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Summary Expression Gene Literature (9) GO Terms (10) Nucleotides (129) Proteins (36) Interactants (95) Wiki
XB-GENEPAGE-1001610
Gene Symbol:
neil3

Gene Name:
nei-like DNA glycosylase 3

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA topoisomerase III alpha

Protein Function :
DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA) (PubMed:30842657). Mediates interstrand cross...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1001611 XB-GENE-1001617 XB-GENE-17342803
Gene Symbol neil3 neil3.L neil3.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549955
100380996
108706496
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine neil3 neil3.L neil3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards NEIL3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Neil3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Neil3 Ensembl
zebrafish
ZFIN, AGR neil3 ZFIN Ensembl
chicken
GEISHA NEIL3 Ensembl
fruit fly
Publications
First Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation., Nat Struct Mol Biol 2016                  
Most Recent A non-canonical role for the DNA glycosylase NEIL3 in suppressing APE1 endonuclease-mediated ssDNA damage., J Biol Chem 2020  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 8 terms 0 term
PANTHER neil3
KEGG Pathways K10569 K10569
KOG [L] DNA topoisomerase III alpha
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks neil3
Morpholinos neil3 MO1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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