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Summary Expression Gene Literature (50) GO Terms (22) Nucleotides (172) Proteins (34) Interactants (99) Wiki
XB-GENEPAGE- 1000547

Gene Symbol: pola1

Gene Name: polymerase (DNA directed), alpha 1, catalytic subunit

Synonyms: pola , DNA polymerase alpha
Add Xenopus synonyms , Nomenclature history


Gene Function: DNA polymerase alpha, catalytic subunit

Protein Function:
Plays an essential role in the initiation of DNA replication. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, a regulatory subunit PO...[+]


Interactants: YYY

OMIM Disease Associations: N SYNDROME; NSX
 
Xenbase Gene ID XB-GENE-1000548 XB-GENE-17346291 XB-GENE-1000552
Gene Symbol pola1 pola1.L pola1.S
Chromosome Chr02 chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.46145 Xl.7596
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine pola1 pola1.L pola1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards POLA1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Pola1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN pola1 ZFIN Ensembl
chicken
GEISHA POLA1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Nuclear localization of DNA polymerase alpha in Xenopus laevis oocytes. [Biochem Biophys Res Commun 1976]
Most recent: A large scale screen for neural stem cell markers in Xenopus retina. [Dev Neurobiol 2012]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 22 terms
EC DNA-directed DNA polymerase
PANTHER pola1
KEGG Pathways K02320
KOG [L] DNA polymerase alpha, catalytic subunit
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Pola1 Ab1 , Pola1 Ab2 Pola1 Ab1 , Pola1 Ab2 Pola1 Ab1 , Pola1 Ab2
Affymetrix 1.0 Str.22359.1.S1_at [+] Xl.7596.1.S1_at
Affymetrix 2.0 Xl2.7596.3.S1_a_at [+]

Symbol legend[+]

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