dbf4b Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-5829757

[provisional- machine annotated only]

Gene Symbol: dbf4b [Predicted: Source is Human Entrez Gene]

Gene Name: DBF4 homolog B (S. cerevisiae) [Predicted: Source is Human Entrez Gene]

Synonyms: dbf4 Add Xenopus synonyms

Gene Function: Protein kinase essential for the initiation of DNA replication

Interactants: dbf4(14) , cdc7(13) , diaph1(5) , antxr1(4) , atr(4) , cdc45(3) , cdc6(3) View All

XB-GENE-5829758

XB-GENE-5829790

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	NCBI Nucleotide >XM_002935560\|PREDICTED: Xenopus (Silurana) tropicalis DBF4 homolog B (S. cerevisiae), transcript variant 1 (dbf4b), mRNA ACGGGGCCTAAGGGTAGAGTTGTGGTGCTGTCAGCACAGGCAGGCTGCATCTATCGTTATCTTGTATGTGACTTGTGTCAATGGCCGATCGGAGCCCTGTTCTTCATGGTCAGGTGATGCAGCAGGATGAAGAGCCTCCTTTGGCCAAAAAACGTCGATGCAGGGATATCGTCTTTGCGGGGAAGTCGTTCTACCTTGATCTACCAGCCAACAGACAGACGCAGCTTCTAACTAAAGCCATTGGCAGACTTGGAGGGGTCATTGAGGGCTTCCTGAGTAGAGATGTAAACTATATGGTGACTGGCAGCAAGAAGGCAGTGACCAGTGTGAGCTCTGCGGCTACTAGAAGAGGGGAAAAGTCTCAGAGCCAGGCTGCAGAACGGAAGGAGCTTATTCATTGTAGCCGTGGGAAGCAGCTTCTGAAGAAAGTCATTCAGAGCCAGGAGTGCAACAGTGTCCTCACCAGCGCCTGTTCTTGGGGGGTCTCGGTTCTCTATGTGGAAGAGGTTTTGGCTTACATAGAGAGTCTGGAGCGTCCTCCCTCACGTGAGATCCAGAATAAAACTGCTGAAGTCAGGGCTTTAGATTCTACAAGGCCAAGTCTGAAAATTGCAAGACTGAGGAGCCCATTCATAAAGATTGAGGATCAGAGCAGAAAGTTTCGCCCTCTGCAGTGCACCTTCACCAGCTTTCCGGAGCTCTCATTCACGTGTTCAGATAAGAGCCCCTTTGAGACAGCCCAGACAGTCAACAGGTCCCATAAAGAGAAGGACCATGGTGATCAGGAGGAGGATGAAGGACAAAGAAGTCAGAAGCCCCAAGCAAAGAAAAGGAAAGGCTATTGCGAGTGCTGTGAGGAAACATTTGACTCCCTGAGTGAGCATCTGGTTGGTGAGCACCACTCGCGTTTTGTTTCCAAACCTTTAAGTTACAAGATGATTGATGAGCTTGCAGCCCAGCTTACCTGTGACCTGATGGAAAAGCCTTTCGGGTCACCCCTAAGCCCAGAAGCTGAGAGGTCTACACAAAAGGAAGGCTGGAATTTGGGTCTGGCACCTGGTGATGCAGAGCCTGCAGGGAATAAGGCAGAGGAGCTGGATATCCATAAGGCTGCATGTTTGGACAAGGATGGGCGTGCTGGGTGTGAAGATATCATAGATGCACCTGCACAGCTAAGTGATGGTGTGGCGCAAAGGCCAGATCAGGGATGTGGTGAAATTCCATTAGCCAAAGTAGCAGTGGAGCTTTACAATGTGTGCTGTTCTGATCAAACTATTGTCACTTGCCCCATTGAGCTGCCAGATGTAAGTGCCAAAGACAAGCTATGTGGTAACTTGTTAGGCAATGCCGTGGGTGATGAGCAGGTGCTGCAGGGGACTAAAAACACATCTGAATCTCATATGGATCTTGGGAATGGAATAGGGCTGGTGCATGCAGAACTGCATAAGCATCCACTAACAAAGGATTCTCAAACAGAGCCGCTCTCTCATGCACTGGGTGAGTCACACAAACAGCTTCCAACAACAGATGTTGCCGATGGTCAGTGTATACTACTAGGGGGAGCATCAGTTATGCAGCTTCCATTTCATGGTGGCACTGGCGGGTCACAGAGCCATGTGACAACCTGTGAAGATGCTAATAAGCCACGTACTGAGCATCGTCTGTATGATTCCCCAGTTGGGTCTCGTGCAGAACCAAATGTGAGTGATGCTATTGCCATGTCTTGTGTAATACCTGCTCTAGATAATGCACTTGGAGGAACTTGTGTGGATGCCACTATGCAGTCACATTGGGAGCTGCCATTGGGAGGTACCACTGATACCCAAAACACTCTGCTCAGTTACAGCACTACAGTGACTGTTGGGGAGCTGGGCCTTAAATCTCAGCACCCCACTCCAGAACAACCACCACTGCTCATTTCTACTTGTTCATCCATTACCACTGTTTGCTGCACAGATACAGAGTTTAAGACTTGCACCGTGCGTGTTCATTCCACCTCTCACTCACCGCCCAGTCAGACACTGAAAAGTAACCAAACACCATCTTTGGTGGAAAAGGACCTTACCAACACGAACTGCCACCGAGCCAAACGGAAACATTGTGAGTCACTGCTATCCCCACCTGCAAAAAGGCACATAAGCATAGATGGCCCGTCCCACTGCCAACCTTTGACTTTGCCTATGTGGCTTTTATGCCAATTTCCTAATTATGGGCAGCAGGTACAGGTGCCAGTCTGGGCAGACTTGGGCAAGTGGGATAGCACTGTGGTGAAGGAAGAGGGAACGGTTGATTGCAGTTCCTCTTCTACTCTTCCTAAAGTGCACCAGGACAGTTTCTCTTCTGAGTCAGACTGGGATGCCCACCTGCCAGCTTTTTTCCAGAATAACCCACAGCAGACCTTGCAATGTGGGGACCTGAGGATGGCTCAAGTTACCCTGAATGAGAGCTGGTATGGAAAAGAGTTGTGCAACATACTGACCCATGATCCATAACCTGGACCACTATCCCCTAGTTCCTGGCAACTGGCATTGCTGGAAAGGTTGAAGGAGAAGGTAAAACTGACTGTGTGCACTGCAAAAACCCACTTTGGGAAACTTACCCTTTTTGAGTGTTTTTTTTTTTTTAGCATGGTTTTTCATTTTTCTGTCCCTTTATGTCGGTGTTTATCTTTTGGAAGCGCCTTACTCTCCTGCTTTGTGTGTATGTGCCTCCCCACCCCCGTCCTTCCGGAATGGCTGTGTCAGACGAGAGCCCTCAGCCCCTGCCCAGAGCTCTTAACTGCTTCTTAATGACTCCTAATGGGTTGAAGAAGTTTTAGATGGAATTGAAATGCCTCCTCTAATCGTG	Refseq >NM_001089271\|Xenopus laevis DBF4 homolog B (S. cerevisiae) (dbf4b), mRNA ATGGCCAGTGTGATCTCTGTTCTGCATGGTCAGGTGATGCAGCAGGACGATGAACCCCCATTGGCCAAGAGACGTCGCTGCAGGGAGATTACCTTTGCGGGGAAGTCGTTCTACCTGGATGTGCCGGCCAACAGACAGACGCAGCTCCTGACTAAAGCCATCGGAAGACTTGGAGGGATCATCGAGAGCTTCCTGAGCAGAGATGTCGACTATGTGGTGACTGGCAGCAAGAAAGCAGTGGCCAGTGTGAGCTCTGTGGCTACTAGAAGAGGAGAAAAGTCCCAAATCCAGGCTGCGGAACGGAAGGAGCCCATTCACTGTAGCCGTGGGAAGCAGCTTCTGAAGAAAGTCGTCCATAGTCAGGAGTGCAACAGCGTCCTCACCAACGCACGTTCTTGGGGAGTCACGGTTCTCTACGTGGAAGATGTTGTAAGTTATATAGAGCGTCTGGAGCGACCTCCCTCTCGTGGAATCCAGAATAAAACGGCAGAGGGCCGAGCTGCAGATTCTACAAGGCCAAGTCTGAAAATCGCGAGACTGAGGAGCCCGTTCATAAAAATTGAGGATCAGAGCAGAAAGTTTCGCCCTCTACAATGCACTTTTACAAGCTTCCCAGAACTCTCGTTTGTGTGTTCCGATAAGAGCCCCTTTGAGACTGTCCAGACAGTCAAAAAGAAGGATCCTGGTGATCAGGAGGAGGAGGAAGGACAAAGAAGTCAGAAGCCCCAAGCAAGGAAAAGAAAAGGTTATTGCGAATGCTGCGAGGAAACCTTTGACACCCTGAGTGAGCATCTAGTTGGTGAGCACCACTTCCGATTCGTTTCCAATCCTTTGAGTTACAAGATGATCGATGACCTTGCTGCCCAACTTACCTGTGACCTCATGGAACTGCCTTTTGGGTCACCCACAAGCCCAGAAGCTGAAAGATCTTCCCAAAATGAGGACTGGGATTTGGATCTGGCACCTGGTGAGGCAGAGCCTGCAGGGAATGAGGGACATGAGCTGGGAATCCTTAAGGCTACAAGGTTGGACAAGGATGGACATGCTGATTGTGAAGATCAAGGTGCTCCTGCGTATTTAAGGGACGGTGGGGCAGAAGAACCAGATCAGAGATGTGGTGAAATCCCATTGGCCAACATAGAAGTTGATGTTTACAATGTCTGTTCTTTTGATCAACCTGTTGTCACGTGTACCATGGAGCTGCCAGATGTAAGTGCAGAAGGCAAGATCCATAGTAACTTGTTAGGCAGTACTGTGGGTGATGAGCGGGTGCTGCAGAGGACTAATGGCACGTGTGAGCCCCACATAGACCTGGCTCTTGGGAATGGAAGAGAACTGAAACATGCAGAGCTACAGAAGGATCCATTAACAAAAGATTCACAACCAGAGCTACTTTCTACTGCACATGAACAACTTCCTACCAGTGCTCCGTGTATGCTACTAGAGGGAGCATCTGTTGTGCATTTTCCATCTCACGGTGGTACCGTCGGGTCACAGGGTGATGTGACCTCCCATTCAGCTGCTAATAAGCCACACACTGAGAACTGTCCGGTAGATTCCACAGGTGACCGTCACGCACAACCAGCTGGGAGTGATGCCCTTGCCATGTCTTGTGTAATTCCCACTCTGGATAATGGAGGAAGACACGTGGATGCCACAATGCAGTCACACTGGGAGGTGCCGTTGGGATGTACCACTGACACTCTGCTCAGTTACAGCACTACAGTGACTGTTGGGGAGCTGGGCCCAGAAGCTCACAATCCGACTCCAGAACAACAGCCACTGCTCATATCTACTTGTTCATCCATTACCACTGTTTGCTGCACGGATACAGAGTTTAAGAGTTGCACCGTGAGTGTTCATTCCACGTCCCACTCTCCACCCAATCAGAATGTGAAAAGTAACCAAACCCCATCTTTGCTTGAAATGGACCTTGCCAACCCGAACTGCCACAGAGCCAAACGGAAACACTGGGATTCACTTCTATCCCCTCCAGGGAAAAAACCCACTAGCCCTTCCCACTGCCAATCTTTGACATTGCCCATGTGGCTTTTATGCCAGTTTCCTAATTATGGGCAGCAGGTACAGTTGCCTGTGTGGGCAGATTTGTGCAAATGGGATGGCACAGCGGCAGCGGAAGAGGGGACGGTTGATTGCAGTTCTTCTTCTACTCTTCCTAAACTGCACCAGGACAGTTTCTCTTCTGAGTCCGACTGGGATGCCCACCTGCCATCTTTTTTCCAGAATAACCCACAGCAGAGCTTGCAGTGTGGGGATCTGAGGACAGCCCAGGTTACCCTTAATGAGAGCTGGTATGGGAAACAGCTGTGCAACATTCTGACCCATGATCCATAACCTCTGCAGCGTTATCCAGTTGTAACTGTTGGGAAAGTTGATGGAGAAGGTACGATTGACCATGTGAACTGCAAAAACCCATAATGCTAAATGTCCCCTTTTGTTTTTTTAGTATCCATTTTGTTCTTCGTTTTTCTGTCCCTTTATAGGGTTATTTTGTGAGTGTTTATCTTGCACAAGTGCCTTCTCTTTTCTGTTTTGTGGATCTCCCCACCCCCTTCCTTCCCGGAACGGGTAAGTCAGATGGAGACCTCTGCCTCTGCCCAGAGCTCTTAACTGCTTCTTAATGACTTAATGGGTTGAAGAAGTTTTTTAGATGGAATTAAAATGCCTCCTCCAATCGTGCCAGACTCACCAAGCTATGAACTCATCCTGTCTACAAACTGATCCATTGCCTTCAGCAAAGGAACATTAATGGCTCTCTCACTGGGAGCAAAATGGGCCCTAAAGTTGCATGTGAATATGTTTAAACAGGCAGGTCCTGTTTTTTCAGCCTAATTCATGCATGTGTGTCTTGAGACCCCTTTGCTGGGATTTGTAGTTCTGCCCCAGCTGAGACGGGTGCAACAGGGTAGACATTCCTGACCTACGGTGCCCCCTTGGGCCAAAGGTCACCCATTTATAAATAGCAGCACATGGGACTTTTTTGGGGGCCTGTCATGCTAGCATATTGTTGTCATGTGAGCTTATTTTAGTTGAAAACAACAATAGTTAAAGGACAAGGAAAGGCTTAATCACTGGGAGCTGTTTGGCACCCCAAGGTAATAATATAAGGATTGCAGTGCCGCCATTGTGTTTCCTGCTCCAGGATTCTTGCTACTGCCCTGGGCTGTACTCGTGCAATAGAGCAAATAGCTCTCTTACACCAGCTACAAGGTGCTGGTGTGTCACCCAGGGTCATAACTGAGCACCCCCAAGTGATGAAGCCTTTCCTTCTCTTTTAATAGCCAACTCAACACTAGAAGTCAATTGCTTTTGTACTCCGAATTATCTGGTTGGACATACCATCGGTAGCTTAAGTTACTGATGCACTAAGCATCTCCTTCCCTTTCTCTGCTCGTTTCCATGGACCAGTGAGAGGCTTGTATTTATACATCACATTTTTAGACAACTACGTTTTATTGGAAACTCATTTTGGCCATACAGTAATAAAATCGGCATTACCAGGATAGCCGAACCCATCTGAAACTGCAGTTGTTGATTGACTGTGGCTGCTGGGAGTTCATCTAATACGTATGTATCCCTAAGAAAGGAACAGCCCAGTAGTAGGCACCATCTATACCTCTACACATTGTAACTTCTCAGTGCATTTATTACCAACCATGCTATGTATTTTATTGAAACGTTTGTTTGCTATGAATAAAATTTGTTTTTTTTTTTYTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAA
Protein	NCBI Protein >XP_002935606\|PREDICTED: protein DBF4 homolog B isoform 1 [Xenopus (Silurana) tropicalis] MADRSPVLHGQVMQQDEEPPLAKKRRCRDIVFAGKSFYLDLPANRQTQLLTKAIGRLGGVIEGFLSRDVNYMVTGSKKAVTSVSSAATRRGEKSQSQAAERKELIHCSRGKQLLKKVIQSQECNSVLTSACSWGVSVLYVEEVLAYIESLERPPSREIQNKTAEVRALDSTRPSLKIARLRSPFIKIEDQSRKFRPLQCTFTSFPELSFTCSDKSPFETAQTVNRSHKEKDHGDQEEDEGQRSQKPQAKKRKGYCECCEETFDSLSEHLVGEHHSRFVSKPLSYKMIDELAAQLTCDLMEKPFGSPLSPEAERSTQKEGWNLGLAPGDAEPAGNKAEELDIHKAACLDKDGRAGCEDIIDAPAQLSDGVAQRPDQGCGEIPLAKVAVELYNVCCSDQTIVTCPIELPDVSAKDKLCGNLLGNAVGDEQVLQGTKNTSESHMDLGNGIGLVHAELHKHPLTKDSQTEPLSHALGESHKQLPTTDVADGQCILLGGASVMQLPFHGGTGGSQSHVTTCEDANKPRTEHRLYDSPVGSRAEPNVSDAIAMSCVIPALDNALGGTCVDATMQSHWELPLGGTTDTQNTLLSYSTTVTVGELGLKSQHPTPEQPPLLISTCSSITTVCCTDTEFKTCTVRVHSTSHSPPSQTLKSNQTPSLVEKDLTNTNCHRAKRKHCESLLSPPAKRHISIDGPSHCQPLTLPMWLLCQFPNYGQQVQVPVWADLGKWDSTVVKEEGTVDCSSSSTLPKVHQDSFSSESDWDAHLPAFFQNNPQQTLQCGDLRMAQVTLNESWYGKELCNILTHDP	Refseq >NP_001082740\|protein DBF4 homolog B [Xenopus laevis] MASVISVLHGQVMQQDDEPPLAKRRRCREITFAGKSFYLDVPANRQTQLLTKAIGRLGGIIESFLSRDVDYVVTGSKKAVASVSSVATRRGEKSQIQAAERKEPIHCSRGKQLLKKVVHSQECNSVLTNARSWGVTVLYVEDVVSYIERLERPPSRGIQNKTAEGRAADSTRPSLKIARLRSPFIKIEDQSRKFRPLQCTFTSFPELSFVCSDKSPFETVQTVKKKDPGDQEEEEGQRSQKPQARKRKGYCECCEETFDTLSEHLVGEHHFRFVSNPLSYKMIDDLAAQLTCDLMELPFGSPTSPEAERSSQNEDWDLDLAPGEAEPAGNEGHELGILKATRLDKDGHADCEDQGAPAYLRDGGAEEPDQRCGEIPLANIEVDVYNVCSFDQPVVTCTMELPDVSAEGKIHSNLLGSTVGDERVLQRTNGTCEPHIDLALGNGRELKHAELQKDPLTKDSQPELLSTAHEQLPTSAPCMLLEGASVVHFPSHGGTVGSQGDVTSHSAANKPHTENCPVDSTGDRHAQPAGSDALAMSCVIPTLDNGGRHVDATMQSHWEVPLGCTTDTLLSYSTTVTVGELGPEAHNPTPEQQPLLISTCSSITTVCCTDTEFKSCTVSVHSTSHSPPNQNVKSNQTPSLLEMDLANPNCHRAKRKHWDSLLSPPGKKPTSPSHCQSLTLPMWLLCQFPNYGQQVQLPVWADLCKWDGTAAAEEGTVDCSSSSTLPKLHQDSFSSESDWDAHLPSFFQNNPQQSLQCGDLRTAQVTLNESWYGKQLCNILTHDP UniProtKB

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.57906	Xl.44935
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	2 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	DBF4B
mouse
zebrafish

Publications
First:		Protein kinase A is required for chromosomal DNA replication. [Curr Biol 1999]
Most recent:		Drf1-dependent kinase interacts with Claspin through a conserved protein motif. [J Biol Chem 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		nucleic acid binding sugar binding zinc ion binding
Biological:
Cellular Component:
EC:
KOG:		[LD] Protein kinase essential for the initiation of DNA replication

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.51507.1.S1_at [+] Str.51746.1.A1_x_at Str.51746.1.A1_at Str.20326.1.S1_at
Affymetrix 2.0		Xl2.44935.1.S2_at

Symbol legend[+]