cap1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (9)

Nucleotides (375)

Interactants (18)

XB-GENEPAGE-5929501

Gene Symbol: cap1 Gene Name: CAP, adenylate cyclase-associated protein 1 Synonyms: xcap1 Add Xenopus synonyms Gene Function: Adenylate cyclase-associated protein (CAP/Srv2p) Interactants: cap2(2) , prss1(2) , bmp4(1) , cftr(1) , ctsl1(1) , fubp1(1) , hap1(1) View All

XB-GENE-5929502

XB-GENE-5929770

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001001239\|Xenopus (Silurana) tropicalis CAP, adenylate cyclase-associated protein 1 (cap1), mRNA GGAACCGGTACCTTATGTAGAGTAGACAGCAAGGTGTTGTGGGCACATTGTGTGTGTAAAACCTGTATGTCATGGCAGATATTCACGGCCTAGTTGATCGTCTGGAGAAGGCTGTTGCAAAATTGGAGATTCTTGCTGCAGGTTCTGGTGGGGATGTATCTTCTGCAGATACAGCTGTATATGTTCAGGCATATGATGATATCATTAATGGACAAGTGGCGGAATTCATGAAGAAAAGCAAAGAGATTGGTGGGGATGTTGAGAAGCAGGCTGACATGTTTATGTCAGGCATACAATTGCAGAGAGCAATTTTGGTGATGGCCTCTCAGTATCAGCAGCCAGCAGAGAAAGATCTCTCTGCTATCCTTGCCCCCCTCTCTGGAAAAATTCAAGCTGTGCAGGATTTTCGAGAAAAGAATCGAGGAAGTAAATTGTTCAACCATTTGTCTGCATTAAGTGAAAGTGTCCCTGCCTTAGGGTGGGTGGCAGTGGCACCTAAACCAGGTCCCTATGTGAAAGAAATGATGGATGCTGCCACGTTTTACACCAATAGAGTACTGAAGGAATATAAAGATGTGGATAAGAAACATGCTGACTGGGTGCGAGCATATTTAAATATCTGGAATGACCTGCAGACTTACATTAAAGAACATCACACAACTGGTCTAAATTGGAAAAAGACGGGTCCCAAGGCTTCAGGTGTCGCTCCTACTCCTGCTGCTCCTCCAGCACCCAAAGCAGGTCCCCCACCTCCTCCACCTGGTGGTCCTCCACCTCCTCCTCCCCCTGCACCAGCCTCTGCTCCAGATGATGACAGTGTGAGCCGCTCCCAGCTTTTTGCACAGCTTAATCAAGGAGAGAAAATCACCAAAGGTTTGAAACATGTTTCTGACGACATGAAGACCCATAAAAATCCTTCTCTGAAGACTCAAGGAGGTCCAGTCCGCGCCGGTCCCAAACCCTTTACTTCACCTAAACCCACAGGTTTTGGTGCCCCAGCAGCAAAGCCTGTTGTCAAGAAGCAGCCTCCTGTGCTGGAGCTGGAGGGCAAGAAATGGAAAGTGGAGAACCAGGAAAATGTGTCTAATCTAGAGATCGCTGACACTGAACTCAAGCAGGTTGTTTATATCTTCAAGTGTGTCAACAGCACCTTGCAAGTTAAAGGAAAGATCAATTCCATTATTGTGGACAACTGCAAGAAACTTGGGCTGGTTTTTGAAGATGCTGTTGGCATAGTAGAGATCATTAACTCAAAAGATGTTAAAGTGCAGGTGATGGGGAAAGTGCCAACAATATCTATCAATAAGACTGATGGCTGCCATGTGTACTTAAGCCAAGGCAGCTTGCAGTGTGAGATCATCAGCGCCAAATCCTCAGAGATGAATATTTTGGTTCCTACCAGTGGAGGAGAATTTAGTGAATTTCCAGTGCCAGAGCAGTTTAAAACTGTGTGGAATGGCCAGAAGTTGGAGACCACAGTTACAGAAATTGCAGGATAAATACGGTTATTTGTCTGCGGGAACAGACCACGGCCTGGACACTGTGTCCTCTATATTTTCCTGTGTTCTCTCTGCTGCTTATCTCGGGGATTATCCTAGCTGTAGCTTAGAAGCCTCTTGCTCACAGCTATCTTCTGCATAGCATCCTGCTATATGACACCTAACTAGTGCCAGAATCCCCTTGAAGAGCGCCCTTGCTATTCACAGCTATACCTATTCCCTTATGCCCATTCCAGTCCATGGGGCTGCAAAATATTTGCTGTTCAAATAGTGGTTGGATGACCAGTAGATGGTTAATTGGACCAAAGTAAAAAAGGGTACAGAGCACTTTGGTAATGGTTTTGTGTATGTTGTTCTCCGACTGCACAAAAGGACTATTGCAGCCCCTATATACTTAATATCTTGAATTATCTTTCCAGCACTTCTAGGGTTTTGTTTCCCCCTTAAGTCTTAAAAAAAAAAATTATGCAAACTTTCCTTATTTTTGACCTATAACTTTTACTGATCCAGAAACTAATGTTATGCCAATGTGTACTGAACATTTCGTGCTAAGTGGGCTTTGACCCCCCATTAAGGGAACAGGTGCAGCCCCTGCACAAACTATGGAATATACAATGAGTTTACAAATCAAGCATTTTATTAAAGAATCAATGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001089170\|Xenopus laevis CAP, adenylate cyclase-associated protein 1 (cap1), mRNA GCAGAGTAGACTGCAGGGTGTTGCGGGCAAATTGTGTGTGTAAAACCTGTGTGTCATGGCAGATATTCACGGCCTAGTTGATCGCCTGGAGAAGGCTGTTGCAAAATTGGAGACTCTTGCTGCAGGCTCTGGTGGAGATGCATCTTCTGCAGATACAGCTGTATATGTTCAGGCATATGATAATCTCATTAATGGGCCAGTGGCAGAATTCATGAAGAAGAGCAAAGAGATTGGTGGGGATGTTGAGAAGCAGGCTGATCTGTTTAGGTCAGGCATACAATTGCAGAGAGACATTTTGGTGATGGCCTCTCAGTATCAGCAGCCAGCAGAGAAAGATCTATCTGCTATCTTTGCCCCCCTCTCTGGAAAAATTCAAGCTGTGCAGGATTTTCGAGAGAAGAATCGAGGGAGTAAATTGTTCAATCATTTGTCTTCATTAAATGAAAGTGTCCCTGCCCTAGGTTGGGTGGCTGTGGCGCCTAAACCAGGTCCCTTTGTAAAAGAAATGGCGGATGCTGCCATGTTTTACACCAACAGAGTACTGAAGGAATATAAAGATGTGGATAAAAAACATGCTGACTGGGTCCGAGCATATTTAAATATTTGGACTGACATGCAGACTTATATTAAAGAACATCACACAACTGGTCTAACTTGGAAAAAGACGGGTCCCAAGGCTTCAAGTGCTGCTCCTGCTCCAGCTGCTCCACCAGCACCCAGGGCAGGCCCTCCACCTCCTCCACCTGGTGGTCCTCCACCTCCTCCTCCTCCTGCACCAGCCTCTGCTCCAGCTGATGACAGTGTGAGCCGTTCTCAGCTTTTTGCACAACTTAATCAAGGAGAGAATATCACCAAAGGTTTGAAGCATGTTTCTGACAACATGAAGACCCATAAGAATCCTTCTCTGAAGACTCATGGAGGTCCAGTCCGCTCTGGTCCCAAACCCTTTACTTCTCCCAAACCCACAAATGTCAGTGCTCCTGCAGCAAAGCCCGTTGTGGTGAAGAAGCAGCCTCCTGTACTGGAGCTGGAGGGCAAAAAATGGAAAGTGGAGAACCAGGAGAATGTGTCCAATCTGGAGATCACGGACACAGAACTCAAGCAGGTTGTATATATCTACAAGTGTGTGAACAGTACCTTGCAGGTGAAAGGAAAGATCAATTCCATTACTGTGGACAACTGCAAGAAACTTGGGCTGGTCTTTGAAGATGCTGTTGGCATAGTAGAGATCATTAACTCAAAAGATGTTAAAGTGCAGGTGATGGGTAAAGTGCCAACAATATCTATCAATAAGACTGATGGCTGCCACGTGTACTTAAGTCAAGACAGCTTGGCCTGTGAGATCATCAGCGCCAAATCCTCAGAGATGAATGTTCTGGTTCCTACCAGTGGAGGAGATTTTAATGAATTTCCAGTACCAGAGCAGTTTAAAAGTCTGTGGAATGGTCAGAAGTTGGTGACCACAGTGACAGAGATTGCAGGATAAACACGGTTATTTGTCTGCAGGAACAGACCACGGCCTGGACACTGTGTCCTCTTTATCTCCTGTGTTCTCTCTGCTGCTTATCTCGGGGATTATTCTAGCTGTAGGTTAGAAGCTTCTTGCTCACAGCTATCTTCTGCATAGCATTCTGCTATATAACATCTAACTAGTGCCAGAATCCCCTTGAAGAGCTGCGCTTGCTATTCATATCTATTCCCTTGTGCCCATGCCAGTCCATGGGGTTACAGAATATTTGTTCAAATTATTGTGGCTAGAGGTTGGATGACCAGTAAATGGTTAATTGGACCAAAGTAATAAAGGGTACAGAGCACTTTGGTAATGGCTTTGTGTATGTTGTTCTCAGACTGCACAAAAGAACTGTTGCAGCCCCCATATATTTAATATCTTGAATTTTCTTTCCAGCATTTCTAGGGTTTTCTGTTTTCCCCTTACGTCTTTAAAAAAAAAATATGCAAACTTCCTTTCTGACCTGTAACTTCTCTACTGATCCAGAAACTAATGTTATGCCAATGTGTACTGAACATTTCGTGCTAAGTGGGCTCTGACCCACATATTAAGGGAACCAGTGCAGCCCCTGCACAAATTATGGATTATACAATGAGTTTACAAATCAAGCATTTTATTAAAGAATCAATGTTAAAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001001239\|CAP, adenylate