ran Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

My Xenbase
[Login] [Register]

Search

Summary

Gene Literature (191)

Nucleotides (1434)

Interactants (183)

XB-GENEPAGE-489467

Gene Symbol: ran Gene Name: RAN, member RAS oncogene family Synonyms: ran-1, tc4, gsp1, ara24 Add Xenopus synonyms Gene Function: small GTPase Interactants: rcc1(43) , tpx2(21) , kpnb1(19) , ranbp1(14) , aurka(12) , rangap1(12) , xpo1(12) View All

XB-GENE-489468

XB-GENE-865870

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001004829\|Xenopus (Silurana) tropicalis RAN, member RAS oncogene family (ran), mRNA CCCAGAGCGCGCCCTGCTATTTGAATCCCGCTTCCGCCATTTTCTCTCGCTGCTTTACAGACGCTTCTGGAAGGTGAGATTCTAACCCGTGGGAGATATAGGCTGGGCCCTGCCGCATAATCCGCCCGACATCTCGGCCATCCCTATTCGCAAAGCGTCCCGAAGCTCTTGTAGCACTCGCTGGTTAATCGTGCGGCCGGGCACGGTAGATTTGAGAGGGATTCTAGTCGGCTGACAAACATACCATGGCAGCCCAAGGAGAACCTCAAGTGCAGTTTAAGCTTGTTCTGGTTGGGGATGGTGGTACCGGTAAAACAACCTTTGTGAAACGTCACTTGACTGGTGAATTTGAGAAGAAATATGTAGCCACACTTGGTGTTGAAGTTCATCCCCTGGTTTTCCACACTAACAGAGGGCCAATCAAGTTTAACGTGTGGGATACAGCTGGTCAAGAAAAGTTTGGTGGTCTCAGAGATGGATATTATATCCAGGCCCAGTGTGCCATTATCATGTTTGATGTTACATCAAGAGTCACATACAAGAATGTACCAAACTGGCATAGAGATCTTGTAAGAGTGTGTGAAAACATCCCAATAGTCTTGTGTGGTAATAAAGTGGACATAAAGGACAGAAAAGTTAAAGCCAAATCAATTGTCTTCCATAGGAAGAAGAATCTTCAGTACTATGATATTTCTGCTAAAAGTAACTACAATTTTGAGAAGCCCTTCCTTTGGCTTGCAAGGAAACTTATAGGTGACCCCAATTTTGAGTTTGTAGCCATGCCAGCCCTTGCCCCACCAGAGGTTGTAATGGATCCGGCATTGGCAGCACAGTATGAGCAAGATTTACAGCATGCTCAGGCCACTGCACTGCCAGATGAAGATGATGATCTGTGAGGGGAATGAAGCTGGAGCCCAGCGTCAGAAGTCTAGTTTTATAGGCAACTGTCCTGTGATGTGGTGCAGCGTGTTTGCCACTCTATTATATAGCTGAGCAGAACATGTGCTTAATCTTTTTGGGATGCAGAAGGAGATGAATGGGCTTCGGAGTGAATGTGGCAGTTCAGAAAATAATTCCTTCATATTTTGGACCTGCGTCTTTAGCTGTTTGGGACTGCAAATATTCTACCCTCAAGTTTCAAATCTTAAGTTAAGACTGCTACAGTCACATCACAAAATTCAGTGGTGAATCTTGTTACTGTCATTCCCATACCTTTTTCGTTTAGATCATAATAAAGTTATGTTTCAAATACCTTAGCAAGTTTTCATATGTTACAGATGCCTTAACATGTGATGACATTTATATATTTTTCTTTTAAATGTAAGTCTGAGTTCATAATTATTTTCACTTGTGCTCTTCTCTTGCCAGTTATGCTCCTCCTTTTGTAATGCCACATTGCAATTTGCTGTAGTGAGACCTTCTGTTAGTCTTGCTTTAAAGAATTGGCTAAACCTTTAAAATTCCAAGATATTAAGGGATATATGTGCTATTAATTTGAATAAATGTTGTTATAAAAGGCTGATTTGTTCTTGTTGGGTAGAAAAAAAACATTAGAAACCTCAACTTTTCTTGCATCCACAGTAAAAACATATGTTAATATCTTGGAATTTAAAAAATTAAATTGCAAAAGTGCCTAGAATAGCACTCAGCAATTTTACAGTAAAGGTTTACTTATCCTTTAATGACAACCCCCATCTCCAAATCATTGTGTGCACTGACCCACCCTTATTAAAACAATTTGCTTTATACCAGTGACCCTATTATAAAACCACAATATAATAAAGAAGAAAAACCTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001135075\|Xenopus laevis RAN, member RAS oncogene family (ran), mRNA