[provisional- machine annotated only] Gene Symbol: ahcy [Predicted: Source is Human Entrez Gene] Gene Name: adenosylhomocysteinase [Predicted: Source is Human Entrez Gene] Synonyms: sahh, adenosylhomocysteinase Add Xenopus synonyms Gene Function: S-adenosylhomocysteine hydrolase Interactants: Ahcy Ab1(1) , eef2.1(1) , eef2.2(1) , View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001044429|Xenopus (Silurana) tropicalis S-adenosylhomocysteine hydrolase (LOC733486), mRNA TGAGATCTCCCTCCTCTTCACCATGTCTGACAAACTGTCCTACAAAGTCGCTGACATCAGCCTGGCCGAATGGGGCAGAAAGGCCATCGAAATTGCTGAGAATGAAATGCCCGGACTGATGAAGATGAGGGAGATGTACTCGGAATCCAAGCCCTTGAAAGGAGCCAGGATTGCGGGGTGCCTGCATATGACCCTCCAGACTGCTGTCCTTATCGAGACCCTGACTGCACTAGGAGCTGAGGTCCAATGGTCCAGCTGCAACATCTTCTCTACACAGGATCATGCTGCTGCAGCCATTGCCAAGACTGGAGTCCCCGTATACGCCTGGAAGGGTGAGACGGACGAGGAGTACATTTGGTGCATCGATCAGACCCTGTACTTCAAAGATGGCAAACCCCTCAACATGATCCTGGATGATGGTGGAGACCTGACCAATCTGGTTCACACCAAGTATCCCCAGCTACTGAAAGGCATTAAAGGAATCTCTGAAGAGACCACCACTGGCGTGCACAACCTCTACAAAATGAAGGCTAGCGGGACGCTGCAGGTTCCAGCCATTAATGTGAACGACTCTGTTACCAAGAGTAAGTTTGATAACCTGTACGGATGCAGAGAGTCGCTAATTGATGGCATTAAGCGGGCCACTGACGTTATGATCGCTGGCAAGGTAGCCGTTGTAGCCGGATATGGTGATGTCGGTAAGGGATGCGCACAAGCACTGAGAGCCTTCGGAGCCCGTGTCATCATCACTGAAATTGATCCAATCAATGCACTTCAGGCTGCTATGGAAGGATATGAAGTGACTACAATGGAAGAAGCCAGCAAAGAAGGAAATATCTTTGTGACCACTACTGGATGTACAGATATCGTAGAGGGCAGCCATTTTGAAAACATGAAAGATGATTCCATCGTCTGCAACATTGGCCATTTTGATTGTGAACTGGACGTGAAGTGGCTGAACGACAACGCTGTGAAGAAAGTCAATATCAAACCCCAGGTGGATCGCTATCTGCTGAAGAATGGCCGCCACATCATTCTGCTCGCTGAGGGCCGCCTGGTGAATTTGGGGTGCGCCATGGGGCACCCCAGCTTTGTCATGAGCAATTCATTTACAAATCAGGTGATGGCTCAGATTGAGCTGTGGACCAATAACGACAAGTATCCTGTCGGCGTATATTTCCTGCCAAAGAAGTTGGATGAGGCCGTAGCAGCTGCCCACCTCGACAAACTGGGAGTCAAGCTCACCAAGCTGACCGACAAACAAGCCAAGTATCTTGGGTTGGAGAAAGAAGGGCCTTTCAAACCCGATCACTACCGATACTAAGGATCCACAGACCCACAACCCCGGAACATATGAGTATTCTGCATCCAAAGCAACTATTACCCGGAGCCGACGGCCTCTCCTCCTAAAGCCTGGAATTTACTGGCACCCAAAAGTCAAGCTGAGCTGCTAAATCTGGTAGATTTGGATCTGTATATGGGTTTTTTTTCCACACCTTAATGAAAAAAATGTGCCTCCTCGTGTAACTAGACTGTTCCTCACTACTACACCCTCTCTGCAAAGCCAGTGAGTGATCGGTGCAAGTAGAGGTCAGGGCGCTGATGGGAGTTGTAGTTCAGTTTTAGAAAAACGGTTTCGGGAGCGCCAAACTACGATACCCGTCATCCTCAGGTGCCACTCAACAAGATCTCAATGGAAGATTGATCTGCAACATGCGGGTATCTAGAGGTTCTTTGCATACCCCCAGCCAATCTGTTATTGTTGGCTTTCCAGCTTTTTCTCTACTTTTTTTGTTGACTTTATCTATTGTTTTTTTCGGTCAAAAGGCTTTATTTTACCAAATTTTCTCCTTATTGTATCAAGCAACTCCCAGTATTGCCTCTTGCCTACCTCGGCCTGCTATTGTATTTCCCATTGGCCTTTCCTGTGACGCTTCCATTTTTTCCAGCAAGAGCCATTTTTTTCCAGTGGAAATTTGCCCTTCAGCAACCTCTACCTTGTATTTAGATTCATCCTTTTCAATGTTTGAAGTTAAAAGTTTGTACCCAGTTTTGAGACGGAGGTATACAGCAGTCTTTGGTAACAACAATAAAAAAAAAAAAAAAAAAA	