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Summary Expression Gene Literature (20) GO Terms (20) Nucleotides (231) Proteins (38) Interactants (314) Wiki
XB-GENEPAGE- 1000631

Gene Symbol: dctn2

Gene Name: dynactin subunit 2

Synonyms: rbp50 , dctn50 , dynamitin , dctn2-a , dctn2-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Putative dynamitin

Protein Function:
Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. M...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-1000632 XB-GENE-1000638 XB-GENE-6256553
Gene Symbol dctn2 dctn2.L dctn2.S
Chromosome scaffold_2 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.13521 Xl.8187 Xl.8282
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 4 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dctn2 dctn2.L dctn2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tegg139n15      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DCTN2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Dctn2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN dctn2 ZFIN Ensembl
chicken
GEISHA DCTN2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Recombinant p50/dynamitin as a tool to examine the role of dynactin in intracellular processes. [Methods Cell Biol 1999]
Most recent: Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts. [Dev Cell 2015]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 11 terms 11 terms
EC
PANTHER dctn2
KEGG Pathways K10424 K10424 K10424
KOG [Z] Putative dynamitin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino dctn2 MO1 , dctn2 MO2 dctn2 MO1 , dctn2 MO2 dctn2 MO1 , dctn2 MO2
ORF dctn2 ORF2 dctn2 ORF1
Affymetrix 1.0 Str.13521.1.S1_at Xl.8187.1.A1_at Xl.8282.1.S1_at
Affymetrix 2.0 Xl2.8187.1.S1_at Xl2.8282.1.S1_at

Symbol legend[+]

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