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Summary Expression Phenotypes Gene Literature (0) GO Terms (24) Nucleotides (65) Proteins (40) Interactants (2) Wiki
XB-GENEPAGE-5858610
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 nlrc4

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NLR family, CARD domain containing 4

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( Nomenclature history )

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apoptosis regulator

Protein Function :
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokin...[+]


InterPro :
NLRC4 HD, DEATH-like dom sf, NACHT NTPase, P-loop NTPase, [+]

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Diseases: 


Disease Ontology:
familial cold autoinflammatory syndrome [+]

MIM:
AUTOINFLAMMATION WITH INFANTILE ENTEROCOLITIS; AIFEC [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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