Refseq >NM_001095558|Xenopus laevis adenosylhomocysteinase (ahcy-a), mRNA CAACGTGAGATCTCCCTCCTCTTCACCATGTCTGACAAACTGTCCTACAAAGTCGCTGACATCAGCCTGGCCGACTGGGGCAGAAAGGCCATAGAGATTGCTGAGAATGAAATGCCTGGACTGATGAAGATGAGGGAGATGCACTCTGAATCCAAGCCTTTGAAAGGAGCCAGGATTGCGGGGTGCCTGCATATGACCCTTCAGACTGCTGTCCTTATTGAGACCCTGACTGCACTAGGAGCTGAGGTGCAATGGTCCAGTTGCAACATCTTCTCTACACAGGATCACGCTGCTGCAGCCATTGCTAAAACTGGAGTCCCAGTGTACGCCTGGAAGGGTGAGACCGATGAAGAGTACATTTGGTGCATTGAGCAGACCATTTACTTTAAAGATGGCAAACCCCTCAACATGATCCTGGATGACGGTGGAGACCTGACCAATCTGGTTCACTCTAAGTATCCCCAGCTACTGAAAGGCATTAAAGGAATCTCTGAAGAGACCACCACTGGCGTTCACAACCTCTACAAAATGAAGTCCAGTGGAACACTGCAGGTGCCAGCCATTAATGTGAATGACTCTGTTACCAAGAGCAAGTTTGATAACCTGTATGGATGCAGAGAATCGCTCATTGATGGTATTAAGCGAGCCACCGATGTAATGATTGCTGGCAAGGTAGCTGTTGTAGCTGGATATGGTGATGTTGGTAAAGGATGTGCACAAGCGCTAAGAGCCTTTGGAGCCCGTGTCATCATCACTGAAATTGATCCAATCAATGCACTTCAGGCTGCTATGGAAGGATATGAAGTGACTACAATGGATGAAGCCAGCAAAGAAGGAAACATCTTTGTGACCACTACTGGATGTGCAGATATTGTAGAGGGCAGACATTTTGAAAACATGAAAGATGATTCCATTGTCTGCAACATTGGGCATTTTGATATAGAACTGGATGTGAAATGGCTGAACGAAAATGCTGTCAAAAAAGTCAACATCAAACCACAGGTGGATCGATATCTGCTGAAGAACGGGCGGCACATCATTCTGCTTGCCGAGGGCCGTCTGGTGAATTTGGGGTGCGCCATGGGACACCCCAGCTTTGTCATGAGCAATTCTTTCACAAATCAGGTGATGGCTCAGATTGAGCTGTGGACCAACACTGACAAGTATCCTGTCGGCGTATATTTCCTGCCAAAGAAGTTGGACGAGGCTGTAGCTGCTGCTCACCTTGACAAGCTGGGAGTCAAGCTCACCAAGCTGACAGACAAACAAGCCAAGTATCTTGGGCTGGACAAGGAAGGTCCTTTTAAACCTGATCACTACAGATACTAAGGATCCACCAACCCAAAACCTGGAACATAAAACAAGAGAATTCTGCATCCAAAGCAACCATTTCCCAGAGAGTATGGTCTCTCCTCCTGAAGCCTGGAATTTCATGGCAAATTCAAGTCTTATTGAGTTGCTAAATCTGGTATATTTGGATCTGTATATGGGGTTTTCTCACCATAATGGAAAAAATGTGCCTCTTTCTTCTGTAACTAGACTTTTCCTCACTACTACACCCTGTGAAGCCAATGAGTAATATGTGCAAGCAAAGGTCATGGCGTTGGGGTAGTTACAGTCCATCAGCTTTATTAGAACGGTTTTCCTAAGTTGGAAGCTCCAAACTGATACCTATCATCCTAAAGTGTCACTCAACAAGATCAGTATGGATTGGAAGATTGATTTGCAATGTGCGGGTATCTACAGGTCTTTGCACAACTCCAGCCAAATTGTTCATGTTTATTGGCTCTCCAGCTTTTTGTTGATTATATATTGGTTTTTTTTTCCCCCAAAGTGGATCCCTCAAAAGGCTTTGTTTTACCAATCTTCCTCCATGCTTTAACAAACATCTCCTAGTATTTGGTCTATCCTACCTCGGCCTGCTTGTCTTAAGAGCTTTTGTATTTCCTGATGTCTCTTTCCATTAGCCATTCCTGTAGCACTCTGATTATTGCAACAAGAACCTTAAACTTTTTTTTTTTTCATTTTTCCAGTGGAAATGTGAACTTCAGCAACTCTACCTTTATATTTAGGTCCAATCTTTTCCAACGTTGAACTTAAATGTTTGTCTCCAGTTTTCAGTGAATCAGCAATCTTCGGTAACCACAATAAAAAAAATAAATAAAAAAAATTAAAAATTAAAAAAAAAAAAAAA		