lmnb1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (37)

Nucleotides (539)

Interactants (45)

XB-GENEPAGE-489657

Gene Symbol: lmnb1 Gene Name: lamin B1 Synonyms: Lamin-L(I), lamin-b, lamin b, lamin b1 Add Xenopus synonyms Gene Function: nucleoskeletal protein Interactants: lbr(9) , lmna(7) , lmnb2(6) , emd(4) , hsp90aa1.1(3) , igf2bp3(3) , ran(3) View All

XB-GENE-489658

XB-GENE-489662

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_203867\|Xenopus (Silurana) tropicalis lamin B1 (lmnb1), mRNA CGATTGTATGCACATTTTACATTTTAATCCTTGCGGGGTTTTTCAATTTTAAAAAGTACTTGTATTTTAGACTGCGTGTGCTACTACGGGTGGAGTGCCCAGGAGGGGAAAGTTTGCAGGCAGTGCGGCGGTGAGTGTGTGTCGGCCGTCAAGTATAAAGGAGAGTTTAGCCTGAGAACCGGTACCGTCGCTCTTTTATATAACCATTAGAAGAAGCCAACTGTGCAATGGCCACCGCCACGCCAAGCGGCCCCAGGAGCTCCGGCCGTCGAAGCAGCATGAACACCCCGCTCAGCCCGACTCGTATCAGCCGCCTGCAGGAGAAAGTGGATCTGCAGGAGCTGAATGACCGCTTGGCCGTGTATATAGACAAGGTGCGCAGCCTGGAGAGCGAGAATAGCCTGCTCCATGTACAGGTCACCGAGCGGGAAGAGGTGCGGAGCCGGGAAGTGAGCGGCATCAAGGAGCTGTATGAGACCGAGCTGGCCGATGCCCGCAGGAGCCTGGATGACACTGCCCGGGAGAGAGCCCGCCTGCAGCTGGAGCTCAGTAAGATCTCCGTGGAACATGAGGATCTCCGTGCCAGTTTCTCAAAGAAAGAATCTGAATTGGAGTCGGCACAAGCTAGATTTAGAGAAACTGAAGCTCTTCTCAACTCAAAAAATGCTGCCCTTGCAACTACACAGAGTGAGAATAAGTCACTGCAAGGAGAGGTTGAGGACTTGAAAGCTGAAATTGGGCAGCTGGAATCCGCTTTGGCTCTTGCAAAGAAACAGCTTGAAGAAGAAATCTTGATAAAGGTGGATCTTGAAAACCGGTGTCAGTCCTTAATTGAGGAACTAGATTTCCGTAAAAACGTTTATGAAGAGGAAATAAAGGAGACTAGAAGAAGACACGAGACTCGCTTGGTGGAGGTTGATTCTGGCAAGCAAATAGAGTATGAACATAAACTATCACAAGCGCTTGCAGACATGAGGGAGCAACATGATTCTCAAGTTACACTGTACAAAGAAGAACTTGAACACACCTACCAATCTAAGCTGGAGAATGCACGACTATCCTCAGAAATGAACAGCTCTGCTGTAAATAGTACTCGAGAGGAGCTTATGGAAAGTCGATATCGAATTGACAGCCTCACATCCCAGCTTTCTGAGCTCCAAAAAGAGTCTAGAGCATGGCATGATCGGATGCAAGAACTAGAGGATATGCTGGCTAAGGAAAAGGACAACAGTCGCAAGATGCTTGCAGAGAGGGAGAGAGAAATGGCTGATATAAGAGATCAGATGCAGCAACAGCTTAATGACTATGAGCAGCTTCTAGATGTTAAATTGGCACTGGACATGGAAATAAGTGCATACAGGAAACTGCTGGAAGGTGAAGAGGAAAGGCTGAAGTTATCTCCGAGCCCCCCTTCCCGCGTGACTGTTTCTAGGGCTTCTTCAAGTCGCAGTGTGCGCACAGCTAAAGGCAAAAGAAAGAGAATTGATGTAGAAGAGTCTGAGGCCAGCAGCAGTGTTAGCATTTCTCATTCTGCATCCGCCACTGGGGATGTGAGCATCGAAGAAGTTGATGTGGATGGCAAATATATCAGACTGAAAAACAATTCAGAGCAGGATCATCCTTTAGGAGGTTGGGAACTGACCAGAACAATTGGAGAAGCATCTGTGAATTTCAAGTTTACCTCAAGATACGTACTTAAAGCAGGACAGACTGTCACAATCTGGGCTGCTGATGCAGGAGTTACAGCGAGTCCACCCTCTGACCTAATCTGGAAGAACCAGAACTCATGGGCAACAGGAGAAGATGTGAAGGTCATACTGAAGAATTCTCAGGGAGAGGACGTAGCACAGCGCACAACAGTATATACTACCACCATACCTGAAGAGGAGCTGGAAGAAGAAGAAGAAATGTTGGAGGAGATCACTAAAGAATCTCACTACTCTCAGCAGAAGTCAGGAAATAGAAACTGCGCCATCATGTAATACCAGTGTTCCACATTGTCCTACAGATCTGAGCCTTCTGGAAGCACAGCCTATTTTTGTATCATGTACAATTTACAGTGTCAGCATTGACTGCCTTAATATCTTTTCTACCAATGTAATGCAGGGGCATTTTGTACTAGAATCTGATTTTGCAAAAATGTGAATTGACTGTATTTTGTACACTGTCCTGGACGGTGGGTCCTGGAGTAGATATTTTTTGTTACTTGTGGCAGGAACATATCTACTGCCTATTGCTTATCCACTTGTCACACTTCCAAGGCACTGTGTGCAAAGGTGCTTGCAGGATCTCAGTCTCCCTCACTTCCATCTTTTGTACTGAGTTTTATTTTCTAGCACAAAATCAAGAATTTTAATTTTTTTTTTTTTTTTTTTGAAGCTTTGTTTTAATTTTTTATTGTGGAAAAAAATACAACATGTTTTATCATGACATTTTAGGTAACTGGTGGGGAAAGTAGCTTTTTTTATGGGGGGGGGGGGGGTAGCAAAACTTTTGTTTGTTTACATAAACAGAACAAAATAAAAGGGGGTTTAAAGAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001086584\|Xenopus laevis lamin B1 (lmnb1), mRNA GGGGGAGGGTGCTGAGCGAGTGCATGTGCGCGGGATTCGGCGCAATTTTAGCCCTTGGTTTTTAACGCACCTATTTTAATTATTGCTTTGGTTTTATTGTAAAAACACTGGTATTTCAAGCAGCGGGGGTGCCCAGGAGTGAGAGTTCGCGGGAGAATTTAGCCAGAGAACCGGTACCGTGAGAATCCGTCGTGCAATGGCCACCGCCACACCAAGCGGCCCCAGGAGCTCCGGCCGAAGAAGCAGCATGAGCACCCCGCTCAGTCCGACCCGGATCTCCCGGCTGCAGGAGAAAAGCGACCTGCAGGAGCTCAATGACCGCCTGGCCGTGTATATCGACAAGGTGCGGAGCCTGGAGAGCGAGAATAGTCTGCTGCATGTGCAGGTCACCGAGCGGGAGGAAGTGCGGAGCCGGGAAGTGAGCGGCATCAAGGAGCTGTACGAGACCGAGCTGGCCGATACCCGCAGGAGCCTGGACGACACTGCCCGGGAGAGGGCCAAGCTGCAGCTGGAGCTCAGTAAAATCTCCGTGGAGCACCAGGATCTCCAGGCCAGTTTCTCCAAGAAAGAATCTGAATTGCAATCGGCGCAAGCTAGATTTAGAGAAACTGAAGCTCTTCTCAACTCAAAAAATGCTGCCCTTGCAAATGCACAGAGTGAAAATAAGTCACTGCAGAGAGAGGTGGAGGAATTGAACGGTGAAAATGGGCAGCTTGAATCCGCTTTGGCTCTTGCAAAGAAACAGCTCGAAGAAGAAATCTTGATAAAGGTGGATCTTGAAAACCGGTGTCAGTCTCTAATTGAGGAACTAGATTTCCGTAAAAACATTTATGAAGAGGAAATAAAGGAGACTAGAAGCAGACATGAGACTCGCTTGGTGGAAGTTGATTCTGGTCGGCAAGTAGAGTATGAACATAAACTATTTCAAGCACTTACTGAGATGCGGGATCAACATGATTCTCAAATCACACTGTACAAAGAAGAACTTGAGCAGACTTACCAATCTAAGCTGGAGAATGCAAGACTAGCCTCAGAAATGAACAGCTCTGCTGTGAGCAGTACCCGAGAGGAGCTTACGGAAAGTCGTCTCAGAATCAACAGCCTCACTTCCCAGCTCTCTGAGCTCCAAAAAGAGTCTAGAGCATGGCATGATCGGATGCAAGAACTGGAGGATATGCTGGCTAAGGAAAAGGACAACAGTCGTAAAATGCTTGCAGAGAGGGAGCGAGAAATGGCAGATATAAGAGATCAAATGCAGCAACAACTTAATGATTATGAGCAGCTTCTAGATGTTAAATTGGCATTGGACATGGAAATAAGTGCATACAGGAAACTTCTGGAAGGTGAAGAGGAGAGGCTGAAGTTATCTCCCAGCCCTTCCTCACGGGTGACTGTCTCAAGGGCTTCTTCAAGTCGCGCTGTTCGTACAACTAAAGGCAAAAGAAAGAGAATTGATGTGGAAGAGTCGGAGGCCAGCAGTAGTGTCAGCATTGCTCATTCTGCCTCTGCCACTGGGGATGTGAGCATTGAAGAAGTTGATATGGAAGGCAAATATATCCGACTGAAAAACAATTCTGAGAAGGATCAGCCTTTGGGGGGTTGGGAACTCACCAGAACAATTGGAGAAGCGTCTGTGAATTTCAAGTTTACCTCAAGATACGTACTTAAAGCAGGACAGACTGTCACAATCTGGGCTGCTGATGCTGGAGTTACAGCAAGTCCACCATCTGACCTAATCTGGAAGAACCAGAATTCATGGGGAACAGGAGAAGATGTGAAGGCCACACTGAAGAATTCTCAGGGAGAGGAAGTAGCACAGCGCACAACCGTGTACACCACCAATATACCTGAAGAGGAGTTGGAGGAGGAAGAAGAAATATTTGAGGAGACTGCTAAAGAATCTCTCTACTCTCAGCAGAAGTCTGGAAATAAAAACTGCGCCATCATGTAATACCAGTGTTCTACATCATGACCTACAGATCTGAGCCTTCTGGAAGCACAGCCTATTTTTGTACCATTTACAATGTCAGCATTGACGGCCTTAATCTCTTTTCTACCAATATAACGCAGGGGCATTTTGTACTGAATCTGATTTTGCAAAATGTGAATTGACCGTATTTTCTACACTGTGTCCGGGCGGCAGGTCCTGGAGTGAAATATCTCTGCGATTGCTTCTCCACTTGTCTCACTTCAGACACCTTACCCCGAGGTGCTTCACCTTCTCCATTTCCCTCGCTTCCATCTTTTGTACCGAGTTTTCTTTTCTAGCACACAATCAAGAATTTTAATTTTGAAGCTGTTTTAAGGTTGTTTTTTAATCTTGTGGGGGAAAAACACAACTGTTTTATCAGGACATTTTAGATAACTGTGTGGCGGGTGGGTAAGTAGTTTGTTTTTTTTATTATTGGGGGGGATGAAAAGCTATTGTTTACTTAAAACAAAATAAAAGGGGATTTAAATACAAAAAAAAAAAAAAA
