The dr1 protein is a transcription corepressor that down-regulates transcription by binding to tata-box-binding protein, inhibiting the formation of the pre-initiation complex. it localizes to the nucl...[+]

The dr1 protein is a transcription corepressor that down-regulates transcription by binding to tata-box-binding protein, inhibiting the formation of the pre-initiation complex. it localizes to the nucleus. expression is detected in the brain, spinal cord, eye, otic vesicle, heart, and gut during development. this protein interacts with the wnt signaling pathway. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD