aurka Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (150)

Nucleotides (309)

Interactants (153)

XB-GENEPAGE-853081

Gene Symbol: aurka Gene Name: aurora kinase A Synonyms: Aurora-A, btak, stk15, Aurora A, aik, ark1, aura, stk6, stk7, aurora2, pEg2, Eg2, aur-a Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: tpx2(30) , aurkb(28) , cdk1(18) , ccnb1.2(12) , ran(12) , mos(9) , ccnb1(8) View All

XB-GENE-853082

XB-GENE-866460

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016570\|Xenopus (Silurana) tropicalis aurora kinase A (aurka), mRNA CAATCCGGTCTGTGTGAGAGCTGCTAGAGTCCCGGCCCGCACATTCGGCTGCCAGGCACATATAATGGAACGGGCTGTTAAAGAGAATCTTCCTTCTAATGTCAAGGTTTTCCACCCCACAATGGAGGGTCCCAAACGTATCCCAGTTACCCAGCCTCCGAGCACCCAGGTTAGACCTCCTGGGACTGCCGTCTCTGCCCAGAGGATATTGGGTCCCTCCAATGTGCCACAGCGAGTCGTGTCTCAGGCTCAGAAACCTGTTATGTCCGCTCAGAAACCTGTTATGTCCACTCAGAAGCCAATGACTCAGGGGCCACTGAGGCCAGTAACTCATGGGCATCAGGCTGGCAAACCACAGGGACCAAATGAGAATCGTACTCCACAGCAGACCAGCCATTCCTCCACTCCAAACGTGGAGAAGAAAGGAAGCACCGATCAAGGAAAGACTCTGGCTGTTCCCAAAGAGGAGGGCAAAAAGAAACAGTGGTGCCTGGAAGACTTTGAGATTGGGCGCCCCCTGGGCAAAGGGAAGTTTGGGAACGTGTATCTGGCGCGCGAGCGGGAGAGTAAATTCATCCTGGCGCTGAAAGTCCTGTTTAAAACTCAGCTGGAGAAGGCAGGGGTAGAGCACCAACTGCGGAGGGAGGTGGAAATTCAGTCCCATCTCAGGCATCCAAACATCCTCCGGCTATATGGGTACTTCCATGATGCCGCCCGAGTCTACCTAATCCTGGATTATGCCCCCGGCGGGGAGCTGTTCCGAGAGCTGCAGAAAGTCACCAGATTTGATGAGCAGAAGAGCGCCTTGTACATCAAACAGCTGGCAGAAGCCCTCCTGTACTGTCACTCCAAGAACGTGATACACCGGGATATCAAGCCAGAGAACTTGCTGCTCGGTGCCAACGGGGAACTGAAGATCGCTGACTTTGGTTGGTCTGTGCACGCGCCGTCCTCCAGGAGGACCACTCTGTGCGGAACCCTGGACTATCTCCCTCCTGAGATGATTGAGGGCCGAATGCACGACGAGAAGGTGGACTTGTGGAGCCTGGGAGTCCTCTGTTATGAGTTCCTTGTAGGGAAACCTCCATTTGAGACTGACACCCACCAGGAAACCTACAGACGTATTTCAAAGGTTGAATTTCAGTATCCTTCGTATGTATCGGAAGGAGCCAGAGATCTCGTATCGAAGCTGTTAAAGCACAACCCAAACCACAGGCTGTCCCTGAAGGGGGTTCTCGAACATCCGTGGATCATAGATAATTCTGCTCAAAAGCCCAAGAGGAAAGAGGGGCCGGTTACAGGGGCTCAATAGGAAATCCCCTGTGGATCTTTACTTTCCCAAATGTGAGAAGGCACAGCAATTTGCACCTGCTGGATACCCCCCTGCCCTGTTTAATGGGGGGGGGGGGGGGGTCACAATCTGGCAACTCACAGCTCAGTATTTGCTTATTGACTCCAACACAAGGCAATGTACCATGGAACACTCACCGCCTTGCGTGCCTTTTGTGAATGGGACTAGACTGCCTGATCTGGAACGACGGGTTCTTTAAAGGGGCCACGAGGCCCGGTGCTTTATAACTTCTATCGTCACAAACCACTGCTCTGCTACTGGCACAGGTTCCCTTTACTATGGATGTTTAACCCCAGATGCGGCAGTTATAAAACTGTATACGCACTGACAACTAAAATCTGCCGGTTCCGACACCACTGATTGATTATACAGAGATTGTAAGGTTTCCTTGGCCGGTGCAATAGTGATGTGAATGCCTTGGGTATATTTATTAGGCTGCTAATATGGCTGTCCCATTACACAGCTGCTCTGAATACTGAGAGAATGAATTCAGTGTAAATACCTATTCTGTATCAACTTATATCTCGTCTGTCCTTTTATGTGTTAACAACACTTTTTAGAAAAGCATAAAAATCTGTTCTAAGATGCTCCCTTTTCTTTCTGTGTTTTAAAATAAAGCTGATTGAAAAAGTTAAAAAAAAAAAAAAAAAAA	