Protein		Refseq >NP_989198\|lamin B1 [Xenopus (Silurana) tropicalis] MATATPSGPRSSGRRSSMNTPLSPTRISRLQEKVDLQELNDRLAVYIDKVRSLESENSLLHVQVTEREEVRSREVSGIKELYETELADARRSLDDTARERARLQLELSKISVEHEDLRASFSKKESELESAQARFRETEALLNSKNAALATTQSENKSLQGEVEDLKAEIGQLESALALAKKQLEEEILIKVDLENRCQSLIEELDFRKNVYEEEIKETRRRHETRLVEVDSGKQIEYEHKLSQALADMREQHDSQVTLYKEELEHTYQSKLENARLSSEMNSSAVNSTREELMESRYRIDSLTSQLSELQKESRAWHDRMQELEDMLAKEKDNSRKMLAEREREMADIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPPSRVTVSRASSSRSVRTAKGKRKRIDVEESEASSSVSISHSASATGDVSIEEVDVDGKYIRLKNNSEQDHPLGGWELTRTIGEASVNFKFTSRYVLKAGQTVTIWAADAGVTASPPSDLIWKNQNSWATGEDVKVILKNSQGEDVAQRTTVYTTTIPEEELEEEEEMLEEITKESHYSQQKSGNRNCAIM	Refseq >NP_001080053\|lamin B1 [Xenopus laevis] MATATPSGPRSSGRRSSMSTPLSPTRISRLQEKSDLQELNDRLAVYIDKVRSLESENSLLHVQVTEREEVRSREVSGIKELYETELADTRRSLDDTARERAKLQLELSKISVEHQDLQASFSKKESELQSAQARFRETEALLNSKNAALANAQSENKSLQREVEELNGENGQLESALALAKKQLEEEILIKVDLENRCQSLIEELDFRKNIYEEEIKETRSRHETRLVEVDSGRQVEYEHKLFQALTEMRDQHDSQITLYKEELEQTYQSKLENARLASEMNSSAVSSTREELTESRLRINSLTSQLSELQKESRAWHDRMQELEDMLAKEKDNSRKMLAEREREMADIRDQMQQQLNDYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRAVRTTKGKRKRIDVEESEASSSVSIAHSASATGDVSIEEVDMEGKYIRLKNNSEKDQPLGGWELTRTIGEASVNFKFTSRYVLKAGQTVTIWAADAGVTASPPSDLIWKNQNSWGTGEDVKATLKNSQGEEVAQRTTVYTTNIPEEELEEEEEIFEETAKESLYSQQKSGNKNCAIM

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.44838 [+] Str.46907 Str.80328	Xl.295
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	LMNB1	OMIM:169500
mouse		MGI	Lmnb1	All(6) Gene Trapped(1) Targeted, other(2) Targeted, knock Out(1)
zebrafish		ZFIN	lmnb1

Publications
First:		Detection of nuclear lamin B epitopes in oocyte nuclei from mice, sea urchins, and clams using a human autoimmune serum. [Dev Biol 1987]
Most recent:		Autosomal recessive Emery-Dreifuss muscular dystrophy caused by a novel mutation (R225Q) in the lamin A/C gene identified by exome sequencing. [Muscle Nerve 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		structural molecule activity
Biological:
Cellular Component:
EC:
KOG:		[DY] Nuclear envelope protein lamin, intermediate filament superfamily

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.5943.1.S1_at [+] Str.44838.1.A1_at Str.46907.1.A1_at	Xl.295.1.S1_at
Affymetrix 2.0			Xl2.295.1.S1_at

Symbol legend[+]