ache Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

My Xenbase
[Login] [Register]

Search

Summary

Gene Literature (95)

Nucleotides (73)

Interactants (38)

XB-GENEPAGE-923159

Gene Symbol: ache [provisional] Gene Name: acetylcholinesterase [provisional] Synonyms: acetylcholinesterase, arache, n-ache Add Xenopus synonyms Gene Function: degradation of neurotransmitter acetylcholine Interactants: bche(9) , ace(3) , colq(3) , nr5a2(3) , gnpda1(2) , got1(2) , gpi(2) View All

XB-GENE-923160

XB-GENE-923165

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002940042\|PREDICTED: Xenopus (Silurana) tropicalis acetylcholinesterase-like (LOC100490673), mRNA TCTCTGCCTCCCTAGGTAATCCCACAGAGGAGCGGCCATGGCACTTGTACCCATTGCTCAGCTGTGCCTCTGCACACTCTCTCTCCTCCTGGTTCCTGCGCTCACACAGAGCGATGGCGGTCTCCTGGTCAGCACTCGTTCGGGGAAAGTGCGTGGCCTGAGGCAACCTGTCCTTTCTACCCATGTAAGTGCCTTCCTGGGCATTCCCTTTGCCGAACCACCGGTGGACAAAATGCGCTTCCGACGTTCGGAGCCCAAGAAACCATGGACAGATGTTTGGGACGCGACAGCCTACCCTAATGCCTGCTATCAATATTTTGATACTTTGTATCCTGGTTTCCCTGGCATGGAAATGTGGAATCCCAACCGGCCAATGAGCGAAGATTGCCTGTATCTTAACATCTGGGTCCCCCACCCACGTCCCTCCAATGCTACCGTTATGGTATGGATATATGGTGGAGGTTTCTACAGCGGCTCCTCTTCTCTCGACGTTTATGATGGACGCTACCTGTGCCATGCTGAGAATGTCATTGTGGTCTCCATGAATTACCGCGTTGGAGCTTTTGGTTTTCTGACCCTGACACCGGGTAGTGTAGATGCCCCTGGCAACGTTGGCTTGTTTGATCAGCGTCTTGCTCTCCAGTGGGTTCAGGACAATATCGCCTTCTTTGGTGGAGATCCCAGGACCGTCACAATTTTTGGGGAAAGTGCCGGAGCTGTCTCCGTGGGTATGCACGTCCTTTCCCCTGGAAGCCACCATCTCTTCTCCAAGGCTGCCTTGCAAAGTGGCTCACCCAACACGCCCTGGGCTACAATCACCCCACAAGAAGCTAGGCGCCGCACAGAGCTCCTGGGAAAGTTTTTGGATTGCAGAATGGGAAATGATACAGAGTTACTGAACTGTCTAAGAGTCAAGCAACCGCAGGAATTAATTGACCATGAATTCTCTGTACTTCCAGCCCCCAGTGTCTTTCGTTTTGCCTTCGTACCGGTGCCAGACGCAGACTTTTTCCCAGAGCCTCCTGAGATCTTGATGAATATGGGCAGATTTAAGCCTTGCCCCTTGATAATGGGAGTCAACCAGAATGAAGGATCGTACTTTCTGTTGTATGGGGCCCCTGGCTTTAGCAAGAACAACGAGAGCCTCATCACTCGAGAAGAGTTCCTCGGTGGGGTCAAGATGAGTGTTCCACAAGCCAACGACATTGCCCTGGAGGCGGTAGTGATGCAGTACACAGACTGGGCAGATGAACATGCTGGGGTCAAGAACAGAGAGGCCATGGACCAGCTGGTGGGAGACCATAATGTCATTTGCCCCCTCACTTATTTTGCCGGGAAGGTTGCTGAGACCGGAAACCGGGTGTATACTTATTTCTTTGACCACCGGGCGTCCAACCTGGCTTGGCCGCAGTGGATGGGGGTCCCACATGGATACGAAATTGAATTTGTCTTCGGCCTTCCCCTGGATGCAAATTTGAACTACACCCCCCAGGAAGAAGCTCTGAGCCGCAGGATGATGAGATACTGGGCTAACTTTGCACGGACTGGTGACCCAAACGAGGGCAACGACGCCCACCAACCGCGCTGGCCCTTGTACACGGCCTCTGAGCAGAGGTATATGGCCCTCAATAACAAGCCATACCAGGAGCTGCAGGGTATCCGAGTCCAAACGTGTATGTTCTGGAACCGCTTCTTGCCTAAACTGCTCAACATCACAGACAATATAGATGAGGCCGAGCGGCAGTGGAAGGTGGAGTTCCATCGCTGGAGCACCTACATGATGCGGTGGAAAAACCAGTTCGACCATTACAGCAAGCAGGAGCGCTGCAGCGAGCTGTGACCTCACTGTGACATCACTGTGACATCACCCCGCCATTAGAAGCCACGGAACTGTAGCGAGACGCGCAGTGACAACGTTGACG	