Refseq >NM_001095571|Xenopus laevis adenosylhomocysteinase (ahcy-b), mRNA AGCAGCCCGCCCACTCTTCTTCTCCTGGCTCTTACCGTGAGATCTCCCTCCTCTTCACCATGTCTGACAAACTGTCCTACAAAGTCGCTGACATCAGCCTGGCCGACTGGGGCAGGAAGGCCATAGAAATTGCTGAGAATGAAATGCCTGGACTGATGAAGATGAGGGAGATGTACTCGGAATCCAAGCCTTTGAAAGGAGCCAGGATTGCGGGGTGTCTGCATATGACCCTCCAGACTGCTGTTCTTATCGAGACCCTGACTGCAATAGGAGCTGAGGTGCAATGGTCCAGCTGCAACATCTTCTCTACACAGGATCATGCTGCTGCAGCCATTGCTAAGACTGGAGTCCCAGTGTACGCCTGGAAGGGTGAGACAGATGAGGAGTACATTTGGTGTATCGAGCAGACCATATACTTCAAAGATGGCAAACCTCTCAACATGATCCTGGATGATGGTGGAGACCTGACCAATCTGGTTCACACCAAGTATCCCCAACTACTAAAAGGCATTAAAGGAATCTCTGAAGAGACCACCACTGGTGTTCACAACCTCTACAAAATGAAGTCCAGCGGGACGCTGCAGGTGCCAGCCATTAATGTGAACGACTCTGTTACCAAGAGCAAGTTTGATAACCTGTATGGATGCAGAGAATCTCTAATTGATGGCATTAAGCGAGCCACTGATGTTATGATCGCTGGCAAGGTAGCCGTTGTAGCCGGATATGGTGATGTTGGTAAAGGATGTGCCCAAGCGCTTAGAGCCTTTGGAGCCCGTGTCCTCATCACTGAAATTGATCCAATCAACGCACTTCAGGCTGCTATGGAAGGATATGAAGTGACTACAATGGATGAAGCCAGCAAAGAAGGAAACATCTTTGTGACCACTACTGGATGTGCTGATATTGTAGAGGGCAGACATTTTGAAAACATGAAAGATGATTCTATTGTCTGCAACATTGGCCATTTTGATGTAGAACTGGATGTAAAATGGCTGAATGATAACGCTGCCAAGAAAATCAACATCAAACCACAGGTGGATCGCTATCTGCTGAAGAACGGTCGGCACATCATTCTGCTTGCTGAGGGCCGTCTGGTGAATTTGGGGTGCGCCATGGGACACCCCAGCTTTGTCATGAGCAATTCATTTACAAATCAGGTTATGGCTCAGATTGAGCTGTGGACCAACACTGACAAATATCCTGTTGGCGTATATTTCCTGCCAAAGAAGTTGGATGAGGCTGTAGCAGCTGCTCACCTTGACAAACTGGGAGTCAAGCTCACCAAGCTGACCGACAAACAAGCCAAGTATCTTGGGCTGGATAAGGAAGGGCCTTTCAAACCTGATCACTACCGATACTAAGAATCCACGAACCCAAAACCTGGAACATAAAACGAGTATTCTGCATCCAAAGCAACCATTTCCCAGAGTGGATGGCCTCTCCTCCTAGTGTCTGGATCTGCTATATTTTGGATCTGTATATGGTTTTTCTTACCATAATGAAAACTGTGCCTCTTTCTTGTGTAACTTGACTGTTTTTTCCCTCACTACTACATCCTGTCTCTGAAGCCAGTGAGTGATGTGCAAGTAGTGGTTTTGGCGTTGGCATAGCTGTAGTTCATAAACTACGGTTTCCTTAAGAGGGGAGTGTGAAACTCAGATACCCATCATCCTCAAGTGTCGGTCAGGAAGATCTGTATGGAATAGAAGATTGATTTGCAACATGCAGCTGTCTTTGCACAGCCCCAGCCAAACTGTTCCTTTTATTGGCTTTTCAGTTGTTTTTTTTCCCAAAGTGGATCAGTCAAAAGCTTTTATTTTACCAATCTTACCATCTCCAAGTATTGGCTCTTTCCTACCTCAGCCTACTTGTCTTAATAGCTTTTGTATTTGATATCTCATGCCATTAGCCTTTCATGTGGCACCTATCTTTTTCATTTCTCCAGTGGTAACGTAAACGTTAGCAACTCTACCATGTGTACAATCATTTCCAATGTTAAACTTAAATGTTTGTCTCCAGTTTTCAGTCAGAGGTATACAGCAGTCTTCGGTAACCACAATAAAAGTATTACAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001037894|adenosylhomocysteinase [Xenopus (Silurana) tropicalis] MSDKLSYKVADISLAEWGRKAIEIAENEMPGLMKMREMYSESKPLKGARIAGCLHMTLQTAVLIETLTALGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGETDEEYIWCIDQTLYFKDGKPLNMILDDGGDLTNLVHTKYPQLLKGIKGISEETTTGVHNLYKMKASGTLQVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRAFGARVIITEIDPINALQAAMEGYEVTTMEEASKEGNIFVTTTGCTDIVEGSHFENMKDDSIVCNIGHFDCELDVKWLNDNAVKKVNIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNNDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLGLEKEGPFKPDHYRY	Refseq >NP_001089027|adenosylhomocysteinase A [Xenopus laevis] MSDKLSYKVADISLADWGRKAIEIAENEMPGLMKMREMHSESKPLKGARIAGCLHMTLQTAVLIETLTALGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGETDEEYIWCIEQTIYFKDGKPLNMILDDGGDLTNLVHSKYPQLLKGIKGISEETTTGVHNLYKMKSSGTLQVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRAFGARVIITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENMKDDSIVCNIGHFDIELDVKWLNENAVKKVNIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLGLDKEGPFKPDHYRY UniProtKB		Refseq >NP_001089040|adenosylhomocysteinase B [Xenopus laevis] MSDKLSYKVADISLADWGRKAIEIAENEMPGLMKMREMYSESKPLKGARIAGCLHMTLQTAVLIETLTAIGAEVQWSSCNIFSTQDHAAAAIAKTGVPVYAWKGETDEEYIWCIEQTIYFKDGKPLNMILDDGGDLTNLVHTKYPQLLKGIKGISEETTTGVHNLYKMKSSGTLQVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRAFGARVLITEIDPINALQAAMEGYEVTTMDEASKEGNIFVTTTGCADIVEGRHFENMKDDSIVCNIGHFDVELDVKWLNDNAAKKINIKPQVDRYLLKNGRHIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTNTDKYPVGVYFLPKKLDEAVAAAHLDKLGVKLTKLTDKQAKYLGLDKEGPFKPDHYRY UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.51869	Xl.937		Xl.1111
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	AHCY
mouse		MGI	Ahcy	All(4) Gene Trapped(1) Targeted, other(2) Targeted, knock Out(1)
zebrafish		ZFIN	ahcy	2 Lines(s)

Publications
First:		Nuclear accumulation of S-adenosylhomocysteine hydrolase in transcriptionally active cells during development of Xenopus laevis. [Mol Biol Cell 1999]
Most recent:		Proteomic screen for potential regulators of M-phase entry and quality of meiotic resumption in Xenopus laevis oocytes. [J Proteomics 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		adenosylhomocysteinase activity
Biological:		one-carbon compound metabolic process
Cellular Component:
EC:		adenosylhomocysteinase
KOG:		[H] S-adenosylhomocysteine hydrolase

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.51869.1.S1_at	Xl.937.1.S1_at		Xl.1111.1.S1_at
Affymetrix 2.0			Xl2.937.1.S1_at		Xl2.1111.1.S1_at

Symbol legend[+]

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