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Summary Expression Gene Literature (7) GO Terms (3) Nucleotides (808) Proteins (42) Interactants (748) Wiki
Gene Symbol:

Gene Name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

14-3-3 protein beta/alpha , 14-3-3 beta , 14-3-3beta , ywhab-a , ywhab-b ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction, kinase inhibitor

Protein Function :
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or ph...[+]

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External Links:
Xenbase Gene ID XB-GENE-1006026 XB-GENE-6254183 XB-GENE-1006032
Gene Symbol ywhab ywhab.L ywhab.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496529
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ywhab ywhab.L ywhab.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen ttpa010k20      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards YWHAB OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Ywhab MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Ywhab Ensembl
ZFIN, AGR ZFIN, AGR ywhabb ywhaba ZFIN Ensembl
fruit fly
First Activation of Raf-1 by 14-3-3 proteins., Nature 1994  
Most Recent 14-3-3 targets keratin intermediate filaments to mechanically sensitive cell-cell contacts., Mol Biol Cell 2020                
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 3 terms 2 terms 2 terms
KEGG Pathways K16197 K16197 K16197
KOG [O] Multifunctional chaperone (14-3-3 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ywhab
Morpholinos ywhab MO1 , ywhab MO2 , ywhab MO3 ywhab MO1 , ywhab MO3 ywhab MO1 , ywhab MO3
ORFs ywhab.L ORF1 ywhab.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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