fas Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-940177

[provisional- machine annotated only]

Gene Symbol: fas [Predicted: Source is Human Entrez Gene]

Gene Name: Fas (TNF receptor superfamily, member 6) [Predicted: Source is Human Entrez Gene]

Synonyms: alps1a, apo-1, apt1, cd95, fas1, fastm, tnfrsf6 Add Xenopus synonyms

Gene Function:

Interactants: casp8(5) , fadd(5) , tnf(4) , c9orf3(2) , casp10(2) , casp3(2) , cd40(2) View All

XB-GENE-940178

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1
	Entrez Gene
mRNA	Refseq >NM_001102729\|Xenopus (Silurana) tropicalis Fas (TNF receptor superfamily, member 6) (fas), mRNA TCCCTCTCAGTCTCTCAGTGGCTGACAAGATGTTATTGCCTTGGATCTGCCTATTCATTGCCCTGGCAGCTGAAAGGAACTCTGCATCTGCAATAAATAATATAGGAGATACCTCACCCGCATACACTGGGAAACCGTCAGCGCCACTGCGTAGGTTTTTTAAAAGAGAATTAAAATGTGAAGATGGGGAATATCCTGGAAATCAATATTGCTGTAAGAACTGTCCAGCTGGGACCTACGTAGAGAACGACTGCCAGGAGAATCATCAGAAACCCAACTGCCAGCCTTGCACTGATGGAAAAGATTACATGGACAAACCCAATGGATATCATCAGTGCCTCCTCTGCAAACGCTGTGACCCGGAACAAGGAGAGGACGTTCATTCTCCTTGCACAGTCTTCCGGAATACAGTGTGTAAATGCAAAGTCAATTTTTTCTGCGGAACCAACTCCACCCAAGACCCCAGGAGCTGCGATCACTGCCAGCCGTGCACTCAATGTGAGAAAGGCGTTGCTGAGAGTTGCACGGAGACAAGAGACACAGTGTGCAACAAAGGGAGTCGGTACCGCTGGGGGTTGCTAGCAGCTCTGATACTAGTGGCTGTGGGTGCAGGTTTGCTGTGTGTAAGATGCAGACAAAAACCCAGGCCCATATACCAGCCTCCAACACTGACTCCCCTAGTCAAGCCTTATCCTTCACACCTTGAAGATATTGATTTAGAAACTCCTCTACAAGACCTGGCGGACATTATGCTGCATGACGACGTGGTGAAGTGTGTCAGGAGAATGGGCCTCTCCAACCCTACCATAGATGACATTAAAAACACCAATGGACAAGGCCGCGAAGGAAGGTACCAGTTGCTTAGAAGTTGGTATGTGCAATACGGGCAAATGGGGGCACTTCGGCACCTCATCAAAACTCTCCGAGACCAAGGCCTCAACAAACCCGCAGACGACTTCATCGATATCTTAAATAGAAGAGTGCAGCCCTAAGGAGAGACCGCAAAAAAGGTGACGTTCATGGACTATTGACTGTGGGCATCTTGATTATGAGTATGGGTGCTCCATTATAGAGAGGAGGACAACAGTGGCTGCCACAGTGGGCACCATGATGTTTGTATATAAATGGAAACTGCAATGATGCATCCCATGTTGTATTCATAGTGTAAATATGAGCAACATTTCCACTAACCACGGCCCATAGGACAAAGTGGACGGGAGAAGAATGTTGACGTTTACTAGAGTATAAGTATCATTTACAAATGAATTTGCCTGTATATAGTGGGTGAGGGGTTGAAGAACGGATGTTGTTGGGGGTTTGCTTATTGAGAACAGGACCAAAGGGAACCTCACCATATGCACCTTCTCAGCCATAGGGCAAGGAGAGAACGTTCTCCACCTGAAGGGCTGGCGGGGAAGGATACCAACTCCTGGAAACTTGCCTCTGTACAGGAGAAAGCAGGAGTGTTCTTGCACCAGCAAATACCAGCTGACCCCCTAGAGAAGAGTAGGTATGGAGACTGGAGGATGGACAGGTTCCATGGGGGCACAATGACTTATCCCTACTACCTAAAACCTGGTATACAAGGAAAAGGTACAGTGAGGGGCATGAAGGCTACGGTAGGCCGTCCAGAACAATTTGTATATCCCCAAATACGAGAGCAGAATTGCTTGAGATGGTGGGAAGGTGCATTTCCTGGGCACATAATTGTACTTCCTTCCTGTGAAAGTCACACATTCCTTCCATGCTTTATGGCTTGTATTCCCCCAAGACTGGTGCATTGGTCCTTGATCATCTACATGATCCTACAGGGCTCATTAGTTTAGTTTCAAACTTAGAAGAGGAATAGAATTACAAAGAGACCAACCTGTAGCCAAAAAGAGCACTGGAATGTACATTAAGGCAGACCAGCCTGTAGCCAATAAGAGCACTGGAATGTATATTAAGCCAGACCAACCTGTAGCCAATAAGAGCACTGGAATGTACATTAAGCCAGACCAACCTGTAGCCAACAAGAGCACTGGAATGTATATTAAGCCAGACCAATCTGTAGCCAATAAGAGCACTGGAATGTATATTAAGCCAGACCAACCTGTAGCCAATAAGAGCACTGGAATGTATATTAAGCCAGACCAATCTGTAGCCAATAAGAGCACTGGAATGTACATTAAGGCAGACCAGCCTGTAGCCAATAAGAGCACTGGAATGTATATTAAGCCAGACCAACCTGTAGCCAATAAGAGCACTGGAATGTATATTAAGCCAGACCAACCTGTAGCCAATAAGAGCACTGGAATGTACATTAAGCCAGACCAACCTGTAGCCAATAAGAACAATGACATTTTGCTGGAGCTACCCCAACCCATCGGCCGTTACATAGGATTTCCCATAGAAATTCTCTAGTTTTGCTCAGGGAGACAGGCCGTATAAAGCCTGTTAGTAGCAGGGGATCTATTATACATAATGCTCAGGGAGTGTACAGATCTGGGATAACTTGAACACCAATCTCTAGAACAAAGTTTTTTATTTATGTGAAACAGATGTGCCATAATGTATTTGGTACCTACAGAAATAAACTTATTTTCCAATACTGTTA
Protein	Refseq >NP_001096199\|Fas (TNF receptor superfamily, member 6) precursor [Xenopus (Silurana) tropicalis] MLLPWICLFIALAAERNSASAINNIGDTSPAYTGKPSAPLRRFFKRELKCEDGEYPGNQYCCKNCPAGTYVENDCQENHQKPNCQPCTDGKDYMDKPNGYHQCLLCKRCDPEQGEDVHSPCTVFRNTVCKCKVNFFCGTNSTQDPRSCDHCQPCTQCEKGVAESCTETRDTVCNKGSRYRWGLLAALILVAVGAGLLCVRCRQKPRPIYQPPTLTPLVKPYPSHLEDIDLETPLQDLADIMLHDDVVKCVRRMGLSNPTIDDIKNTNGQGREGRYQLLRSWYVQYGQMGALRHLIKTLRDQGLNKPADDFIDILNRRVQP

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI UCSC

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.29735
Unigene EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	FAS	OMIM:134637 OMIM:601859
mouse	MGI	Fas	All(11) Targeted, knock Out(2) Targeted, other(6) Spontaneous(2) Chemically Induced(1)
zebrafish	ZFIN	fas

Publications
First:		Craniofacial malformation in Xenopus laevis tadpoles caused by the exposure of early embryos to ethanol. [Teratology 1983]
Most recent:		Apoptotic and survival signaling mediated through death receptor members during metamorphosis in the African clawed frog Xenopus laevis. [Gen Comp Endocrinol 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		receptor activity transmembrane receptor activity
Biological:		apoptosis immune response signal transduction
Cellular Component:		membrane
EC:
KOG:

Reagents	tropicalis	laevis
Clones	open biosystems
	geneservice/RZPD imagenes
Affymetrix 1.0	StrJgi.2144.1.S1_at [+] Str.29735.1.A1_a_at Str.29735.1.A1_at
Affymetrix 2.0

Symbol legend[+]