Gene Symbol: fgf2 Gene Name: fibroblast growth factor 2 (basic) Synonyms: HBGF-2, bfgf, fgf-2, basic fgf, xfgf2 Add Xenopus synonyms Gene Function: heparin-binding growth factor Interactants: t(32) , fgf4(21) , fgfr1(20) , fgf1(19) , tgfb1(18) , inhba(17) , bmp4(15) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001017333|Xenopus (Silurana) tropicalis fibroblast growth factor 2 (basic) (fgf2), mRNA CTGCCTGTAAAATACCTCACTGAGGGAAAAGTTTGCCAGCTTTGCAGTTGCAATTGAATGAACTGTGAGGCCCTGAGCAGGGAAAACTGAGGCGACACACAGGGATTTTATCAGATACCACACTGCTACCTGCTAAACCTCGTCTAGGAGAGGCTTCTGGGAAGGCAGGGATGGCAGCAGGAAGCATCACAACCCTACCAACCGAATCTGAGGATGGAAACACTCCTTTCCCACCGGGGAACTTTAAGGACCCCAAGAGGCTCTACTGCAAGAATGGGGGCTACTTCCTCAGGATTAACTCAGACGGGAGAGTGGACGGATCAAGGGATAAAAGTGACTTACACATAAAATTACAGCTACAAGCAGTAGAGCGGGGAGTGGTATCAATAAAGGGAATCACTGCAAATCGCTACCTTGCCATGAAGGAAGATGGGAGATTAACATCGCTGAAGTGTATAACAGATGAATGCTTCTTTTATGAACGATTGGAAGCTAATAACTACAACACTTACCGGTCTCGGAAAAACAACAGCTGGTATGTGGCACTAAAGCGAACTGGGCAGTATAAAAATGGATCGACCACTGGACCAGGACAAAAAGCTATTTTGTTTCTCCCAATGTCAGCAAAAAGCTGATCTGTGATGACTCCCTTTGTAGGTCACCCTTTCTAAGACCAGAAAATACTTTTATATTTGTAATATTAAATGTGAGGCTGAGGTACAGCATTGGTATATTGTATATTTGTGCAGGCTCTTGAGCCAGTTTTTGAGAATGATGAATCCAAAATACAATAGTCCACTCAGTGTTTGATCTGCGTGTGGTATATTGAGTGTTGTACTTGCATTTCTGGGTGAGGAGTCTGGACAGTTTGGATGAAGGTTCTTTGGGGTAGCATGGGATTGGGGCATCATTTGTGGTAGAGGGAGAATTAGAGTGTGAGGCTTGTAGGTGGTTGGCACTTCCTTCATGGGTCTCTGGTGGTTCCTTGTGGTGGGGTGGATGGGGGGGCCCTGGGTGGACAGCTGGGAGTGTTCTCGTGGTTGGGTCCACCAGATGGAAGCCTTCGTTGTGGCCATGGAGTGGAGGCTTGGCGGCTCTGCTTGTTGTGATGGTTGTGTTGCTACGGTGGGCGGGCTCTCGTGGATCCGTCCGTTCACGCTTCGGGCGTTCCTGATGGCAGAGGTTTGTGGTGTGTGGCGGTGGCTTCGGGCGACAGGTGGTGTACGGGTCGGACTTTCCGGGTGCCCCGGGGTGGTTGTGCTGCTGCCTTGTGCTTAATGGGGACTTGGATTCCGGGTGAATGCCGGTCTCTTCGGGGACTTCTCTGGCTGCTGTAGCTCCTACAATTGAGAGAAAAAAAACATTTGCTTTAAGTACAGCAACAGCTTTCCAAAAAACCTTTGCTTTCAAAACAGAATACAGACTGCTTAGTATGCAATTTGTACCAATACATTCTTAGTTCTACTTTTAAGAGGGATTTTTAAAGTGAAAATGATATTACTACACGGCTGTGTAGTACACAAATAGCAAATATTTCATGGTAACAACTATATTTAATAAAGGGCTGTTCAGCTGGAGGGCTGTGTGCTTGACATGGCCCTGTAGGGGATTTTTATGACCCCCCAGTGTATTTTATAAATTTGATCATTATAGTGTAATTTGGTGATCAACATGTGTTTTGAGAAATAATCGGATCATTACATATAAATAAGTTAAACAGTACTGATATTAGATGACAAGAAACCCCCCTCTGCCATTTTTGAAACAGAAGGGGTTATTATTTAGTCTTACTGTATGCTCCCATACAGGTCTTTTTCCTTCCTCCACAGAATCATGAAACACTTACATGTCCTCCATACCTGGCCATAAAATGAAGAGCCTGGGTACTGGATGTGAAGCAGCTAGACATGGTGGCTGGCCACCTTATTTTACTAAATTCTAAGGCCAGGTACAGAGAAAGCGGCAAACTTTGAGGGAGCCCTTGTTGCGGTTTGTTGGAGGAAACGGGGACCTGTGCAAGGGGCACTTTTTCAAAAGCAGTATGTAGGGTTTCCTTGTCCTTTTTATAAACTGAAAAAAGTAAAACCCATTCTGCAATTTCACTTGGTACTGAACATCTTTATGTTGACAGATTTAAGAAGTTGCAGAAATCTACAGGAACTGCCAAACAGAATTGGTTATTTATAATATAAATTAGAATTACTGTTATAAGGAAGGTCATGCACTATTCATCTAGGCTCTCAGTGCTATTGGATGAATAAATATATATTATTATCAGCTATAAATCCTTAATGAACCAAACACCAAAATTAAATGTTGGATAACAAGATTATTGTTATATTTAAATGAAAAAGTATGAACAAATCTATAACACTTACCTGTGTCTTCCCCTTGGTCTGGCAGACCACCGGGAAATTTCCATGCATTTGCTGTCTGTAATAAAAAAAAAAAAAAAAAA	