATGACCTCAGGCATAGACTATAGGGATGGTCTTGGCTTGGGTGGGAAGAAGGCATGTTTTAACATGCACCTTGTGACTCTGATGTAAGCAGCTGGTGCCAACTCATCATTATTCTCTGGTTTAAAATAGGTCTACAAGGAGTTGTCATGTTCCATTGTCCCCAGTGGCAAAGCTGGGTGTGTTGACTGAAAAAAATTAAGCAAACACCTGCAATCATTTTTAGGCTGGGTTGTTCACCAGTTAAAAGTGTTGATCAATACTGCAAGTTGGGTTGGCTAGAAATGGGAATTAGTTTAGCAAGTGGGTAGGTGTGAATAAGGACTATTGCCCTGGAGTAATCTTGACAATAAAGACTGGTCTGTTTACTTTTTTTATTTTTAAATTGAAATACATTTTGCACTCCTGGATTACGGCCTTTAAAAAAGAGCTGGTGCGGCATTTTTTAATTCATGCAGCAGATAGCTTGCTGTAATGTGTGAATTGCAACAGCCTAAAAGGATTATGGGGAAAAATCAAGATGTTTCTAAGAAGGCTTTGTGCTCCTGTCACCTGCATGTATCTTTCTGAAAGCTCTTCTGGAGATTGGATAAAGCCCTAGATTTCCTCTTACTCTTTACTTACCAATAAGCGAAGTGGCTGTTAAATGTCTGTCCTAATAAGCTTGAGTCTGTAAGTGATAACTATGCATAAATGTTTGAACTACAGTTTTACTCTACCTTAAATACACCTATTGTATTCATCAGGAAATGACATGGTTTTCAGACAAAATATGGTTAAATAGTCACAGGCTGTATTTTTGTGAAACATTTCAATTGTCTACCTAGAGTAACAAATTTTCTTCTCTGTATCCATCATCTGTATATTTTTTTTTCTTTAACAAACACTTCCTTGGTCTAAAGGAAGATAAAATAAATACAGTACTCGTCTGGAAATAGGAATTTAACATACCATGACCGTTTTCTGTGGTCTTGAGCTAAGCTGCTTTTGTGTTTAGTTCTGTCCATAGAAGGGCTATAAAATAGTTAAAAGTCGGGGTTTTGTACCTAGGGATCACTCCTGGTACAAGCAGAAGCTTTAGTGATTCGTATCAGCTGTAATTTCCAACAACAATTTAGAAACACTGTATTCTGGATTAAGGAACACATTCTGTCATACCGTTTTTCATGTAAAGTCTGCATATAAAATGAAGAAACTTGAAAAAAAAAAAAAAAAA	NCBI Nucleotide >BC082224\|Xenopus laevis cDNA clone IMAGE:7204639 GTTATTCTGGCACCTACATCTTTAATGAACAAATGGCTTTATCAGGCTGCCCAGATGCATTCTTACATCCCTACTACCAGGATAATGTTGATCAAACAACGGCTTGCTCACCGAGAGGTCTGGTGGAAACGGGATTCACATCTAAAAGAATATCACTAAATCCAGATGATGATGTTGATCTAGAGGCCCTGGTAAATGATATGAACTCCTCACTGGACAGCCTTTACTCCACATGCAGCAGTGTCTCTGAATCTGTGCCACTTCTAAAAAATGGTCGGTTTAACAGAAGCCAGCTACCAAACTCAGGAACCAACTCTCTTCCGTCCATGCCTCATAAACAGAAGCTTCAGCGCTCCCAACCAATGCATATACATGCAGTCAGGCGTCTCCAAGAGGAACAACTGCGCACATCATCTTTGCCTGCAATCCCAAATCCGTTTCCAGAACTTTGCACTCCAGCCAGTTCACCAGTCCTTGCATCAGGGTCTTTACCTCAAAATCAGCCAGTGGGCAAGAAAAGTGTGGTTAAAGTCTTTAGTGAAGATGGGACAAGCAAAGTGGTGGAGATTCTATCAGACATGACAGCCAGGGACTTCTGCCAGCTACTGGTTTACCAAAGTCATTGTGTGGATGATAACAGCTGGACGCTAGTGGAGCACCACCCTCACCTAGGATTAGGTAGGGGATTATTAAAGAGGATGATCAAGGGGAATAAAACTGCTTTATCACTGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001120881\|growth factor receptor-bound protein 10 [Xenopus (Silurana) tropicalis] MDNVDQTTACSPRGLVETGFTSKRISLNPDDDVDLEALVNDMNSSLDNLYSTCTSVSESVPLLKNGQLNRSQLPNSGTNSLPSMPHKQKLQRSQPMHIHAVRRLQEEQLRTSSLPAIPNPFPELCTPASSPVLVPGSLPQNQPVGKKSVVKVFSEDGTSKVVEILADMTARDFCQLLVYQSHCVDDNSWTLVEHHPHLGLERCLEDHEMVVHVQSMMSSESKFLFRKNYAKYEFFKNPVNFFPEQMVAWCQQSNGSIPQSQLLQNFLNANSCPEIQGFLYVKEVGKKSWKKLFVCLRRSGLYCSTKGMSKEPRHLQGISDLEDSNIYSLISCKKLYNAPTDFGFCVKPNKVRNEVKELRFLCAEDEQSRTCWMTAFRLLKYGMLLYQNYRIPQQKKSLHTNFSTPVRSVSENSLVAMDFSGQTGRVIENPVEAQSAAMEEGHAWRKRSSRLNVLGSQSPLHPSTLSTVIHRTQHWFHGRISREESQTIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKHFQILPCEDDGQLFFSLDDGNTKFMDLIQLVEFYQLNKGVLPCKLKHHCIRVAL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.10026	Xl.73299 [+] Xl.32318 Xl.72050
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		14 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GRB10
mouse		MGI	Grb10	All(7) Gene Trapped(2) Targeted, knock Out(2) Targeted, other(3)
zebrafish		ZFIN ZFIN	grb10a grb10b	3 Lines(s)

Publications
First:		Association of maternal and newly synthesized ribosomes with membranous noncytoskeletal structures in Xenopus laevis embryonic cells. [J Exp Zool 1985]
Most recent:		Cone photoreceptor and Müller cell pericellular matrices are binding domains for Interphotoreceptor Retinoid-Binding Protein (IRBP). [Exp Eye Res 2013]
		View All Papers

Functional Ontologies
GO: Molecular:
Biological:		intracellular signaling cascade signal transduction
Cellular Component:
EC:
KOG:		[T] Growth factor receptor-bound proteins (GRB7, GRB10, GRB14)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.10026.1.A1_at [+] Str.10026.1.A2_at
Affymetrix 2.0			Xl2.49787.1.S1_at [+] Xl2.46863.1.A1_at

Symbol legend[+]