cyclase-associated protein 1 [Xenopus (Silurana) tropicalis] MADIHGLVDRLEKAVAKLEILAAGSGGDVSSADTAVYVQAYDDIINGQVAEFMKKSKEIGGDVEKQADMFMSGIQLQRAILVMASQYQQPAEKDLSAILAPLSGKIQAVQDFREKNRGSKLFNHLSALSESVPALGWVAVAPKPGPYVKEMMDAATFYTNRVLKEYKDVDKKHADWVRAYLNIWNDLQTYIKEHHTTGLNWKKTGPKASGVAPTPAAPPAPKAGPPPPPPGGPPPPPPPAPASAPDDDSVSRSQLFAQLNQGEKITKGLKHVSDDMKTHKNPSLKTQGGPVRAGPKPFTSPKPTGFGAPAAKPVVKKQPPVLELEGKKWKVENQENVSNLEIADTELKQVVYIFKCVNSTLQVKGKINSIIVDNCKKLGLVFEDAVGIVEIINSKDVKVQVMGKVPTISINKTDGCHVYLSQGSLQCEIISAKSSEMNILVPTSGGEFSEFPVPEQFKTVWNGQKLETTVTEIAG	Refseq >NP_001082639\|CAP, adenylate cyclase-associated protein 1 [Xenopus laevis] MADIHGLVDRLEKAVAKLETLAAGSGGDASSADTAVYVQAYDNLINGPVAEFMKKSKEIGGDVEKQADLFRSGIQLQRDILVMASQYQQPAEKDLSAIFAPLSGKIQAVQDFREKNRGSKLFNHLSSLNESVPALGWVAVAPKPGPFVKEMADAAMFYTNRVLKEYKDVDKKHADWVRAYLNIWTDMQTYIKEHHTTGLTWKKTGPKASSAAPAPAAPPAPRAGPPPPPPGGPPPPPPPAPASAPADDSVSRSQLFAQLNQGENITKGLKHVSDNMKTHKNPSLKTHGGPVRSGPKPFTSPKPTNVSAPAAKPVVVKKQPPVLELEGKKWKVENQENVSNLEITDTELKQVVYIYKCVNSTLQVKGKINSITVDNCKKLGLVFEDAVGIVEIINSKDVKVQVMGKVPTISINKTDGCHVYLSQDSLACEIISAKSSEMNVLVPTSGGDFNEFPVPEQFKSLWNGQKLVTTVTEIAG

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.43589 [+] Str.15337 Str.65094	Xl.83160
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		4 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human			CAP1
mouse		MGI	Cap1
zebrafish		ZFIN	cap1

Publications
First:		An epithelial serine protease activates the amiloride-sensitive sodium channel. [Nature 1997]
Most recent:		Mutations of the serine protease CAP1/Prss8 lead to reduced embryonic viability, skin defects, and decreased ENaC activity. [Am J Pathol 2012]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		histamine receptor activity
Biological:		G-protein coupled receptor protein signaling pathway
Cellular Component:		integral to membrane membrane
EC:
KOG:		[ZT] Adenylate cyclase-associated protein (CAP/Srv2p)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.2788.1.S1_at [+] Str.15337.1.A1_at Str.43589.1.A1_at	Xl.23428.1.A1_at
Affymetrix 2.0			Xl2.23428.1.S1_at

Symbol legend[+]