pax2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (93)

Nucleotides (105)

Interactants (380)

XB-GENEPAGE-486800

Gene Symbol: pax2 Gene Name: paired box 2 Synonyms: XPax2, XPax-2, pax-2 Add Xenopus synonyms Gene Function: paired box transcription factor Interactants: pax6(24) , pax8(24) , lhx1(20) , shh(17) , otx2(16) , fgf8(12) , sox2(12) View All	1/5

XB-GENE-486801

XB-GENE-486805

XB-GENE-6256440

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001044423\|Xenopus (Silurana) tropicalis paired box 2 (pax2), mRNA CTAGCACACACATCCCACCTTAAAGTGACAACTCCTGCCGGTCTCTCCATTTTAGGGATATTTTGCAGCCCCCCCCAAACAAATCACACACCCCTGGATTCTTTTTTTCCTCTGCTTTTCGCCTCCTGCTTAACTTTGCGTTGAAGTCAGACAAGTCCAGCCAAAGACTTTGGAGGAAAGCAAACTCACCTTGCACCTTGTGCTGCTGCTCGCCACTGGCTTTTTGCCTCGCTGCCCTACAAGCCTGCTCCAGGAGAGAGCTGTAGTTATGCCATGCACCTGCCGCCCTGAGATTTGCTCCTGTGCCCGGGAAGGCTGCTGAAGGGAACTCGTTCCAAGCTTCCTGACTTGCCTCTGCCTTCGCCCCACGCTGCCCGCACTGCTGCCATTCCTGCCTCCAGCTCCAGCAGCAGAGGGGGAGAGGGGAGTACAGCGCAGCTCAGACCCTCCACCTGATTTTCTTCAAGTCTTGAAGTTCAGTCCAGAGGCGAAACGGCGACTACAGCCGAATTCCTCCCCTTCATTTGCCTCCCCATGGATATGCACTGCAAGGCAGATCCCTTCTCGGCCATGCACCCAGGGCATGGGGGTGTGAACCAGCTCGGGGGGGTATTTGTCAATGGCAGACCCCTACCTGATGTGGTGAGACAGAGGATAGTGGAACTGGCCCATCAAGGAGTGAGACCCTGTGATATTTCCAGGCAGCTGAGGGTCAGCCATGGATGTGTGAGCAAGATCCTGGGCAGGTACTATGAGACGGGGAGCATTAAACCTGGAGTTATTGGCGGATCCAAACCCAAGGTTGCTACTCCCAAGGTTGTCGACAAAATCGCTGAGTACAAGAGACAAAACCCTACAATGTTTGCTTGGGAAATCCGGGACAGGCTTTTGGCTGAAGGAATCTGTGACAATGACACCGTGCCCAGTGTGTCCTCCATAAACAGCAAACAGACTTAAAGCCGCAAATAAGCCAGCCATTCTCGCACGTGTAAAACTGGTCAGGATTACGAGGCGTTTACGTAGGATTCTTCTCGTAACCCAAACTTTGATTGACAAACAGAAAACACTTTGTGAGGAACCCCTTTTCCTGCTTGTTCACTGGCAATTACTGGCTTTAATGGATTAAAAAAAAAAAAAAAAAA	Refseq >NM_001086361\|Xenopus laevis paired box 2 (pax2-a), mRNA AGGGGATAGGGAGTACAGCGCTGCTCATACCCTCCACCTAATTTTCTTCAAATCTTGAAGTTCAGTCCAGAGGCGAAACGGCGACTACAGCCGAATTCCTCCCTTTCATTTGCCTCCCCATGGATATGCACTGCAAGGCAGACCCCTTCTCGGCTATGCACCCAGGGCATGGGGGTGTGAACCAGCTCGGGGGGGTATTTGTCAATGGCAGACCCCTACCTGATGTGGTGAGACAGAGGATAGTGGAACTGGCCCACCAAGGAGTGAGACCCTGTGACATCTCCAGGCAGCTGAGGGTCAGCCATGGATGTGTAAGCAAGATCCTGGGCAGGTACTATGAGACGGGAAGCATTAAACCAGGAGTTATTGGCGGATCCAAACCCAAGGTTGCCACTCCCAAGGTTGTCGACAAAATCGCAGAGTATAAGAGACAAAACCCTACAATGTTTGCTTGGGAAATCCGGGACAGGCTTTTGGCTGAAGGAATCTGCGACAATGACACGGTGCCCAGTGTGTCCTCTATAAACAGAATTATCAGAACGAAAGTCCAACAGCCATTCCATCCAACCCCAGATGGATCTGGAACGCCAGTCGGCACACCCGGGCATACTCTTGTTCCCAGTACAGCATCTCCTCCTGTCTCCAGCGCATCCAATGATCCCGTAGGCTCTTATTCCATTAATGGAATCCTGGGTATTCCTCGTTCTAATGGCGAAAAGAGGAAACGCGATGAAGATGGATCTGATGGTTCTGGTCCAAATGGAGATTCCCAAAGCAGTGTTGAAAGTTTACGGAAACATCTACGGGCTGATAACTTCACCCAGCAGCAACTGGAGGCATTAGATCGAGTCTTTGAGCGTCCTTCTTATCCAGATGTCTTTCAGACTGCTGAGCACATCAAATCTGAACAGGCCAGCGAATACTCCCTTCCAGCGCTTACTCCTGGTCTTGATGAAGTCAAGTCTAGCCTATCAGCATCCGGCAATGCAGACCTAGGAAGCAATGTGTCAGGACCCCAGTCCTACCCTGTAGTAACCGGGCGAGATATGTCAAGCACAACTCTTCCAGGTTATCCACCTCATGTACCTCCAACAGGACAAGGCAGCTACCCTACATCAACTCTTGCTGGAATGGTACCTGGCACCAACGTTTCGGTCCACCATTCGGTCCAACCTGTGGAGTGCTGCTCATGTCTTTCCAGCTCTAAACCATGTCTGTTTCACTGCAGGACTGGGAGTGGGAGTGAATTTTCAGGAAATCCTTACAGCCACCCACAATATACAACCTACAATGAAGCCTGGAGGTTCAGCAACCCAGCACTATTAAGTTCCCCTTATTATTATAGTGCCACATCCAGGGGCTCCGCACCTCCCACTGCTGCCACTGCCTATGACCGCCACTAGTTACCATGGAAACCACATGAAACTACAGGGCGACAACATAGGCCTCCATATTGTACCTGTCTGAACTACATCAACTATGCCATCGGAAGAAGAGTGGCCTACTCTGCTTTCCCTACTGACGTTTCTCAGCTGTAATAAGCTGCTCTTACCTCTGCTGCAAGCCTCTTTGTTGTTATTGTGCACGGTAGCTAGATGAACATCAAGCCAAGTCATCTGATTTCAGAACTTATTTCCAAAAAGGCCCACTATTTAAGTTATGCAGTGGATTGTAGTAGGAAACCACAGAACTCATGTCTTCTCCCTCAAAAAAAGGAATGCGGAATATGAATACCTTTTCTAAGAACAAACATGCGTGCTACAATAAAGAGAGAAAAACTTTTTATGGGCAGCAAATTCAAACTGGAATGGGGAAAAACAGCTATATATATATATAGCGTGTTCCTCAAATGGTGCAAGTAAAAGAGTTTTTACAGAATAATTATGGAACATTTAGCAGTTGGAGGATGGGAAGCTAAAAAAATAGATGTCTTCAATGATGACTCTCGGGAAAACTGCCCACTTTACTTGGACGGGATGCCTCTCTCATATTCTCTCTCCCCATTGAGCTGGCATGTCATGATATTCCACAACGACGCAGTTCCAGTCAAAGCAACAATCAACTCAGAGAAGAAGACAGAAGGACATATTAAAGTCAATCGAATAAACCAAAAAAAAAAAA		NCBI Nucleotide >AF027769\|Xenopus laevis paired-box protein Pax-2 mRNA, partial cds CTTTTGCGCGAAGGAATCTGCGACAATGACACGGTTCCCAGTGTGTCCTCCATAAACAGAATTATCAGGACAAAAGTCAACCAGCCGTTCCATCCAACACCTGATGGA
Protein		Refseq >NP_001037888\|paired box 2 [Xenopus (Silurana) tropicalis] MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINSKQT	Refseq >NP_001079830\|paired box protein Pax-2-A [Xenopus laevis] MDMHCKADPFSAMHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTKVQQPFHPTPDGSGTPVGTPGHTLVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEDGSDGSGPNGDSQSSVESLRKHLRADNFTQQQLEALDRVFERPSYPDVFQTAEHIKSEQASEYSLPALTPGLDEVKSSLSASGNADLGSNVSGPQSYPVVTGRDMSSTTLPGYPPHVPPTGQGSYPTSTLAGMVPGTNVSVHHSVQPVECCSCLSSSKPCLFHCRTGSGSEFSGNPYSHPQYTTYNEAWRFSNPALLSSPYYYSATSRGSAPPTAATAYDRH UniProtKB		NCBI Protein >AAB84188\|paired-box protein Pax-2 [Xenopus laevis] LLREGICDNDTVPSVSSINRIIRTKVNQPFHPTPDG

