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Summary Expression Gene Literature (8) GO Terms (26) Nucleotides (264) Proteins (43) Interactants (167) Wiki
XB-GENEPAGE-1000683
Gene Symbol:
pfkm

Gene Name:
phosphofructokinase, muscle

Synonyms:
phosphofructokinase , pfk ( Add synonyms , Nomenclature history )

Gene Function:
Pyrophosphate-dependent phosphofructo-1-kinase

Protein Function :
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
glycogen storage disease VII

OMIM:
GLYCOGEN STORAGE DISEASE VII; GSD7

External Links:
 
Xenbase Gene ID XB-GENE-1000684 XB-GENE-17335184 XB-GENE-1000687
Gene Symbol pfkm pfkm.L pfkm.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216266
108708618
446756
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pfkm pfkm.L pfkm.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PFKM OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pfkm MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pfkm Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pfkmb pfkma ZFIN Ensembl
chicken
GEISHA PFKM Ensembl
fruit fly
Publications
First Changes in activity of the regulatory glycolytic enzymes and of the pyruvate-dehydrogenase complex during the development of Xenopus laevis., Exp Cell Biol 1986  
Most Recent Copy number variation as a genetic basis for heterotaxy and heterotaxy-spectrum congenital heart defects., Philos Trans R Soc Lond B Biol Sci 2016  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 26 terms 0 term 5 terms
PANTHER pfkm
KEGG Pathways K00850
KOG [G] Pyrophosphate-dependent phosphofructo-1-kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pfkm
ORFs pfkm.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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