cdc7 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (35)

Nucleotides (166)

Interactants (45)

XB-GENEPAGE-951313

[provisional- machine annotated only] Gene Symbol: cdc7 [Predicted: Source is Human Entrez Gene] Gene Name: cell division cycle 7 [Predicted: Source is Human Entrez Gene] Synonyms: xcdc7 Add Xenopus synonyms Gene Function: Casein kinase II, alpha subunit Interactants: cdk2(14) , dbf4(13) , dbf4b(13) , cdc45(11) , cdc6(11) , antxr1(8) , atr(8) View All

XB-GENE-951314

XB-GENE-951321

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016581\|Xenopus (Silurana) tropicalis cell division cycle 7 homolog (cdc7), mRNA ACGAAATGTTAGCCCCGCCTCCCCCGCCGGGCGCGATCTTTCTGTGCAGCTGTGTGTTGTTATTCCGGTGATTTTTGGCGCCATTCGATTCACATTGCTTGTAGGGGGTGAGAATGAGTTCGGGGGACACTGCAGGAGTGGCAAAGGAAATTGAAAAGCTGTATGCGGCTGTACCTCAACTTTGCAATATTTTCTACATTAAAAGCAAAATTGGGGAAGGTACATTTAGTTCTGTGTATTTGGCCATTGGAAGGCTGAGGTCTGGAGAAGATGTAACGTTTGCTTTAAAACATTTAATCCCCACAAGTCATCCAACTCGAATTGCAGCAGAACTCCAGTGCCTTTCAGTAGCTGGCGGTGAAGACAATGTAATGGGAGTTAAGTACTGCTTTAGAAATAAAGATCACGTGGTTATTGTAATGCCTTATTTAGAACATGAATGTTTTGCGGATATTTTGCATTCACTTAGCTTGGAGGAAACTAAAGAATATATGTTTAATCTCTTGAAAGCTCTTAGACGTATACACAGTTTTGGTATAGTCCATCGAGATGTTAAACCAAGCAATTTTCTGTACAACAGATCTCTTAAAAAGTTTGCATTAGTAGACTTTGGCTTGGCTCAAGGAACACCAGACACAAAAATTGATCTTCTGAAAGTTCTGCAGCCCAAAAAACAGGAAGGGCTGTTTGGCAGCTCTGCTCAGCGGTCTGTATTTGGAGAGAGGAATTTTAATGTGCACAGTGCTGTCACCACTGACAACACCACTTTAAAAGCAGTAAAACCATCCAAAATGCTAGATGTAACAACAAGAAAGCTGGCAACAAGAAAGACTGTTTCTGCAAAAAGCACAAGTAGTAGTGTCAATAAGAAAGCTTCCAGTATATGCCAAACAAGCTTGGCCTGCGACTGTTATGCAAAAGATCAAGTGTGTAATATTTGCCTTGCAAGGACACGACAAGTTGCTCCAAGAGCTGGTACTCCTGGTTTTCGTGCTCCCGAGGTCCTCACAAAATGTCCCCATCAAACTACTGCAATTGACATGTGGTCTGCAGGCATCATCTTTCTTTCTTTACTAAGCGGAAGATATCATTTTTTTAATGCTGCGGATGATATGAATGCTTTGGCCCAGATTATGACGATTCGTGGATCTAAGGAGACAATACAAGCTTCTAAATGTTTTGGTAAAAATTTGCTTTGTAGTAAAGAACTTCCTTCAAAGGACTTAAAAACTCTGTGTGAAGGGTTGAGAAGTGCAGTCCTTCTTCCAAATGGTGATCAACATGACATACAAAAACAAAGGGCTGCTTTACAAATGCAGATAATGGAAAATCAAGATGGATGGTTTTCACCAGAATCGTCTAATATAACTCATGCTTCTTCTATGGTTGCTAGTTGTGTGTCTGCACCTGATAATATGGATATTGAACAATCTAATCTTAATGGGTGGGATAGAGTCCCAAATGAGGCTTATCATCTATTAGACAGACTTCTTGATATGAATCCAGCAACAAGAATTACTGCAGAAGAAGCTTTAATACACCCACTTTTTAAAAACATGAGGTAATGTGTTGTCACCTTCTGCTTGTACTGCCAAGAATAAGGAAAATATTTCAAATTTTTGTATTATAGGTTTATTTTTAAATTATTTAAATAAATTCTCATTTTTGTAAAAAAAAAAAAAAAAAA	Refseq >NM_001088409\|Xenopus laevis cell division cycle 7 homolog (cdc7), mRNA