Refseq >NM_001127860\|Xenopus laevis acetylcholinesterase (ache), mRNA GAGAGACAGGATCGCAGCCTGCCCAGGTAATCCCACAGAGGAGCAGCCATGGCACTTGTACCCTTTGCTCAGCTGTGCCTCTGCACATTCTCTCTCCTCCTGTCCCCGGCTCTCACACAGAGCGATGCTGGTCTCCAGGTCACTACTCATTCTGGGAAGGTGCGTGGCCTCAGGCTTCCAGTCCTTTCTAGCCAAGTAAGTGCCTACCTGGGCATTCCCTTTGCCGAACCACCAGTGGACAAAATGCGCTTCCGACGTTCAGAACCCAAGAAACCATGGACAGATGTTTGGGATGCAACCGCCTATCCTGATGCCTGCTATCAATATTTTGACACTTTGTATCCTGGTTTTCCTGGCATGGAAATGTGGAATCCTAACCGGCCAATGAGTGAAGATTGCCTATATCTTAACATCTGGGTACCACATCCACGTCCCTCCAATGCTACCGTTATGGTATGGATATATGGTGGAGGTTTCTACAGTGGGTCTTCTTCCCTTGATGTTTATGATGGACGCTACCTGTGCCATGCAGAAAATGTCATTGTGGTCTCCATGAATTACCGCGTTGGAGCTTTTGGTTTTCTGACCCTGACACCCGGTAGTGTTGATGCTCCTGGCAATGTTGGATTGTTTGACCAACGTCTTGCTCTCCAGTGGGTTCAGGACAATATTGCTTTCTTTGGTGGCGATCCCAGGACTGTCATGATTTTTGGGGAAAGTGCTGGTGCCGTCTCTGTGGGTATGCACGTTATTTCCCCTGGAAGCCACCATCTCTTTTCCAAGGCTGCATTGCAGAGTGGCACACCCAACACACCCTGGGCTACAATCACCCCACAAGAAGCTAGACGCCGCACAGAGATGATGGGAAAAAAATTGGACTGCAGAATGGGAAATGATACAGAGTTATTGAACTGTCTAAGAGCCAAGCAACCCCAGGAATTAATTGATCATGAATTCTCTGTCCTTCCAGCACCCAGTGTCTTTCGTTTTGCCTTTGTGCCGGTGCCAGATGGAGACTTTTTTCCAGAGCCTCCTGAGGTCTTGATGAATATGGGCAGATTTAAGCCATGCCCCTTGCTGATGGGAGTCAACCAAAATGAAGGCTCATACTTCCTACTGTATGGGGCCCCTGGCTTTAGTAAGAACAACGAGAGTCTCATCAATCGAGAAGAGTTCCTCGGTGGGGTCAAGATGAGTGTTCCACATGCCAACGATATTGCCCTGGAGGCAGTAGTGATGCAGTACACAGACTGGGCAGACGAGCATGCAGGAATCAAGAACAGAGAGGCCATGGATCAGCTGGTGGGAGACCATAATGTCATTTGCCCCCTCACTTATTTTGCCGGGAAGGCCTCAGAGACTGGAAACCGGGTGTATACTTATTATTTTGATCACCGGGCATCCAACTTGGCTTGGCCACAGTGGATGGGGGTTCCACATGGATACGAAATTGAATTTGTCTTCGGTCTTCCCCTAGTTGCAAATCTGAACTATAACCCACAGGAAGAGGCTCTGAGTCGCAAGATGATGAGATATTGGGCTAACTTTGCACGGACTGGTGACCCTAACGAGGGTAACGATGCCCGTCAACAGCGTTGGCCCTTGTACACTGCATCCGAGCAGAGGTATATAGCACTTAACAACAGGCCACAACAGGATCTGCAGGGCATCCGAGTCCAAACGTGCATGTTCTGGAATCGTTTCTTGCCTAAACTGCTCAACATTACAGACAATGTTGATGAGGCTGAGCGGCAGTGGAAAGAGGAGTTCCATCGCTGGAGCACCTACATGATGAGATGGAAGAACCAGTTTGACCATTACAGTAAGCAGGAGCGATGCAGCGAGCTGTGACCTCACTGTGACATCACCCTACAACCAGCCGTAGAAGCCATGGAACTGTAGCGAGACGTGCAGTGATAACAACATCCTCGTGAGATCACTGGGCAACGTCTTCGCTTTCAGGAAAGCAGAGCCACTGTAGCAGCTTGTGACGTCATTATGACAGCACAGTGATGTCACAGCGGAGATACATTTCAGCATTGCTGCCATAACATTGAAACACAATTACACGCACCATCATGTGACTAATGCTAATACCCTGTACTGTACAAATCCTCCGCAGGGGGTGTTTCCTGTCATTCGCTATTGTCCCTCGCATGTCCATTTGTATAAAGTGTTTGTTGATAAGATATAAATATATATATGCATATTTATAATATATAGAGAGACAGAGGGAAACCTACTTGTATTTTATTTATTTGTGATGCCATAAATGTCTGACCTCAAAGAAAACTTTTCACTAGATGCCAAATATATCCTAAATGTGCAATATAATGTGAGCAATCATGTGGACACCATGAATTTTATATTCACCCTACTGTACTGTATATTGTTTTAGAGAGCTTTAATCCAATCTATAACATTGTGTGTTTTGCTTACACTACTAAACAACTCTTAGAATGTGTATATGTTGTGTATGAATCTATACTGAACCACTCCAGGAACAAACCTATGTAGATACCCCATCTAGAGTCCACTTCTCGCCAGGGACAATCCTATAGCTTATAGCAGCACCAGGTTGACCCCACTAATTGCTTGGAACAATCCCACGAAGCAACGCTGGGTTGACTGCACCCAATCCAATGCGGCCAACCCTTTTAGATTCCACTGCTTGCTTTGAACAATCCTATTGAGCCAACCCATTTAGAATTGACTGCTAGTATAGAACACTGTTATGTAGACCATCCATATTGAATTGTTACCAATACATATATATCACTTGGGTGTTCCTTTAGCTGAAACCCATCACCTCCATTCAAGCCCTGAGTAAATATACTTAACATCCAAACTTTTTATATAGTTGCATCGTTCAAAATAGTATATAGTCCATTTGCCAAACTGCATCTTCCCGCATTCTCCACCAAAGCAGCCAAGGATACAGAACATGATGTTATTTTGTGTTACGATATGGCATGATATGGTTATGTAAATGACTAAATGCATCCTTACAATTAACACTCATACTAGCCTGTGCCAGTGATTTGGGGTTACCTATTATACAGAGGTGTAGTAGCTCCAGGAGTGCCTACTGATCTAGTAATTTAGAATGTTATGCCTAACTTTTAACATACTGATCCAGCATTCAGCAAGTATTTTATGCCTGTACTAATCCAATAACAACATACTTATTCTTCTATATACTGCTGTATCCATCTCATACCTGCCCTTCACTAGAATGGTCCATTAACAGAGAATGTTAACTATCCTTTAATATTTGAATGCAGTAACAGACTAAATTATAACTCTGAAGAGTTTCATTCATCCAGGTCATGGTATATCTAATATGGGTAGTTCTAGTACGGCTGGACTTGTTGAGTGATCGATGGGGACGTTTCGCTGCTCATCCGGGCAGCTTCTTCGGTTCGGCTGGCTGGTGTGGGGGGTTCTCGGCGTGTAAACTCTTCCACTAATCCAATCACAATGGCACATTGTAACTCTTCAGTGAGGTGACTTCTGAAATCCGTGGATTGGTGGAGGAGTTTGTGTGCCGGGGACTTCCCACGCCGGTCGGTTGGGCTGGGGAGGCTGCTCGGGTGGGTGGTGGAGCGTCTTCATTGATTGCTCGGCAGGTCCAGTTGTTTTGGAAATACTTATATTAGAGAGACTAAATTATACCTACCCTATTGTATTTTATCTCCCTATTAATATGCTGCTCCATCAACTATATTATAGCTATCTTTTAGTATACTTCAACTGAGTATGTTTCAACCCAAACCCATTAAAATACTGTTCTAATAACACAGTATGTTATACCTACCCTTTAAAATACTGTTCTACCAAATGAGTATGTTATATGTACCCTTTAATATATTGTTCCACCAACTGAGTATGTTATACCTACCCTTTAATATATTGATCTACCAATTGAGTATGTTATACCTACCCTTTAATATACTGTTCCACCAACTGAGTATGTTATATCTACCCTTTAATATATTGTTCCACCAACTGAGTATGTTATACCTACCCTTTAATATATTGATCTACCAACTGAGTATGTTATATCTACCCTTTAATCTGCTGTTCCACCAAGTACAGCACTGTATTTGCTAATAACTAAATGTGTATATATGTGTATTATGCTCACTCTAGAATACAAATCATAACAGAGTCAAGCTAAGCTGTGACCCTTCAGCTGTTTTTGAACTACACCTCCCAGCAAGGCAGCTGTGTTTTATTTCAGGGATGTTGGGAGATGTAGCTGAACTATAATGATAGAGGCAGAGTGACTGTCTCATAACAGGCCAAGATCAATGACATCAATATTCATGACTGTGTATGAGGATGATGGTTGTTGCCCTTTAACAAATTATATGTACAAAGTGTGGTCTGTAGAGAGTAAGTACATATTCTATGTTCTATGTGTATTGTTATCCAGTATATATATATATATATATATATATATATATATATATATATATATATTAGTCTCTCTGTTCTTAGAGTATGTACTAAATGCTGTTACTCAGTTTATGAGACCTCTATCATCAGGGGGAACCGGCTACTGAAACTGAGAATTTCTTCCATTCTCCTCCATTCTCTTATTGGCAAGGTCAGCGGTCAATATAAATGGCTCCCCCTAAATCGACCATAAACCGTGGTGTGGTTTAAGCTCTCCACTCCTGGACCTGCCCTTTAGTAAGTGGAGTGGGACCAGACACTAGGCTGTTGTATTGCATGTGTGAGAAAGAAGAATAAAGTTGTATCTGCAACAATCAATAAATGAAGAGTAAACCCCAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002940088\|PREDICTED: