Gene Symbol: cdc25c Gene Name: cell division cycle 25C Synonyms: cdc25, xcdc25c Add Xenopus synonyms Gene Function: M-phase inducer phosphatase Interactants: rasgrf1(105) , cdk1(104) , pold1(83) , ccnb1.2(59) , plk1(30) , mapk1(27) , wee1(21) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		NCBI Nucleotide >BC159061|Xenopus tropicalis cell division cycle 25 homolog C, mRNA (cDNA clone MGC:147895 IMAGE:7554066), complete cds GTTTTTTTTTGCTACGTTGTATCTGTAACTGGTATCGTAGTAGGGGTTCGAATGGTAAAATAAAAGTGCACGCAGATGCTGTAGGGGTAGAAGGGTGTTCTGGACACATGATAACTTGCTTCAGACGCAGACTACTTGGCGATGGAGAGTCGGTTCGATAATTAAGGAGCGTGTAACCCCCGAATGTTCCAGACAAGTAGTGGAGGCTCGGCTGAAGTCATGGCAGAGAATCACATAATGTCATCAGAAGCACCCCCAAAGTCCAACCAAGGCCTGCATTTCCGTACAAATTGCAGAATGATATTAAACCTCCTTCGTGAAAAAGATTCCTCAGTTACATTTTCTCCTGAACAGCCTTTGACACCTGTCACTGACCTTGCTGTTGGATTTAGTAACCTAAGTACCTTCACTGGTGAAACTCCCAAACGCTGCCTGGACTTGTCCAACCTTGGTGATGAGACTGGGCCACTGCCAACAGAGTCCCCTGACAGAATGTCATTAGGCAAAGTGGAGTCACCAAAGACACAATTTGTCCAGTTTGAATTTACGCCAGATCTAGGATGCAAAGCCAAAAAGTGTCAGAGAGGAAACATGAATTCTGTTCTGCCTCGCCTTCTTTGTAGTACTCCAAGTTTTAAAAAGACCTCAGGAGGACAGAGAAGCATGTCCAATAAGGAAAATGAGAGTGAATTGTTTAAAAATCCAAACTGCAAACCTGCTGCTTTGGTGCTGCCACAAGAAGCAGTCGATTCACAATTCTCTCCAGCACCAGAGGACAAGGTTGATATCTCCCTAGACGAGGATTGTGAGATGAATATCTTGGGTTCCCCAATAAGTGCAGCTGCCCCTTGTTTGGAGGGACCACATGATGACATCAAAATGCAAAATCTTGATGGATTTGCAGATTTTTTTTCAGTTGATGAAGAGGAGATTGAGAATCCCTCTGGAGCTGTTGGTAACTTGTCCTCTAGCATGGCAATTCTTCTGTCAGGACCTCTTTTAAATCAAGAAGTAGAAGTCAGCAATGTAAACAATATATCTTTAAACAGAAGCCGTCTTTACCGCTCACCATCTATGCCAGAGAAACTTGACAGGCCGATGCTTAAACGCACAGTGAGGCCACAAGACAGTGAAACACCTGTCAGAATTAAAAGGAGACGCAGTACCAGCAGCCCCCTTCAACCTGAGGAAGAGAACTGCCAACCAAGGAGGAGGGGTACATCTCTTAAAAAGACACTTTCTCTTTGTGACGTGGATATTAGCACAGTTTTGGATGAAGACTGTGGTCACAGACAACTTATTGGAGATTTTTCAAAGGTTTATGCTTTACCCACTGTAACTGGCCGACACCAGGACCTCCGCTACATCACTGCAGAGACTCTGGCAGCCTTAATTCATGGAGACTTCAGCAGTTTAGTGGAGAATGTCTTTATAATAGATTGTCGTTATCCTTATGAATATGACGGCGGGCACATCAAGGGTGCATTAAACCTCCACCGGCAAGAGGAAGTAACTGACTACTTCCTGAAACAACCTCTGGCTCCATCGGTGGCACAGAAGCGATTAATTATAGTTTTTCATTGCGAGTTCTCTTCTGAAAGAGGCCCAAAAATGTGTCGCTTCCTTAGGGAGGAAGACAGAGCCAGGAATGAGTACCCAGGCTTGTATTACCCAGAGCTTTATCTCCTTAAAGGCGGTTACAAGGATTTTTTTCCTGAATACAAGGAGCTATGTGAGCCACAGGGCTACTGCCCAATGCACCATCAGGATTTCCGGGAGGAGCTTCTGAAATTTCGGACAAAATGTAAGACATCAGTTGGTGATAGAAAGAGAAGGGAACAGATTGCCCGCCTGATGAAGCTTTAATCTCAGGGCTGCTAAACTCCGTAAAATTTTAATTTTCCTATACTACAACCATCAAGACTGCTACAAGTTGACAAAAAATTACCTTGTTTACATCTTTGTCACTGTGAATTTCTTTTTATTTTTTTTACTGTGATCTCTTTAATAACAGTATGTAAGAAAGTAAGTGATGAAAAGGTACCTGTACTGCTAATTGCTGGGAGTTCTTGTATGAATTAGTTCACTAGGTGGTGCTGTATATTTATCAATGCATTGTACACTTTATAAAGACATTAGTGTGACTGGCACTCCAATCATTGAATGGGCGTTAAAATGGAAGTGAGCCAGTGCAATCAATCTTCAAGGATAAACATAGTAAATCAATGGATTATTTGAAAAATAAAAAAAAGACAAAAAAAAAAAAAAA	Refseq >NM_001087787|Xenopus laevis cell division cycle 25 homolog C (cdc25c-a), mRNA GGAGCGGAAGATTCTAATTTTGTGTTGAAAGAAAAGAGAACACAGATGTCGTAGAGATAGATGGAAAGGGCTGTGGACACATCACATGCAGAGACTTGGCATGGAGAGTCGACTTGAATGATTAAGGAGCGTGTAACACCCCCGTTCCAGGCAAGTGGAGGTTCTGGTGTAGTCATGGCAGAGAGTCACATAATATCATCAGAAGCACCCCCAAAGTCCAACCCAGGTCTGAATATCCGTACTAACTGCCGAATGATTTTGAACCTGCTGCGCGAAAAAGATTGCTCTGTTACATTTTCACCGGAACAGCCTTTGACACCTGTGACTGACCTTGCTGTTGGATTTAGTAACCTAAGTACTTTCAGCGGTGAAACTCCCAAACGCTGCCTGGACTTGTCCAACCTTGGTGATGAGACTGCACCATTGCCAACAGAGTCTCCTGATAGAATGTCATCAGGTAAGCTGGAGTCTCCAAAGACACAATTTGTCCAGTTTGATGGCCTATTTACACCTGATCTCGCATGGAAAGCAAAGAAGTGTCCAAAGAGAAACATGAATTCTGTTCTGCCACACCTTCTTTGCAGCACTCCAAGTTTTAAAAAAGCCTCAGGAGGACAGAGAAGCTTGTCCAATAAAGAAAATGAGGGTGAGCTGTTTAAGAATCCAAACTGTAAACCTGTTGCTTTGCTGCTACCACAAGAAGTAGTTGATTCACAATTATCTCCAACACCTGAGAACAAGGTGGATATCTCCCTAGATGAGGATTGTGAAATGAATATCTTGGGATCCCCCATAAGTGCTGATCCCCCTTGTTTGGATGGAGCACATGATGACATCAAAATGCAAAATCTTGATGGATTTGCAGATTTTTTTTCTGTTGACGAAGAGGAGATGGAGAATCCTCCTGGAGCTGTCGGTAACTTGTCCTGTAGTATGGCAATTCTTCTGTCGGGGCCCCTTCTAAATCAAGATGTAGAAATCAGCAATGTAAACAATATATCTTTAAACAGAAGCCGCCTTTACCGCTCACCTTCTATGCCAGAGAAACTTGACAGGCCAATGCTTAAACGCCCAGTGAGGCCGCTAAACAGTGAAACACCCGTCAGAGTGAAAAGGAGACGTAGTACCAGCAGCCCCCTTCAACCTGAGGAAGAGAACTGCCAACCACAGAGGAGGGGTACTTCTCTTAAAAAGACACTTTCTCTTTGTGATGTGGATATCAGTTCAGTTTTGGATGAAGATTGTGGTCACAGACAACTAATTGGAGATTTTTCAAAGGTTTATGCTTTACCCACTGTTACTGGCCGACACCAGGACCTCCGATACATCACTGGAGAGACTCTGGCAGCCTTAATGCATGGAGACTTCAACAGTTTAGTGGAGAAATTCTTTATAATCGATTGCCGTTATCCTTACGAGTATGATGGAGGACACATCAAGAGTGCATTTAACCTTCACCGGCAAGATGAGGTAACGGACTACTTTCTGCAACAACCACTGACCCCGTTGATGGCACAGAAGAGATTAATTATAATCTTTCATTGCGAGTTCTCTTCTGAAAGAGGCCCAAAAATGTGTCGGTCTCTCAGGGAGGAAGACAGAGCCAGTAATGATTACCCAAGCCTCTATTACCCAGAGCTTTATCTCCTTAAAGGCGGTTACAAGGATTTTTTTCCTGAATACAAGGAGCTATGTGAACCGCAGAGTTACTGCCCAATGCACCACCAAGATTTCCGCGAGGACCTGCTGAAATTCCGAACAAAATGTAAGACTTCTGTTGGCGATCGAAAGAGGAGGGAACCGGAATTCCGTTTGACAGGGCAAAGGCTTGGGTGAAGGAGTTACAGAGACAGGCTAGCCCCAATATCGTTATCGCTTTGGCTGGAAATAAATCGGATTTGGCAGAAAAACGGATGGTGGAGTATGAGGAAGCTCAAACTTATGCAGAAGACACTGGACTCTTATTCATGGAAACGTCTGCCAAAACTGCCATGAATGTAAATGAGTTGTTTCTAGCAATAGCAAAGAAAATGCCGAAATCTGATGCCCAAAACCCCACGCACGGGGCCCACAAACCGAGGTGTAAATGTCCAGGGTTCAGAGCAGCAGCCAAGAAGTGGGTGTTGTGGGAACTGATCCCATTCAGTGCAAGACCCTTCAATATGCATCTTTTACACAAACAGTTGTGAACACTGGTCTGCCTGCTGCCTCCTGGTTTTCCACAGCAGGTGAAATTTGTCTTTATATTTTTTTCCAGGTTTTGTTCCTTTTTATATCGTACAGTATTAAGATGAGTAAAGCAGAGAAAAAAACCTAAACCCACTCAGTCTGCAAGCTCCAGAACTAACTTAGAGAATGGGCAGAATAACTGCGCTGCAGTTGAGACAACATGTAATATGCACTTATCCAAGCATGTCCAGTTGGCTGCTAATAACCCCCACAGCTAAATCTAATGTAATCTCTATGCTGCACATGTCCAAATGATCTTTCTGTTATGAGAACTCTTCTCTGGATTCCCACACAAAACAGCAGGTCCAAGTACAGCTGAATGGTACAGATGAGAATTCAGCAGCTCATCTGGTTTAATCTGGCACAAGTGGAGTGGTGCTTGTGTGGCATATTTGCATATTAAACCTCTACAACTACTGTCCAGTTGACCTTCAAGGATCAGACAGGAAGATGATAGTCCTCTCCAGCCTTAGTAAGGCCACATGCATCTCCCTTAACAAAGAACAAAGCCCTGTGAAATGATGGCACTTTACTTACCCTTTAATACATTTCTGTTTAACTGAAAACCCTGATGATCTAGTCACCTGCGTGTAAATTACCCCACTCACGTTGTAAATCTCAAAAAATAGAACATCTGAACATGACTTTTGTATTTGCACCTTCGGATAATGTTTTACTTGAAATGACTCCTAAATATTGATTTTTAATGTAAGATTAAAGCAAAGTGATGAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA		Refseq >NM_001088449|Xenopus laevis cell division cycle 25 homolog C (cdc25c-b), mRNA TTTTTTTTTTTTTTTACGTATTTGTAACTGGTATAGTAGCAGGGTTCCGAGTGGTGAAACAAAAGAGGGTACAGCTACTGTAGGGGTAAAAGGGAAGGGTTCTGCACACTCACACATCACAACTTGTTTCACACGCACAGAGAGAGTGCTGCATGGCGATGGAAAGTCGACTTGAATAATTAAGGAACCTGCAACCCCCGAATCAAATTTCCAGGTTCCAGGCAAATAGTGAAGTCATGGCAGAGAGTCACATAATGTCATCAGAAGCACCCCCAAAAACCAACACAGGCCTGAATTTCCGTACAAATTGCCGAATGGTATTAAACCTGCTTCGTGAAAAAGATTGTTCTGTTACATTTTCTCCGGAACAGCCTTTGACACCTGTGACTGACCTTGCTGTTGGATTTAGTAACCTAAGTACCTTCAGTGGTGAAACTCCCAAACGCTGCCTGGACTTGTCCAACCTTGGTGATGAGACTGCACCACTGCCAACAGAGTCTCCTGATAGAATATCATCAGGTAAGGTGGAGTCACCAAAGGCACAATTTGTCCAGTTTGATGGCCTATTTACTCCTGATCTCGGGTGGAAAGCAAAAAAGTGTCCGAGAGGAAACATGAATTCTGTTCTGCCACGCCTTCTTTGCAGCACTCCAAGTTTTAAAAAGACCTCAGGAGGACAGAGAAGTGTGTCTAATAAAGAAAATGAGGGTGAGCTGTTTAAGAGTCCAAACTGTAAACCTGTTGCTTTGCTGCTACCACAAGAAGTAGTTGATTCACAATTTTCTCCAACACCTGAGAACAAGGTGGATATCTCCCTAGATGAGGATTGTGAGATGAATATCTTGGGATCCCCCATAAGTGCTGATCCCCCTTGTTTGGATGGCGCACATGATGACATCAAAATGCAAAATCTTGATGGATTTGCAGATTTTTTTTCTGTTGATGAAGAGGAAATGGAGAATCCTCCTGGAGCTGTTGGTAACTTGTCCTCTAGCATGGCAATTCTTCTGTCGGGACCCCTTCTAAATCAAGACATAGAAGTCAGCAATGTAAACAATATATCTTTAAACAGAAGCCGCCTTTACCGCTCACCTTCTATGCCAGAGAAACTTGACAGGCCAATGCTTAAACGGCCAGTGAGGCCACTAGACAGTGAAACGCCGGTCAGAGTGAAAAGGAGACGTAGTACCAGCAGCTCCCTTCAACCACAGGAAGAGAACTTCCAACCACAGAGGAGGGGTACTTCTCTTAAAAAGACGCTTTCTCTTTGTGATGTGGATATCAGTACAGTTTTGGATGAAGATTGTGGTCACAGACAGCTAATTGGAGATTTTACAAAGGTTTATGCTTTACCCACTGTTACTGGCCGACATCAGGACCTCCGATACATCACTGGAGAGACTTTGGCAGCATTAATTCATGGAGACTTCAGCAGTTTAGTGGAGAAAATCTTTATAATCGATTGTCGTTATCCTTATGAATATGATGGAGGACACATAAAGGGTGCATTAAACCTCCACCGGCAAGAGGAGGTAACTGACTACTTCCTGAAACAACCACTGACCCCAACGATGGCACAGAAGCGGTTAATTATCATTTTTCATTGCGAGTTCTCATCTGAAAGAGGTCCAAAAATGTGTCGGTTCCTCAGGGAGGAAGACCGAGCCAGGAATGAGTACCCAAGCCTCTATTACCCAGAGCTTTATCTCCTGAAAGGTGGTTACAAGGATTTTTTTCCTGAATACAAGGAACTCTGTGAACCGCAGAGCTACTGCCCAATGCACCACCAAGACTTCCGGGAGGAGCTGCTGAAATTCCGGACAAAATGTAAAACTTCGGTTGGTGATCGAAAGAGGAGGGAACAGATTGCCCGCATAATGAAGCTTTAATCTTGGGGCTCATGCCGTTGATCCATTTTCTTTTTTTTTTTTTTTTTTTCAAACAAAGGATGTAAACATCTGCCAGAATTTTAATTTTCTTCTAATACTACAACCATGAAAACTGCTACTGATTGGCAAATAATTTACCTTGTTTACATCTTTGTCACTGTGAATTTTATTATTTTTACTGTGATCGCTCTAAACATAGTGTGTAAGAAAGCGAGGGATGAAAGGGTACCTGTACTGCTAAATGCTGGGAGTCCTTGTATGCATTAATCCACTAGGTGGTGCTGTTTATTTATAGATGCATTGTACATTTTATTATTGTGACTTACACTCTTATCATAGAAACATTTAATGCTAATTAAAATGGGAAGTGAGACAGTGCAATCAAACTTCAAGGAGGAACATAGTAAACCAATGGATTATTT
Protein		NCBI Protein >AAI59062|cdc25c protein [Xenopus (Silurana) tropicalis] MFQTSSGGSAEVMAENHIMSSEAPPKSNQGLHFRTNCRMILNLLREKDSSVTFSPEQPLTPVTDLAVGFSNLSTFTGETPKRCLDLSNLGDETGPLPTESPDRMSLGKVESPKTQFVQFEFTPDLGCKAKKCQRGNMNSVLPRLLCSTPSFKKTSGGQRSMSNKENESELFKNPNCKPAALVLPQEAVDSQFSPAPEDKVDISLDEDCEMNILGSPISAAAPCLEGPHDDIKMQNLDGFADFFSVDEEEIENPSGAVGNLSSSMAILLSGPLLNQEVEVSNVNNISLNRSRLYRSPSMPEKLDRPMLKRTVRPQDSETPVRIKRRRSTSSPLQPEEENCQPRRRGTSLKKTLSLCDVDISTVLDEDCGHRQLIGDFSKVYALPTVTGRHQDLRYITAETLAALIHGDFSSLVENVFIIDCRYPYEYDGGHIKGALNLHRQEEVTDYFLKQPLAPSVAQKRLIIVFHCEFSSERGPKMCRFLREEDRARNEYPGLYYPELYLLKGGYKDFFPEYKELCEPQGYCPMHHQDFREELLKFRTKCKTSVGDRKRREQIARLMKL	Refseq >NP_001081256|M-phase inducer phosphatase 3 [Xenopus