Refseq >NM_001088096\|Xenopus laevis aurora kinase A (aurka), mRNA CGGAGAAGGAAGGAAGTAAGTGGCTGAGCTGCTGGGGGGGAAGACAGAGGTGCGTTCCAGTCGTGTGGGAAGAGGGAGCCTCAGGTTTTTGCGTCTGCAGCTAACCTTGCCTTGCCTCGCCTCGCCTCGCCTCGAACCTAACTATCTGACAGTTGCTACAGACTCGGCCTGCACATTTAGCTGCCAGGCATTCATAATGGAGCGGGCTGTTAAGGAGAACCACAAGCCTTCTAATGTGAAGATTTTTCACCCCATGACTGAGGGAGCTAAACGTATCCCAGTTAACCAGCCGCAGAGCACTCAGTTTAGGCCTCCTGGGACTGCAGTCTCTGCCCAGAGGATATTGGGTCCCTCTAATGTGCCGCAGCGAGTGTTGGCTCAGGCTCAGAAACCTATTCTGTCCAGTCAGAAGCCAACGACTCAGATCCCCCTGCGGCCAGCAACTCAAGGGCATCAGTCCAGCAAACCACAGGGACCAAATGAGAATCGCAATCCACAGCAGACAAGCCATTCCTCCACTCCAAATGTGGAAAAGAAAGGAAGCACCGATCAAGGAAAAACTTCAGCTGTTCCCAAAGAGGAGGGCAAAAAGAAACAATGGTGCCTGGAAGACTTTGAAATAGGGCGGCCCCTGGGCAAAGGGAAGTTTGGAAATGTTTATCTGGCACGCGAGCGGGAGAGTAAATTCATCCTGGCGCTGAAAGTCCTGTTTAAATCCCAGCTAGAGAAGGCGGGCGTAGAGCACCAGCTACGGCGGGAGGTGGAAATTCAGTCCCATCTCAGGCACCCCAATATTCTCCGGCTCTATGGCTATTTCCACGATGCTTCCAGAGTCTACCTAATCCTGGATTATGCCCCTGGTGGGGAGTTGTTCAGAGAGCTGCAGAAATGCACAAGATTTGATGATCAGAGAAGTGCCATGTACATCAAACAGCTGGCAGAAGCCCTCCTGTACTGTCACTCCAAGAAGGTGATACACAGGGACATCAAGCCAGAGAACTTGCTGCTTGGCTCCAATGGAGAACTGAAGATCGCCGACTTTGGCTGGTCTGTGCATGCTCCATCCTCCAGGAGGACCACTCTGTGTGGAACACTGGACTATCTACCTCCTGAGATGATCGAGGGCAGAATGCATGATGAGACGGTGGACTTGTGGAGTCTGGGAGTTCTCTGTTACGAATTCCTCGTAGGGAAACCTCCGTTTGAGACTGACACCCACCAGGAAACCTACAGACGTATTTCAAAGGTTGAATTTCAATATCCGCCATATGTATCGGAAGAGGCAAGAGATCTTGTCTCAAAGCTGTTAAAGCACAACCCAAACCACAGGCTGCCACTGAAAGGGGTTCTCGAACATCCATGGATCATAAAAAATTCTCAACTCAAGAAGAAAGACGAGCCCCTTCCAGGCGCCCAATAGGAAATCTCCTGAGGCTCCGACTCTCTTCCCAAATGTGAGAAGGCATAACCGTTTGCACCTGCTAGATAACGCCTCTTATTTTTAATTGGGAGGTGGCTAATCCTTCCAAAAGTGAGGGGTGATCATGATCTGGCAACTCATTGCTCAGTATTTGCTTATTGACTCAAACACAAGGCAATGTACCACGGAACACTCAGTCTTATGTGGCTTCTGTGAAAAGGACTGATCTAGATTTGGAACAACGGGTTCTTGCAAGGCCTGGTGCTTAATTTCCACTGCTCTGCTGTTGGCACAGGTTCTCTTTATATCTTGAAGGATATTTTTACACAGACCCGGCAGTCTGTATATGCACTGAGAACTGTAAAATCTGCTATTTCCGACTGCTACAACAAGCAAGTTATTCTCTACTGAATGCTGTAATATACGGAGATTCTGAGGTGCAATAGCGATATGAATACCTGGGTATATTTATTAGGCTGCTAATATGGCTGTCACCGTACAACGCTACTTGAATACTGAGTGAATGAACGAATGTAAATACATATTCTGTATTAATTTCGTATGTCCTTTTATATGTAACACTTTTTAAAAAGGCAAAAAATCTGTTCTAAGATGTTCCTTTTTTTTTTTTTTCTTCTTCTGTTTAAATGTTTTAAAATAAAGCTTTGATTAAAAAGAAAAAAAAAAAAAA