acetylcholinesterase-like [Xenopus (Silurana) tropicalis] MALVPIAQLCLCTLSLLLVPALTQSDGGLLVSTRSGKVRGLRQPVLSTHVSAFLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPNACYQYFDTLYPGFPGMEMWNPNRPMSEDCLYLNIWVPHPRPSNATVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVTIFGESAGAVSVGMHVLSPGSHHLFSKAALQSGSPNTPWATITPQEARRRTELLGKFLDCRMGNDTELLNCLRVKQPQELIDHEFSVLPAPSVFRFAFVPVPDADFFPEPPEILMNMGRFKPCPLIMGVNQNEGSYFLLYGAPGFSKNNESLITREEFLGGVKMSVPQANDIALEAVVMQYTDWADEHAGVKNREAMDQLVGDHNVICPLTYFAGKVAETGNRVYTYFFDHRASNLAWPQWMGVPHGYEIEFVFGLPLDANLNYTPQEEALSRRMMRYWANFARTGDPNEGNDAHQPRWPLYTASEQRYMALNNKPYQELQGIRVQTCMFWNRFLPKLLNITDNIDEAERQWKVEFHRWSTYMMRWKNQFDHYSKQERCSEL	Refseq >NP_001121332\|acetylcholinesterase precursor [Xenopus laevis] MALVPFAQLCLCTFSLLLSPALTQSDAGLQVTTHSGKVRGLRLPVLSSQVSAYLGIPFAEPPVDKMRFRRSEPKKPWTDVWDATAYPDACYQYFDTLYPGFPGMEMWNPNRPMSEDCLYLNIWVPHPRPSNATVMVWIYGGGFYSGSSSLDVYDGRYLCHAENVIVVSMNYRVGAFGFLTLTPGSVDAPGNVGLFDQRLALQWVQDNIAFFGGDPRTVMIFGESAGAVSVGMHVISPGSHHLFSKAALQSGTPNTPWATITPQEARRRTEMMGKKLDCRMGNDTELLNCLRAKQPQELIDHEFSVLPAPSVFRFAFVPVPDGDFFPEPPEVLMNMGRFKPCPLLMGVNQNEGSYFLLYGAPGFSKNNESLINREEFLGGVKMSVPHANDIALEAVVMQYTDWADEHAGIKNREAMDQLVGDHNVICPLTYFAGKASETGNRVYTYYFDHRASNLAWPQWMGVPHGYEIEFVFGLPLVANLNYNPQEEALSRKMMRYWANFARTGDPNEGNDARQQRWPLYTASEQRYIALNNRPQQDLQGIRVQTCMFWNRFLPKLLNITDNVDEAERQWKEEFHRWSTYMMRWKNQFDHYSKQERCSEL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.8415 [+] Xl.26362
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	ACHE	OMIM:112100
mouse		MGI	Ache	All(8) Targeted, knock Out(5) Targeted, other(3)
zebrafish		ZFIN	ache	9 Lines(s)

Publications
First:		The distribution of monoamine oxidase and acetylcholinesterase in the brain of Xenopus laevis tadpoles. [Z Zellforsch Mikrosk Anat 1973]
Most recent:		RIC-3 differentially modulates alpha4beta2 and alpha7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation. [BMC Neurosci 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		acetylcholinesterase activity catalytic activity cholinesterase activity
Biological:
Cellular Component:
EC:		acetylcholinesterase
KOG:		[T] Acetylcholinesterase/Butyrylcholinesterase

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.4889.1.S1_at	Xl.26362.1.A1_at [+] Xl.26417.1.A1_at Xl.8963.1.A1_at
Affymetrix 2.0			Xl2.26362.1.A1_at [+] Xl2.26417.1.A1_at Xl2.51738.1.S1_at Xl2.8963.1.S1_at

Symbol legend[+]