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Summary Expression Gene Literature (19) GO Terms (9) Nucleotides (380) Proteins (24) Interactants (79) Wiki
XB-GENEPAGE- 1008098

Gene Symbol: rad21

Gene Name: RAD21 cohesin complex component

Synonyms: xrad21 , hr21 , mcd1 , nxp1 , scc1 , nxp-1
Add Xenopus synonyms , Nomenclature history


Gene Function: Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1

Protein Function:
Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids aft...[+]


Interactants: YYY

OMIM Disease Associations: CORNELIA DE LANGE SYNDROME 4; CDLS4
 
Xenbase Gene ID XB-GENE-1008099 XB-GENE-17340158 XB-GENE-6078649
Gene Symbol rad21 rad21.L rad21.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein Refseq Swiss-Prot Swiss-Prot Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.46522 Xl.53864 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine rad21 rad21.L rad21.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RAD21 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Rad21 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN rad21a rad21b ZFIN Ensembl
chicken
GEISHA RAD21 Ensembl
fruit fly
worm
WORMBASE
Publications
First: NXP-1, a human protein related to Rad21/Scc1/Mcd1, is a component of the nuclear matrix. [Biochem Biophys Res Commun 2000]
Most recent: Initiation and maintenance of pluripotency gene expression in the absence of cohesin. [Genes Dev 2015]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 9 terms 1 terms
EC
PANTHER rad21
KEGG Pathways K06670 K06670
KOG [D] Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Antibody Rad21 Ab1 Rad21 Ab1 Rad21 Ab1
ORF Rad21 ORF1 rad21 ORF1
Affymetrix 1.0 Str.43835.1.A1_at [+] Xl.6046.1.S1_at Xl.23770.1.A1_at
Affymetrix 2.0 Xl2.53864.1.S1_a_at Xl2.46522.1.S1_at [+]

Symbol legend[+]

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