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Summary Expression Phenotypes Gene Literature (152) GO Terms (90) Nucleotides (388) Proteins (54) Interactants (832) Wiki
XB-GENEPAGE-941539
???displayGene.symbol???:
 plk1

???displayGene.name???: 
polo like kinase 1

???displayGene.synonyms???
LOC108701628 , plk , PLK-1 , Plx1 , polo-like kinase 1 [-] ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

Protein Function :
Plays multiple essential roles during mitosis. Phosphorylates the N-terminal domain of cdc25, which leads to cyclin b-cdc2 activation and mitotic entry. Also required for organization of bipolar spindl...[+]


InterPro :
Protein kinase ATP BS, POLO box 2, Ser/Thr kinase AS, Kinase-like dom sf, [+]

???displayGene.geneInteractants???
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Diseases: 


External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info