Refseq >NM_001099871|Xenopus laevis fibroblast growth factor 2 (basic) (fgf2), mRNA GAATTCCGTAGCATCTCCTTGCCTGCCCCTGGCTCATGGCTGCTGCTGTTGAACTTTCTCTGCCTTTGAATTACAGGAGATGACAGATTTGCCAAGGGCTGCTGAAAGGTGCTTTTACTGATGCTGCTGAGGCACTGTAGGAGGGCTGCATGTGAATACCTCACAAAGGGAAAAGTTTGTCAGACTTCCAATTGAATGAACTGTGAGGCCCTGAGCAGGGAAACTGAGGCGAGACACAGGGCTATTATCAGAAAACGAACTGCTGCTACCTGTTGGACCTCGCCTGGGCTCTGAGAGGCTGCTGGGAAGGCAGGGCTGAAACATTGTTGCAGGGATGGCGGCAGGGAGCATCACAACTCTGCCAACTGAATCCGAGGATGGGGGAAACACTCCTTTTTCACCAGGGAGTTTTAAAGACCCCAAGAGGCTCTACTGCAAGAACGGGGGCTTCTTCCTCAGGATAAACTCAGACGGGAGAGTGGACGGGTCAAGGGACAAAAGTGACTCGCACATAAAATTACAGCTACAAGCTGTAGAGCGGGGAGTGGTATCAATAAAGGGAATCACTGCAAATCGCTACCTTGCCATGAAGGAAGATGGGAGATTAACATCGCTGAGGTGTATAACAGATGAATGCTTCTTTTTTGAACGACTGGAAGCTAATAACTACAACACTTACCGGTCTCGGAAATACAGCAGCTGGTATGTGGCACTAAAGCGAACCGGGCAGTACAAAAATGGATCGAGCACTGGACCGGGACAAAAAGCTATTTTATTTCTCCCAATGTCCGCAAAGAGCTGATCTGAAATGACTGATTTTTTTAGGTCAAGAGAAACCCTTTCTAAGACCAGAAAATCCTTTTATATCTGTAATATTAAATGTGAGGCTGAGGTACAGCATTGTTTTATTGTATATTTGTGCAGGCTCTTGAGCTAGTGTTTGAGAGTGATGAAACTAAACTACAGTTGTCCACTCAGTATTTAATCTACACGTTAATATATTGAATATTATACATGCATTTCTAAATTAAGTGTCTGGAATTTTTACATGAAAATTCCTTAAATACTATAAAAGTAGAGTACCGTAGTAAAAGGAGAATTAAAATGTGAAGCTT
Protein		Refseq >NP_001017333|fibroblast growth factor 2 (basic) [Xenopus (Silurana) tropicalis] MAAGSITTLPTESEDGNTPFPPGNFKDPKRLYCKNGGYFLRINSDGRVDGSRDKSDLHIKLQLQAVERGVVSIKGITANRYLAMKEDGRLTSLKCITDECFFYERLEANNYNTYRSRKNNSWYVALKRTGQYKNGSTTGPGQKAILFLPMSAKS	Refseq >NP_001093341|heparin-binding growth factor 2 precursor [Xenopus laevis] MAAGSITTLPTESEDGGNTPFSPGSFKDPKRLYCKNGGFFLRINSDGRVDGSRDKSDSHIKLQLQAVERGVVSIKGITANRYLAMKEDGRLTSLRCITDECFFFERLEANNYNTYRSRKYSSWYVALKRTGQYKNGSSTGPGQKAILFLPMSAKS UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.68201	Xl.76214 [+] Xl.34041
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		8 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FGF2
mouse		MGI	Fgf2	All(7) Targeted, knock Out(5) Targeted, other(2)
zebrafish		ZFIN	fgf2

Publications
First:		Mesoderm induction in early Xenopus embryos by heparin-binding growth factors. [Nature 1987]
Most recent:		Xenopus laevis tadpoles can regenerate neural retina lost after physical excision but cannot regenerate photoreceptors lost through targeted ablation. [Invest Ophthalmol Vis Sci 2013]
		View All Papers 9 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		growth factor activity
Biological:
Cellular Component:
EC:
KOG:		[T] Fibroblast growth factor

Reagents		tropicalis	laevis
Clones		EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.20390.1.S1_at [+] Str.20390.1.S2_at	Xl.444.3.A1_at
Affymetrix 2.0			Xl2.444.4.A1_at [+] Xl2.34041.1.A1_at

Symbol legend[+]

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