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Summary Expression Gene Literature (1) GO Terms (15) Nucleotides (621) Proteins (54) Interactants (106) Wiki
XB-GENEPAGE-1007544
Gene Symbol:
psap

Gene Name:
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Prosaposin

Protein Function :
Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by...[+]



Interactants:
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Diseases: 


Disease Ontology:
atypical Gaucher's disease due to saposin c deficiency [+]

OMIM:
COMBINED SAPOSIN DEFICIENCY [+]

External Links:
 
Xenbase Gene ID XB-GENE-1007545 XB-GENE-1007550 XB-GENE-17343862
Gene Symbol psap psap.L psap.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 550039
447436
379512
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine psap psap.L psap.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards PSAP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Psap MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Psap Ensembl
zebrafish
ZFIN, AGR psap ZFIN Ensembl
chicken
GEISHA PSAP Ensembl
fruit fly
Publications
First Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Int J Dev Biol 2005                                    
Most Recent
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 7 terms 7 terms
PANTHER psap
KEGG Pathways K12382 K12382 K12382
KOG [IG] Prosaposin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks psap
ORFs psap.L ORF1 psap.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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