AGGCTGACAAACTTGCCATGGCAGCCCAAGGAGAACCTCAAGTGCAGTTTAAGCTTGTTCTGGTTGGAGATGGTGGTACCGGTAAAACAACCTTTGTGAAACGTCACTTGACTGGTGAATTTGAAAAGAAATATGTAGCCACACTTGGTGTTGAAGTTCATCCTCTGGTTTTCCATACTAACAGAGGCCCGATCAAATTTAATGTGTGGGATACAGCTGGTCAAGAAAAGTTTGGTGGTCTCAGAGATGGGTATTATATCCAGGCCCAGTGTGCCATTATCATGTTTGATGTAACATCAAGAGTCACATACAAGAATGTACCGAACTGGCATAGAGATCTTGTACGAGTGTGTGAAAACATCCCAATAGTCTTGTGTGGTAACAAGGTGGACATAAAGGACAGAAAAGTTAAAGCCAAATCAATTGTCTTCCACAGGAAGAAGAATCTGCAGTACTATGATATTTCTGCAAAAAGTAACTACAATTTCGAGAAGCCCTTCCTTTGGCTTGCAAGAAAACTTATAGGTGACCCCAATCTTGAGTTTGTAGCCATGCCAGCCCTTGCCCCACCAGAGGTTGTAATGGATCCCGCATTGGCAGCACAGTATGAGCAGGATTTACAGAATGCTCAGGCCACTGCACTGCCAGATGAAGATGATGATCTGTGAGGGGAATGAAGCTGGAGCCCAGCGTCAGAAGTCTAGTTTTATAGGCAACTGTCCTGTGATGTGGTGCAGCGTGTTTGCCACTCTATTATATAGCTGAGCAGAACATGTGCTTAATCTTTTTGGGATGCAGAAGGAGATGAATGGGCTTCGGAGTGAATGTGGCAGTTCAGAAAACAATTCCTTCATATTTTGGACCTGCGTCTTTAGCTGTTTGGGACTGCAAATATTCTACCCTCAAGTTTCAAATCTTAAGTTAAGACTGCTACAGTCACATCACAAAATTCAGTGGTGAATCTTGTTACTGTCATTCCCATACCTTTTTCGTTTAGATCATAATAAAGTTATGTTTCAAATACCTTAGCAAGTTTTCATATGTTACAGATGCCTTAACATGTGGTGAGGTTTATATATTTTTCTCTTAAATGTTAGTTAGTTTATATTTTTCACTTGTGCTTTTCTATTGCCAATTATGCTCCTCCCCCTTTTTAACGCTGCCGTTGCAATCTGCTGTAGCGAGCTCTACTGTTGGTCTTGCTTTAAAGACTAACCCCATCCTCCAAATCATTGTGTGCTCTGTCCCACCCTTATTAAAACAATTTGCTGGGGTTCTTTATACCAGTGCCCCTATTCTAAAACCACAAATCAACATAATAAAGAAAAAAAAAAACCTTGAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001004829\|GTP-binding nuclear protein Ran [Xenopus (Silurana) tropicalis] MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNFEFVAMPALAPPEVVMDPALAAQYEQDLQHAQATALPDEDDDL UniProtKB	Refseq >NP_001128547\|RAN, member RAS oncogene family [Xenopus laevis] MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEQDLQNAQATALPDEDDDL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.47018 [+] Str.44146 Str.45016 Str.60713 Str.79788	Xl.57143
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	RAN
mouse		MGI	Ran	All(2) Targeted, knock Out(1)
zebrafish		ZFIN	ran

Publications
First:		Substrate pathways demonstrated by transplanted Mauthner axons. [J Comp Neurol 1981]
Most recent:		The Role of NEDD1 Phosphorylation by Aurora A in Chromosomal Microtubule Nucleation and Spindle Function. [Curr Biol 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		GTP binding GTPase activity small monomeric GTPase activity
Biological:		intracellular protein transport protein transport small GTPase mediated signal transduction
Cellular Component:
EC:		small monomeric GTPase
KOG:		[U] GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6581.1.S1_at [+] Str.6581.1.S2_at Str.44032.1.A1_at Str.44146.1.A1_at Str.47018.1.A1_x_at
Affymetrix 2.0			Xl2.51066.1.S1_at [+] Xl2.55052.1.A1_s_at

Symbol legend[+]