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XB-GENEPAGE-493882
Gene Symbol:
wdr5
Gene Name: WD repeat domain 5
Synonyms:
xwdr5
,
swd3
,
big-3
,
wdr5-a
,
wdr5-b
( Gene Function: WD40 repeat-containing protein Protein Function
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Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation a...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID
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XB-GENE-493883 | XB-GENE-6255108 | XB-GENE-866297 | |||||
Gene Symbol | wdr5 | wdr5.L | wdr5.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
496891
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446809
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447447
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | wdr5 | wdr5.L | wdr5.S | |||||
Orthology ![]() |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development., Cell 2005 ![]() |
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Most Recent |
Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Genesis 2021 ![]() |
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All | View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 10 terms | 0 term | 0 term | |||||
PANTHER | wdr5 | |||||||
KEGG Pathways | K14963 | K14963 | K14963 | |||||
KOG |
[R] WD40 repeat-containing protein
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | wdr5 | |||||||
Antibodies | wdr5 Ab1 | |||||||
Morpholinos | wdr5 MO4 | wdr5 MO1 , wdr5 MO2 , wdr5 MO4 | wdr5 MO1 , wdr5 MO2 , wdr5 MO4 | |||||
ORFs | wdr5 ORF1 | wdr5.S ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