Protein		Refseq >NP_001016570\|aurora kinase A [Xenopus (Silurana) tropicalis] MERAVKENLPSNVKVFHPTMEGPKRIPVTQPPSTQVRPPGTAVSAQRILGPSNVPQRVVSQAQKPVMSAQKPVMSTQKPMTQGPLRPVTHGHQAGKPQGPNENRTPQQTSHSSTPNVEKKGSTDQGKTLAVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKTQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDAARVYLILDYAPGGELFRELQKVTRFDEQKSALYIKQLAEALLYCHSKNVIHRDIKPENLLLGANGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPSYVSEGARDLVSKLLKHNPNHRLSLKGVLEHPWIIDNSAQKPKRKEGPVTGAQ	Refseq >NP_001081565\|aurora kinase A-A [Xenopus laevis] MERAVKENHKPSNVKIFHPMTEGAKRIPVNQPQSTQFRPPGTAVSAQRILGPSNVPQRVLAQAQKPILSSQKPTTQIPLRPATQGHQSSKPQGPNENRNPQQTSHSSTPNVEKKGSTDQGKTSAVPKEEGKKKQWCLEDFEIGRPLGKGKFGNVYLARERESKFILALKVLFKSQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDASRVYLILDYAPGGELFRELQKCTRFDDQRSAMYIKQLAEALLYCHSKKVIHRDIKPENLLLGSNGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDETVDLWSLGVLCYEFLVGKPPFETDTHQETYRRISKVEFQYPPYVSEEARDLVSKLLKHNPNHRLPLKGVLEHPWIIKNSQLKKKDEPLPGAQ UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.25531	Xl.124 [+] Xl.58545 Xl.58615
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		8 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tegg021k02

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	AURKA	OMIM:114500
mouse		MGI	Aurka	All(5) Targeted, knock Out(1) Targeted, other(3) Gene Trapped(1)
zebrafish		ZFIN	aurka

Publications
First:		Degradation of a developmentally regulated mRNA in Xenopus embryos is controlled by the 3'' region and requires the translation of another maternal mRNA. [Mol Cell Biol 1991]
Most recent:		The Role of NEDD1 Phosphorylation by Aurora A in Chromosomal Microtubule Nucleation and Spindle Function. [Curr Biol 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding protein kinase activity protein serine/threonine kinase activity More[+] protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:
EC:
KOG:		[D] Serine/threonine protein kinase

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.25531.1.S1_at [+] Str.47564.1.A1_x_at Str.47564.1.A1_at	Xl.124.1.S1_at
Affymetrix 2.0			Xl2.124.1.S1_at

Symbol legend[+]