laevis] MIKERVTPPFQASGGSGVVMAESHIISSEAPPKSNPGLNIRTNCRMILNLLREKDCSVTFSPEQPLTPVTDLAVGFSNLSTFSGETPKRCLDLSNLGDETAPLPTESPDRMSSGKLESPKTQFVQFDGLFTPDLAWKAKKCPKRNMNSVLPHLLCSTPSFKKASGGQRSLSNKENEGELFKNPNCKPVALLLPQEVVDSQLSPTPENKVDISLDEDCEMNILGSPISADPPCLDGAHDDIKMQNLDGFADFFSVDEEEMENPPGAVGNLSCSMAILLSGPLLNQDVEISNVNNISLNRSRLYRSPSMPEKLDRPMLKRPVRPLNSETPVRVKRRRSTSSPLQPEEENCQPQRRGTSLKKTLSLCDVDISSVLDEDCGHRQLIGDFSKVYALPTVTGRHQDLRYITGETLAALMHGDFNSLVEKFFIIDCRYPYEYDGGHIKSAFNLHRQDEVTDYFLQQPLTPLMAQKRLIIIFHCEFSSERGPKMCRSLREEDRASNDYPSLYYPELYLLKGGYKDFFPEYKELCEPQSYCPMHHQDFREDLLKFRTKCKTSVGDRKRREPEFRLTGQRLG UniProtKB		Refseq >NP_001081918|M-phase inducer phosphatase 1-B [Xenopus laevis] MAESHIMSSEAPPKTNTGLNFRTNCRMVLNLLREKDCSVTFSPEQPLTPVTDLAVGFSNLSTFSGETPKRCLDLSNLGDETAPLPTESPDRISSGKVESPKAQFVQFDGLFTPDLGWKAKKCPRGNMNSVLPRLLCSTPSFKKTSGGQRSVSNKENEGELFKSPNCKPVALLLPQEVVDSQFSPTPENKVDISLDEDCEMNILGSPISADPPCLDGAHDDIKMQNLDGFADFFSVDEEEMENPPGAVGNLSSSMAILLSGPLLNQDIEVSNVNNISLNRSRLYRSPSMPEKLDRPMLKRPVRPLDSETPVRVKRRRSTSSSLQPQEENFQPQRRGTSLKKTLSLCDVDISTVLDEDCGHRQLIGDFTKVYALPTVTGRHQDLRYITGETLAALIHGDFSSLVEKIFIIDCRYPYEYDGGHIKGALNLHRQEEVTDYFLKQPLTPTMAQKRLIIIFHCEFSSERGPKMCRFLREEDRARNEYPSLYYPELYLLKGGYKDFFPEYKELCEPQSYCPMHHQDFREELLKFRTKCKTSVGDRKRREQIARIMKL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.52496	Xl.85437 [+] Xl.78641		Xl.513
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CDC25C
mouse		MGI	Cdc25c	All(1) Targeted, knock Out(1)
zebrafish

Publications
First:		Identification of a protein kinase multigene family of Dictyostelium discoideum: molecular cloning and expression of a cDNA encoding a developmentally regulated protein kinase. [Proc Natl Acad Sci U S A 1991]
Most recent:		Histone deacetylase induces accelerated maturation in Xenopus laevis oocytes. [Dev Growth Differ 2013]
		View All Papers 3 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		prenylated protein tyrosine phosphatase activity protein tyrosine phosphatase activity
Biological:		M phase of mitotic cell cycle protein amino acid dephosphorylation
Cellular Component:		intracellular
EC:		protein-tyrosine-phosphatase
KOG:		[D] M-phase inducer phosphatase

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.24455.1.S1_at	Xl.573.1.S1_at		Xl.513.1.S1_at
Affymetrix 2.0			Xl2.573.2.S1_a_at		Xl2.513.1.S1_at

Symbol legend[+]

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