[provisional- machine annotated only] Gene Symbol: p2rx2 [Predicted: Source is Human Entrez Gene] Gene Name: purinergic receptor P2X, ligand-gated ion channel, 2 [Predicted: Source is Human Entrez Gene] Synonyms: p2x2, p2x(2) Add Xenopus synonyms Gene Function: Interactants: p2rx4(13) , p2rx7(5) , p2ry1(5) , pik3ca(2) , pik3cb(2) , pik3cg(2) , pycard(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1
mRNA		Jgi mRNA >Xetro.A01052.1 CTCTGGTCGTATGAAACACCCAAAGTAATTGTGGTAAAGAATCGTCGCCTGGGGACCATCTATAGGCTTTTACAACTTCTCATCGTTGTGTACTTTGTCTGGTATGTATTTGTGGTACAGAAAGGGTATCAGGCACAAGAGACAGGCCCGGAAAGTGCAGTCATTACAAAAGTAAAAGGGGTCTCTACCTCCAAAGGCCCCAGAGGAATAAAGAAGATCTGGGATGTAGCTGAGTATGTGAAGCCTCCAGAGGGGGGCAGCGTTTTCACTATTATAACCAGGATAGAGAGCACCAAGCTACAGACCATGGGAACTTGCCCAGAGAGTAGGACTGTACCTAATGCTTTGTGTGTCTCTGATGAGGACTGTAACCGCGGAGAGATGCATATACTGGGGAATGGGGAGCAGACAGGACGCTGTATCATCGCTGGACGTGGATCACTCAGAACATGTGAGATATATGCTTGGTGCCCCTTGGAAGATGAAACAGCGATCAGTGAATCCCTCCAGGATTACGTCCAGAACTTTACCATATTAATTAAGAACAACATCCATTTCCCTCAGTTTGGATTTTCCAAAGGAAACATAGAGGGCCAGGGATTCTTAAGGAACTGCACCTACCACCCAGTTCTATCTCCTTCCTGTCCCATATTCACTGTGGGTTTCATTGTGAGTGAGGCTGGAGCAAATTTCACAGAGCTGGCAAAGAAGGGAGGAATTATTGGAGTGATCATCAATTGGAATTGTAACCTGGATTTGCACCCTTCAAAATGCCGGCCTGAGTACTCATTCAGACGCCTTGATTTGCAGAACAAAATATCTTCTGGATATAATTACAGGTTTGCCAAGTATTACAACAACAATGGCACAGAGACCCGCACCCTTATTAAAGTATATGGGATCCGAATTGATGTAATAGTGCACGGACAGGCTGGAAAGTTCAGTCTTATTCCCACCATCATTAACCTGGCCACAGCCCTAACATCCATTGGTGTTGGATCCGTGCTCTGTGACTGGATTTTACTGACTTTCATGAACAAGGACCGCACCTACAGCCTTCGGAAATTTGATGAGGTAATTTAG
Protein		Jgi protein >Xetro.A01052.1 LWSYETPKVIVVKNRRLGTIYRLLQLLIVVYFVWYVFVVQKGYQAQETGPESAVITKVKGVSTSKGPRGIKKIWDVAEYVKPPEGGSVFTIITRIESTKLQTMGTCPESRTVPNALCVSDEDCNRGEMHILGNGEQTGRCIIAGRGSLRTCEIYAWCPLEDETAISESLQDYVQNFTILIKNNIHFPQFGFSKGNIEGQGFLRNCTYHPVLSPSCPIFTVGFIVSEAGANFTELAKKGGIIGVIINWNCNLDLHPSKCRPEYSFRRLDLQNKISSGYNYRFAKYYNNNGTETRTLIKVYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSVLCDWILLTFMNKDRTYSLRKFDEVI*

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene
Unigene EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	P2RX2
mouse		MGI	P2rx2	All(2) Targeted, knock Out(2)
zebrafish		ZFIN	p2rx2

Publications
First:		Dopamine and 5-hydroxytryptamine selectively potentiate neuronal type ATP receptor channels. [Eur J Pharmacol 1996]
Most recent:		Salt bridge switching from Arg290/Glu167 to Arg290/ATP promotes the closed-to-open transition of the P2X2 receptor. [Mol Pharmacol 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding ion channel activity receptor activity
Biological:		ion transport
Cellular Component:		membrane
EC:
KOG:

Reagents		tropicalis	laevis
Clones
Affymetrix 1.0		StrEns.2722.1.S1_at
Affymetrix 2.0

Symbol legend[+]

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