[provisional- machine annotated only] Gene Symbol: pld1 [Predicted: Source is Human Entrez Gene] Gene Name: phospholipase D1, phosphatidylcholine-specific [Predicted: Source is Human Entrez Gene] Synonyms: phospholipase D Add Xenopus synonyms Gene Function: Phospholipase D1 Interactants: pla2g1b(3) , cdkn1a(1) , mapk1(1) , p2rx2(1) , p2rx7(1) , plcb1(1) , View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002931551|PREDICTED: Xenopus (Silurana) tropicalis phospholipase D1, phosphatidylcholine-specific (pld1), mRNA TGTCAGTCTGTAGGTGCGGGGCTGCTTGCTGTGGTAATCTGTAAAGCTGCTGAGGGTTGCGTGTGAAAAACTTTATCCAGGAAGAAGAAATCTCATCACTGGCACAATGTGCTTTCTCTCGGCACAGGGGCCAAAGGCCCTTGTGTTGCCAGCCTGTTAGTGTGCATTATGTCTCTGAAACTAGAAAGATCTATAGATTCCTCTGCCCTGCATAAAATTGCAGCAGACATGAGCAATCTCATAGAAAGCCTTGATACAAGTGAGCTCCGGTTTGAGGGAGAAGAAGTGGATGCTGACATCACAAGTGACACCAAAGTTAGTGGTGCCTGCTTTCCATTTTCTGCCATCTATCACACAAAGGGATTCAAAGACGCTGACCTTCAAGCATTTTTAATTGGATGTCCTATAAAAGTTCGGGTTTTGGAAGTTGAACGTTTTGCATCATCTTCTTCCTCAAAGGCACCAGTTCTAAATATCTATACAATAGAACTGACTCACGGAGAATTTACATGGCAAGTAAAGAGAAAATACAAGCACTTTCAAGATCTCCACAGAGAGCTGCTTCGGTACAAAGCGTTTATCCGAATCCCTATACCCACCCGAAGCCACACAGTAAGAAGACAAACAGTTAAAAGAGGAGATGTAAGGTCAATGCCAAACCTTCCACGAAATGCTGAGATTGTCAGAGAAGAACAGTCTTCAAGCAGAAGGAAACAGTTGGAAGATTACCTATCGGCACTATTAAAAATGCCCATGTACAGAAATTACCATGCAACTAGAGAATTTATTGATGTAAGTCAACTGTCTTTCATTCATGATCTTGGACCAAAGGGCATTGAAGGAACGATAATGAAGAGATCTGGTGGACACAGAATACCTGGTTTAAACTGCTGTGGACAAGGAAGTGTTTGCTATAGATGGTCAAAAAGGTGGTTGGTTGTAAAAGATTCATTTCTCCTCTACATGAAGTTAGACACCGGGGCTATTTCTTTTGTTTTACTGGTTGATAAGGAATTTAGCATAAAGATTGGCAAGAAAGAGACTGAGACCAAATATGGTTTACGAATTGACAATCTTTCAAGGACCTTGATACTGAAATGTAACAGCTACAGGCATGCCCGATGGTGGGGTCAGGCCATTGAGGAATTTGTAAGAAAGAACGGAAAGAACTTCCTTACTGATCACCGATTTGGTTCCTATGCAGCTATTCAAAATAACACACTTTCAAAATGGTATGTCAATGCGAAATTTTATTTCAGTGATGTGGCCGATGCAATGGAATCAGCAAAAGAGGAAATTTTCATCACAGATTGGTGGTTGAGTCCAGAAATCTTCCTAAAGCGTCCTGTTGTGGAAGGAAACAGATGGAGACTGGATTGCATTCTTAAACGAAAAGCACAACAAGGTGTAAAAATATTTGTTATGCTGTACAAGGAAGTAGAACTTGCTCTGGGAATCAACAGCGAGTACAGCAAGAGGACACTGCTACGTATTCATCCAAATATCAAGGTTATGAGGCACCCAGATCACATGTCTTCCTCAGTGTACCTTTGGGCTCATCATGAAAAGATTGTTGTGATAGATCAGTCTGTAGCTTTTGTTGGAGGGATTGACCTAGCCTACGGAAGATGGGATGATGATGAACACAGACTAACTGATGTTGGCAGCGTTAAGCGAATTGTAACAACACAGTCAACAACTGCAATAAATAAGATCTCATCTGATTCCACTTCATCTTTAAATGGTGATAACAGACCAGAGAAGAAGAAAAGTTTTGAAGTCCCGGCCAAGAAAGATGAGGATGCAGTGGATTCTTCAAGAATCAGAGGACTGGGAAAATCTAGGAAATTTGCCAAATTCAGTCTTTACAAACAGCTCCACAAGCACAACCTTCAGCATGCAGACAGTGTGAGCAGCATAGACAGTGAATCGCATAGAGGATCAATTCGCAGTTTGCAGACAGGCGTGGGAGAACTCTTAGGTGAAACACGTTTTTGGCATGGAAAGGACTACTGCAACTTTGTTTTTAAGGACTGGGTACAGCTGGACAAACCATTTGCAGATTTCATTGATCGATACCAGACCCCTAGAATGCCATGGCATGATATTGCTTCTGTTGTACATGGAAAAGCAGCACGAGACGTTGCAAGGCATTTCATCCAGCGATGGAACTTTGCTAAAATCATGAAACCAAAATATCGTTCCCTTTCCTACCCATTCTTGCTTCCAAAATCTAACAAAACTGCCAAGGAGTTACCCTATCAAGTTCCAGGGTCTGTGCATGCACAAGTACAGGTGTTGCGCTCTGCAGCGGATTGGTCGGCTGGTATTAAGTACCATGAAGAATCTATTCACAATGCATATGTACATGTGATAGAAAACAGCAAACACTACATTTACATTGAGAATCAATTTTTTATCAGTTGTGCTGACAACAAGCTTGTTTTTAACAAGATAGGGGATACCATTGCTCAGAGGATACTTAAAGCTCACAGGGAAAACAAAAGGTACCGCGTCTATGTTATTACTCCATTGCTTCCTGGATTTGAAGGAGATATTTCCACCGGAGGCGGTAGTGCCTTGCAGGCTGTTATGCACTTCAACTACAGGACCATTTGCAGAGGGGATAATTCCATCATTGGACAACTGAAAGCAGAAATTGGAAACCAGTGGATTAACTACATCTCGTTCTGCGGTTTGAGAACGCATGCGGAACTGGAAGGCAATCTGGTCACAGAGCTGATATATGTGCACAGCAAATTGCTCATTGCTGACGACAATACTGTCATAATTGGTTCTGCTAATATTAACGATCGCAGCATGATGGGAAAGCGTGACAGCGAGATGGCTGTTGTTTTTCAAGACACAGAGACGGTTCCATCGGTCATGGATGGCGAGACATATGAAGCTGGAAAATTCGCCCTGTCACTTAGGATGCATTGTTTCAGGCTGCTTCTTGGCTGCTTTAATGATCCTTCTGTCAACATCCAAGATCCTGTAAGTGACAAATTCTTCAAAGAAGTGTGGGTTGCAACTGCAGCAAGAAATACAACAATTTTTGACAAGGTCTTTAGATGCCTTCCCAGTGATGAAGTCCATAATTTTTTTCACCTTCCTGAGTACCTTGCTAAGCCAGGACTCGCCACGCAAGATCGTGTGAAAGCACAAGAGGAATTACAGAGGATCAAAGGTTTTGTGGTGCAGTTTCCCTTTTTCTTCCTGGCTGCAGAAAACCTCTTGCCTTCAGTTGGCACAAAAGAAGCCATGGTGCCCATGGAAACATGGACATGATCAAAATGTTATTGGGGGGGGTGTTATGTTTATGGTATAGCTGCCTGAAAGGAATGGAGTTTGCGAGAGACAACATGTTTAATGCAGCAGAACTGGTACCGACGGGTGGGTACTTGGAGTCCACACACTGTTTCACCATTGCATTTGTTCAAGCACCAAAGGGTTTAATCACAATCAAAGCAATTACCACTAAATGAAACACGGCTACTGTAAATTTTTACAGTACACACAAATCTCTTATTTCTGGGCCCAGGAAATGGTACTGCTAATGTTTTAAATATTACAAGTAAATTTTTTTTTTTTCATATTTTAAAAATGAGAGGTGCCTGTAGTTACATGTGCATGGTGACTGGGCAAAGTTTTACAGAGCTTAATTACCACTAACTGGATACCCAAGGCTATACACACATTTCTTTCCTATAGAATCGATTTGCTCTAATTAAATACACAAAGTATTGCTCTACTAGAAGCCTGCAGGGGGAGCTGTCGCTCAGCATCAGAAAACTGCAGTGTGTAGAAATGGGCTGTTGGATGAAATTCTTTTTCTTAAATTCCATACATGAAATTCCATGAAGGAGCATGTTATTGATACGCTATTGGCGTAATGCAACAGAACATGGGCAGTGTCTCTGAGCCATTCTTGCCAGGAAAGGGATTAACATTTCTGCTCCATTTTTAAGATTTTGTACGGTTCTCCAGCTCAGGCCTTAGTTACTGTGGGCTTTCACTACAAGCTGCATTTAGTGTTTCAGATAACATTTAATATATCTGGAGTGAACATATATCTGAAGAACAGTGCAATGTTCCAGTATGCAAACATTATTTGCCCTCTATTTAACATCACATTTTATAAAAGCCACTGAATATTTCACTTCTTCCCAAAGCTTCTGACCTTCTTTACAATTAGAGGGAAAAGCATGCTGTCTAGACCAATCCTGAATGAAGCCCAGTGGCACAAATATCCATTTAGAATTATTTTGGACAACTACCATCTGTAGTATCTTATTCTATCAGGTTTTTTCTGCACACACTTTGTATTCATGTTAGATATCATGAAAATAATACCATCATTGCCCTCTACGTCATTCAATGTTAGTACTGGCTGTTCATATGCCACATTCCATTCAGGCATGTAGAATTGTCTATATAGCACCATT	Refseq >NM_001136170|Xenopus laevis phospholipase D1, phosphatidylcholine-specific (pld1), mRNA GTGCTAATTGTGTAGGTGAGGGAATGTCTGCGCTCCCTCGCTCGGTTTGGTAATCTTAAAGGCGGCTGAAGGCTGTGCGTGAGGAAGTTTACACAGGAAGAAGATGTGCTTTCCCTTGGCACAGGGGCCACAGGCCCCTGTGTTTCCATCATGTCTCTGAAACTAGAAAGATCTATAGATTCATCTGCTTTGCAGAAAATTGCAGCAGACATGACAAATCTTATAGAAAGCCTTGATACAAGTGATCTCCGGTTTGATGGAGAAGAAGTGGATGCTGACTTCACAAGTGACACCAAAATTAGTGGTGCCTGCTATCCATTCTCTGCTATCTATAACACAAAAGGATTCAAAGAAGCTGACCTTCAAACGTTTTTGGTTGGATGTCCTATTAAAGTACGGGTTTTGGAAGTTGAACGTTTTGCATCATCATCTTCCTCAAAGGCGCCGGTTCTAAATATCTACACAATAGAATTGACTCACGGAGAATTTACATGGCAGGTAAAGAGAAAATACAAGCACTTTCAAGATCTCCACAGAGAGCTACTTCGGTACAAAGCTTTTATCCGTATCCCTATACCCATTAGAAGCCACACAGTAAGAAGACAGACTGTTAAAAGAGGAGATGTAAGGTCAATGCCAAACCTTCCACGGAATGCTGAGATTGTCAGAGAAGAACAGTCTTCAAGCAGAAGGAAACAGTTGGAAGATTACATATCTGCATTATTAAAAATGCCCATGTACAGAAATTACCATGCGACTAGAGAATTTATTGATGTAAGTCAGCTGTCTTTCATTCATGATCTTGGACCAAAGGGCATCGAAGGAACAATAATGAAGAGATCTGGTGGTCACAGAATACCTGGTTTAAATTGCTGTGGACAAGGAAGTGTTTGCTATCGATGGTCAAAAAGGTGGTTGGTTGTAAAAGATTCATTTCTTCTCTACATGAAGTTAGACACTGGGGCTATTTCTTTTGTTTTTCTGGTCGATAAGGAATTTACCATAAAGATTGGCAAGAAAGAGACAGAGACCAAATATGGTTTACGAATTGACAATCTTTCAAGGACCTTGATATTGAAATGTAACAGCTACAGGCATGCCCGATGGTGGGGTCAGGCAATTGAGGAATTTGTAAGAAAAAATGGCAAAAATTTCCTTACTGATCATCGATTTGGTTCATATGCAGCAATTCAAAATAACACACTTTCAAATTGGTATGTTAATGCAAAATGTTATTTCAATGATGTGGCTGATGCAATGGAAGCAGCAAAAGAAGAAATTTTCATCACAGATTGGTGGTTGAGTCCTGAAATCTTTCTCAAGCGTCCTGTTGTGGAAGGAAACAGATGGAGACTGGACTGCATTCTTAAACGAAAAGCTCAACAAGGTGTGAAAATTTTTGTTATGCTGTACAAGGAAGTAGAACTTGCTCTGGGCATCAACAGCGAATACAGCAAGAGGACCCTGCTGCGCATTCATCCAAATATTAAGGTTATGAGGCACCCAGATCACATGTCCTCCTCCGTGTACCTTTGGGCTCATCATGAAAAGATTGTTGTGATAGATCAGTCCGTAGCTTTTGTCGGAGGAATTGACCTGGCCTATGGAAGATGGGATGATGATGAACACAGACTAACTGATGTTGGCAGTGTAAAGCGGATTGTAACAACACAGTCAACAACTGCAATAAATAAGATCCCATCTGATCCTACTCTGTCATTGAATGGTGATAATAGGGCAGGGAAAAGAAGTTTTCAAGTTCCAGGCAAGAAAGATGAGGATGCAGTGGATTCATCGAGAATCAGAGGACTGGGGAAATCTAAGAAGTTTGCAAAATTTAGCCTTTACAAGCAGCTCCACAAACATAACCTCCAGCATGCAGACAGTGTGAGCAGCATAGACAGCGAATCTCATAGAGGATCAGTTCGCAGTTTGCAGACAGGCGTGGGAGAACTTTTGGGTGAAACCCGCTTTTGGCATGGAAAGGACTATTGCAACTTTGTTTTTAAGGACTGGGTACAGCTGGACAAACCATTTGCAGATTTCATTGATCGATACCAGACTCCTAGAATGCCATGGCACGATATTGCTTCTGTTGTACATGGAAAAGCAGCACGAGACGTTGCAAGGCATTTCATCCAACGATGGAACTTTACTAAAATAATGAAACCAAAATATCGTTCTCTTTCCTACCCATTCTTGCTGCCAAAATCTCACAAAACTGCCAAGGAGCTACCGTATCAAGTTCCAGGGTCTGTACATGCACAAGTGCAGGTGTTGCGCTCTGCAGCAGATTGGTCGGCTGGTATTAAGTACCATGAAGAGTCTATCCACAACGCATATGTGCATGTGATAGAGAACAGTAAACACTACATTTACATTGAGAACCAATTTTTTATCAGCTGTGCTGACAACAAGCATGTTTTTAACAAGATCGGGGATAGCATTGCTCAGAGAATACTTAAAGCTCACAGGGAAAACAAAAGGTACAGAGTCTATGTTATAACTCCGTTGCTTCCTGGATTCGAAGGAGATATTTCCACCGGAGGGGGCAGTGCCTTGCAGGCTGTTATGCACTTCAACTACAGGACCATTTGCAGAGGAGAGCATTCCATCATTGGACAACTGAAAGCAGAAATTGGAAACCAGTGGATTAACTACATATCGTTCTGCGGTTTGAGAACCCACGCGGAACTGGAAGGGAATCTTGTAACCGAGCTGATATATGTGCACAGCAAACTGCTCATCGCTGACGATAATACAGTTATTATTGGTTCTGCTAATATAAATGATCGCAGCATGATGGGGAAGCGTGACAGTGAGATGGCTGTTGTGTTTCAAGACACAGAGACTGTTCCATCGGTCATGGATGGCGAGACTTATGAAGCTGGAAAATTTGCCCTGTCTCTTAGGCTGCATTGTTTCAGGCTGATTCTTGGCTGCCTTAATGATCCTTCTGCCAACATCCAAGATCCTGTAAGTGACAAATTTTTCAAAGAAGTGTGGGTTGCAACTGCGGCACGCAATACCACTATTTTTGATAAGGTCTTTAGATGCCTTCCCAGTGATGAAGTTCATTATTTTTTCCACCTTCCCGAGTACCTTTCCAAGCCAGGACTCGCAACGCAAGATCGCGTGAAAGCGCAGGAAGAATTACAGAGAATCAAAGGTTTCGTGGTGCAGTTCCCCTTTTTCTTCCTAGCCGAAGAAAACCTCTTGCCCTCGGTTGGCACAAAAGAAGCCATGGTTCCCATGGAAACATGGACCTGAACAAAATGTTTTGCCTGGGGCACAGCACATGAAAAATCTTGCACACGTTAAATGGCACAACCAACTTCCAAAAAGGAATGGAGAGGACATGTTGTGCATCAGAACTGGTACCACTGGGGAGGGGGGGTACTCGTTTGGTTCCACACACTCTTTCACCCGTTACATTTGTTCAAGCAGCGCAGGAGTTAATCACAGTCAATTATTTAATACCACTAAATGAAACACGGCTCCTGTATATATTTAACAGCACACACAGCCACTACATCTCTTTTTTTCTGGGCCCAGGGAATGGTATATTCAAGGTTTTAAGGCTGGAAAAGAAGAGTAAATCTTATAAGTGATTATCTGTTTTTTTAATATTTCAATTAGATGTGTTTATTGTTATTTATACCTGTATGCTGGCTAGACAGTTATATGTGGCTTAATTCTCACTTATCCATGGTCTACACACATTTAGATAGGACTGGTAAATAAACCATACAGCTGAGGGTGGTGTGTGTGTAAGTCATGTGCCTAATAGAACTGCATTCTATGTCAGACATACAGTATTTCTATTTGGGGGCATTAATCAATTCTATGGAGACTACCAGTCACATAAACCAAAGTTCTTTAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002931597|PREDICTED: phospholipase D1 [Xenopus (Silurana) tropicalis] MSLKLERSIDSSALHKIAADMSNLIESLDTSELRFEGEEVDADITSDTKVSGACFPFSAIYHTKGFKDADLQAFLIGCPIKVRVLEVERFASSSSSKAPVLNIYTIELTHGEFTWQVKRKYKHFQDLHRELLRYKAFIRIPIPTRSHTVRRQTVKRGDVRSMPNLPRNAEIVREEQSSSRRKQLEDYLSALLKMPMYRNYHATREFIDVSQLSFIHDLGPKGIEGTIMKRSGGHRIPGLNCCGQGSVCYRWSKRWLVVKDSFLLYMKLDTGAISFVLLVDKEFSIKIGKKETETKYGLRIDNLSRTLILKCNSYRHARWWGQAIEEFVRKNGKNFLTDHRFGSYAAIQNNTLSKWYVNAKFYFSDVADAMESAKEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVKIFVMLYKEVELALGINSEYSKRTLLRIHPNIKVMRHPDHMSSSVYLWAHHEKIVVIDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRIVTTQSTTAINKISSDSTSSLNGDNRPEKKKSFEVPAKKDEDAVDSSRIRGLGKSRKFAKFSLYKQLHKHNLQHADSVSSIDSESHRGSIRSLQTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYQTPRMPWHDIASVVHGKAARDVARHFIQRWNFAKIMKPKYRSLSYPFLLPKSNKTAKELPYQVPGSVHAQVQVLRSAADWSAGIKYHEESIHNAYVHVIENSKHYIYIENQFFISCADNKLVFNKIGDTIAQRILKAHRENKRYRVYVITPLLPGFEGDISTGGGSALQAVMHFNYRTICRGDNSIIGQLKAEIGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMMGKRDSEMAVVFQDTETVPSVMDGETYEAGKFALSLRMHCFRLLLGCFNDPSVNIQDPVSDKFFKEVWVATAARNTTIFDKVFRCLPSDEVHNFFHLPEYLAKPGLATQDRVKAQEELQRIKGFVVQFPFFFLAAENLLPSVGTKEAMVPMETWT	Refseq >NP_001129642|phospholipase D1 [Xenopus laevis] MSLKLERSIDSSALQKIAADMTNLIESLDTSDLRFDGEEVDADFTSDTKISGACYPFSAIYNTKGFKEADLQTFLVGCPIKVRVLEVERFASSSSSKAPVLNIYTIELTHGEFTWQVKRKYKHFQDLHRELLRYKAFIRIPIPIRSHTVRRQTVKRGDVRSMPNLPRNAEIVREEQSSSRRKQLEDYISALLKMPMYRNYHATREFIDVSQLSFIHDLGPKGIEGTIMKRSGGHRIPGLNCCGQGSVCYRWSKRWLVVKDSFLLYMKLDTGAISFVFLVDKEFTIKIGKKETETKYGLRIDNLSRTLILKCNSYRHARWWGQAIEEFVRKNGKNFLTDHRFGSYAAIQNNTLSNWYVNAKCYFNDVADAMEAAKEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVKIFVMLYKEVELALGINSEYSKRTLLRIHPNIKVMRHPDHMSSSVYLWAHHEKIVVIDQSVAFVGGIDLAYGRWDDDEHRLTDVGSVKRIVTTQSTTAINKIPSDPTLSLNGDNRAGKRSFQVPGKKDEDAVDSSRIRGLGKSKKFAKFSLYKQLHKHNLQHADSVSSIDSESHRGSVRSLQTGVGELLGETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYQTPRMPWHDIASVVHGKAARDVARHFIQRWNFTKIMKPKYRSLSYPFLLPKSHKTAKELPYQVPGSVHAQVQVLRSAADWSAGIKYHEESIHNAYVHVIENSKHYIYIENQFFISCADNKHVFNKIGDSIAQRILKAHRENKRYRVYVITPLLPGFEGDISTGGGSALQAVMHFNYRTICRGEHSIIGQLKAEIGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLLIADDNTVIIGSANINDRSMMGKRDSEMAVVFQDTETVPSVMDGETYEAGKFALSLRLHCFRLILGCLNDPSANIQDPVSDKFFKEVWVATAARNTTIFDKVFRCLPSDEVHYFFHLPEYLSKPGLATQDRVKAQEELQRIKGFVVQFPFFFLAEENLLPSVGTKEAMVPMETWT

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.53925 [+] Str.37775	Xl.25177
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	PLD1
mouse		MGI	Pld1	All(4) Gene Trapped(1) Targeted, other(2)
zebrafish		ZFIN	pld1a

Publications
First:		Phospholipase-induced maturation of Xenopus laevis oocytes: mitogenic activity of generated metabolites. [J Cell Biochem 1993]
Most recent:		Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis. [J Lipid Res 2008]
		View All Papers

Functional Ontologies
GO: Molecular:		catalytic activity phospholipase D activity
Biological:		intracellular signaling cascade metabolic process
Cellular Component:
EC:		phospholipase D
KOG:		[I] Phospholipase D1

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.45361.1.A1_at [+] Str.37775.1.A1_at
Affymetrix 2.0			Xl2.25177.1.S1_at

Symbol legend[+]

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