CACGCGTCCGGCAGCTGTGGGTTGTTACGCCTGTGAATTTTGGCGCCATTCGTTTTACGTACTTGTCGGGGCGAGAATGAGTTCGGGCGATAATTCAGGAGTTGCAAAGGAAATTGAAAAGCTGTATGCAGCTGTACCTCAACTTCACAATATTTTCTACATTAAAAGCAAAATTGGGGAAGGTACATTTAGTTCTGTGTATTTTGCAATTGGAAGGCTGAGGTCTGGAGAAGATGCAAAGTTTGCTTTAAAACATTTAATCCCCACAAGTCACCCAACTCGAATTGCAGCAGAACTCCAGTGCCTTTCAGTAGCTGGTGGCGAAGACAATGTAATGGGAGTAAAGTACTGCTTTAGAAACAAAGATCATGTGGTTATTGTTATGCCTTACTTGGAACATGAATGTTTTGCGGACATTTTGCATTCACTCAGCTTTGAGGAAACTAAAGAATATATGTTTAATCTCTTGAAAGCTCTCAGACATATACATAGTTTTGGAATAGTTCATCGAGATGTTAAACCAAGCAATTTTCTGTTCAACAGGTCTCTCAAAAAGTTTGCATTAGTAGACTTTGGATTGGCTCAAGGAACATCAGACACAAAAATTGATCTTTTGAAAGTTCTGCAGCCTAAAAAACAGGATGGACTGGTTGGCAGCTCTACTCAGCGGTCTGTATTTGGAGAGAGGAATTTTAATGTGCACAGTGCTGTCACCATTGACAATACGACTTTAAAAGCAGCTAAACCATCCAAAACGATAGATGTAACAACAAGAAAGCTGGCAACAAGAAAGACTGTTTCTACGAAAAGCACCAGTAGTGCTGTCCCCAAAAAAGCTGCCAGTACATGCCAGACAAGCTTGACCTGTGACTGTTACGCAAAAGATCAAGTGTGTAATATTTGCCTTGCAAGGACTCGGCAAGTTGCTCCAAGAGCTGGTACTCCTGGTTTTCGTGCTCCTGAGGTCCTCACAAAATGTCCCCATCAAACTACAGCAATTGACATGTGGTCTGCAGGCATCATCTTTCTTTCTTTACTGAGCGGAAGATATCATTTTTTTAATGCTGCTGATGATATGAATGCTTTGGCACAGATTATGACAATCCGTGGATCTAAGGAGACAATCCAAGCTTCTAAATGTTTTGGTAAAAGTGTGCTTTGTAGTAAAGAACTTCCTTCAAAGGACTTAAGAACTCTATGTGAAGGGTTGAGAAGTGCTATTGTTCTTCCAAATGGCAATCAACATGATATACAAAAACAAAGGGCTGCATTACAAATGCGAATAATGGAAAATCAGGATGGATGGTTTTTGCCAGAATCACCTGATATAACTCCTGATTCCCCTGCGGTTGTTCGCTCCAGTTGTGTATCAACACCTGATAATATGGAACAATCCAATCACAATGGGTGGGATAGAGTCCCAAATGAAGCTTATCATCTTTTAGATAGACTTCTTGATATGAATCCAGCAACAAGAATAACAGCAGAAGAAGCTTTAATACATCCTCTGTTTAAAAACATGCGGTAGTGTATGTGCTGTCACCTCTTCTGCTTGTAATTTTTTTTCATATTATAATTTTATTTTTAAATTATTTAAATAAATGTTTTTGTTTTTTTTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016581\|cell division cycle 7 [Xenopus (Silurana) tropicalis] MSSGDTAGVAKEIEKLYAAVPQLCNIFYIKSKIGEGTFSSVYLAIGRLRSGEDVTFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSLEETKEYMFNLLKALRRIHSFGIVHRDVKPSNFLYNRSLKKFALVDFGLAQGTPDTKIDLLKVLQPKKQEGLFGSSAQRSVFGERNFNVHSAVTTDNTTLKAVKPSKMLDVTTRKLATRKTVSAKSTSSSVNKKASSICQTSLACDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKNLLCSKELPSKDLKTLCEGLRSAVLLPNGDQHDIQKQRAALQMQIMENQDGWFSPESSNITHASSMVASCVSAPDNMDIEQSNLNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLFKNMR	Refseq >NP_001081878\|cell division cycle 7 homolog [Xenopus laevis] MSSGDNSGVAKEIEKLYAAVPQLHNIFYIKSKIGEGTFSSVYFAIGRLRSGEDAKFALKHLIPTSHPTRIAAELQCLSVAGGEDNVMGVKYCFRNKDHVVIVMPYLEHECFADILHSLSFEETKEYMFNLLKALRHIHSFGIVHRDVKPSNFLFNRSLKKFALVDFGLAQGTSDTKIDLLKVLQPKKQDGLVGSSTQRSVFGERNFNVHSAVTIDNTTLKAAKPSKTIDVTTRKLATRKTVSTKSTSSAVPKKAASTCQTSLTCDCYAKDQVCNICLARTRQVAPRAGTPGFRAPEVLTKCPHQTTAIDMWSAGIIFLSLLSGRYHFFNAADDMNALAQIMTIRGSKETIQASKCFGKSVLCSKELPSKDLRTLCEGLRSAIVLPNGNQHDIQKQRAALQMRIMENQDGWFLPESPDITPDSPAVVRSSCVSTPDNMEQSNHNGWDRVPNEAYHLLDRLLDMNPATRITAEEALIHPLFKNMR

