Gene post encodes an endoplasmic reticulum membrane protein with pomst1 and pomst2 domains. the protein localizes to the endoplasmic reticulum. it is involved in protein o-mannosylation, a key step for...[+]

Gene post encodes an endoplasmic reticulum membrane protein with pomst1 and pomst2 domains. the protein localizes to the endoplasmic reticulum. it is involved in protein o-mannosylation, a key step for dystroglycan modification, which is necessary for muscle integrity. expression is detected in the developing brain, eye, neural tube, somites, and pronephros during embryogenesis. [-]

MalaCards, KEGG Disease, DECIPHER, COSMIC, dbVAR, GHR, gnomAD