Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (966) GO Terms (82) Nucleotides (271) Proteins (68) Interactants (2496) Wiki
XB-GENEPAGE-478788
???displayGene.symbol???:
 tbxt

???displayGene.name???: 
T-box transcription factor T

???displayGene.synonyms???
bra , brachyury , ntl , t , t-a , t-b [+] ( Nomenclature history )

???displayGene.geneFunction???
T-box transcription factor,. Ortholog to the murine brachury or T gene, mutations in which cause defects in tail development. Immediate-early transcriptional response to mesoderm induction.

Protein Function :
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Causes dorsal mesodermal differentiation of animal cap ectoderm when co-expressed with wnt8 and ...[+]


InterPro :
T-box sf, p53-like TF DNA-bd, TF T-box CS, TF T-box, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


MIM:
NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO; NTD [+]

External Links:
GEO Series :
GSE48663, GSE96655, GSE122551.
1/6
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tgas116l23      


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info