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.6524	Xl.468
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CDC7
mouse		MGI	Cdc7	All(6) Targeted, knock Out(2) Targeted, other(4)
zebrafish		ZFIN	cdc7

Publications
First:		Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7. [EMBO J 1997]
Most recent:		Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication. [Biochim Biophys Acta 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		3-phosphoinositide-dependent protein kinase activity AMP-activated protein kinase activity ATP binding More[+] DNA-dependent protein kinase activity G-protein coupled receptor kinase activity IkappaB kinase activity JUN kinase activity JUN kinase kinase activity JUN kinase kinase kinase activity Janus kinase activity MAP kinase 1 activity MAP kinase 2 activity MAP kinase activity MAP kinase kinase activity MAP kinase kinase kinase activity MAP kinase kinase kinase kinase activity MAP/ERK kinase kinase activity MP kinase activity NF-kappaB-inducing kinase activity SAP kinase activity atypical protein kinase C activity cGMP-dependent protein kinase activity calcium-dependent protein kinase C activity calmodulin-dependent protein kinase activity casein kinase I activity casein kinase activity cobinamide kinase activity cyclic nucleotide-dependent protein kinase activity cyclin-dependent protein kinase activating kinase activity cyclin-dependent protein kinase activating kinase regulator activity cyclin-dependent protein kinase activity cyclin-dependent protein kinase regulator activity diacylglycerol-activated phospholipid-dependent protein kinase C activity elongation factor-2 kinase activity eukaryotic elongation factor-2 kinase activator activity eukaryotic elongation factor-2 kinase regulator activity eukaryotic translation initiation factor 2alpha kinase activity galactosyltransferase-associated kinase activity glycogen synthase kinase 3 activity multifunctional calcium- and calmodulin-regulated protein kinase activity non-membrane spanning protein tyrosine kinase activity phenol kinase activity phosphatidylinositol phosphate kinase activity phosphofructokinase activity phosphoinositide 3-kinase activity phosphorylase kinase activity phosphorylase kinase regulator activity phosphotransferase activity, alcohol group as acceptor protein kinase C activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity receptor signaling protein serine/threonine kinase activity receptor signaling protein tyrosine kinase activity ribosomal protein S6 kinase activity transmembrane receptor protein kinase activity transmembrane receptor protein serine/threonine kinase activity transmembrane receptor protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:
EC:		Phosphotransferases with an Alcohol Group as Acceptor
KOG:		[TDK] Casein kinase II, alpha subunit

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6524.1.S1_s_at [+] Str.46223.1.A1_at Str.47523.1.A1_at	Xl.468.1.S1_at
Affymetrix 2.0			Xl2.468.1.S1_at

Symbol legend[+]