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Summary Expression Gene Literature (12) GO Terms (17) Nucleotides (181) Proteins (43) Interactants (71) Wiki
XB-GENEPAGE-1001394
Gene Symbol:
mib1

Gene Name:
MIB E3 ubiquitin protein ligase 1

Synonyms:
mindbomb , mind bomb , mib , dip-1 ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intrac...[+]


InterPro :
Ig-like fold , Ig V-set , Ig-like dom sf , Ig-like dom [+]

Interactants:
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Diseases: 


Disease Ontology:
left ventricular noncompaction

OMIM:
LEFT VENTRICULAR NONCOMPACTION 7; LVNC7

External Links:
 
Xenbase Gene ID XB-GENE-1001395 XB-GENE-1001398 XB-GENE-17337704
Gene Symbol mib1 mib1.L mib1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100170182
444232
108695264
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine mib1 mib1.L mib1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards MIB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mib1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mib1 Ensembl
zebrafish
ZFIN, AGR mib1 ZFIN Ensembl
chicken
GEISHA MIB1 Ensembl
fruit fly
FLYBASE mib1 Ensembl
Publications
First The patterning and functioning of protrusive activity during convergence and extension of the Xenopus organiser., Dev Suppl 1992  
Most Recent Nanoscale electrostatic gating of molecular transport through nuclear pore complexes as probed by scanning electrochemical microscopy., Chem Sci 2019              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 5 terms 4 terms
PANTHER mib1
KEGG Pathways K10645 K10645 K10645
KOG [R] Uncharacterized conserved protein, contains ZZ-type Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks mib1
ORFs mib1.L ORF1
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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