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.10259 [+] Str.53872	Xl.1130 [+] Xl.85122		Xl.29759
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		81 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PAX2	OMIM:120330
mouse		MGI	Pax2	All(10) Targeted, knock Out(2) Targeted, other(2) Spontaneous(1) Chemically Induced(2)
zebrafish		ZFIN ZFIN	pax2a pax2b	21 Lines(s) 2 Lines(s)

Publications
First:		Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development. [Mech Dev 1997]
Most recent:		HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. [Development 2013]
		View All Papers 27 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:		multicellular organismal development
Cellular Component:		nucleus
EC:
KOG:		[K] Transcription factor PAX2/5/8, contains PAX domain

Reagents		tropicalis	laevis a		laevis b
Clones		EXRC - 1 clone(s)	EXRC - 3 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.10259.1.S1_at [+] StrEns.4662.1.S1_a_at	Xl.1130.7.S1_s_at [+] Xl.1130.5.S1_a_at Xl.1130.2.S1_a_at Xl.1130.8.S1_x_at Xl.1130.1.S1_s_at Xl.8928.1.A1_at
Affymetrix 2.0			Xl2.1130.9.S1_s_at [+] Xl2.1130.9.S1_x_at Xl2.1130.9.S1_a_at Xl2.1130.7.S1_a_at Xl2.1130.4.S1_a_at Xl2.1130.1.S1_at Xl2.1130.3.S1_x_at Xl2.8928.1.A1_at Xl2.8928.1.A1_x_at		Xl2.29759.1.A1_at

Symbol legend[+]