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Summary Expression Gene Literature (9) GO Terms (16) Nucleotides (172) Proteins (43) Interactants (261) Wiki
XB-GENEPAGE-1008433
Gene Symbol:
map3k1

Gene Name:
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

Synonyms:
mekk , mekk1 , mapkkk1 ( Add synonyms , Nomenclature history )

Gene Function:
MEKK and related serine/threonine protein kinases

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
46,XY sex reversal [+]

OMIM:
46,XY SEX REVERSAL 6; SRXY6

External Links:
 
Xenbase Gene ID XB-GENE-1008434 XB-GENE-17330816 XB-GENE-6487342
Gene Symbol map3k1 map3k1.L map3k1.S
Chromosome Chr1 chr1L Scaffold33
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100490504
108718321
108704427
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine map3k1 map3k1.L map3k1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MAP3K1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Map3k1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Map3k1 Ensembl
zebrafish
ZFIN, AGR map3k1 ZFIN Ensembl
chicken
GEISHA MAP3K1 Ensembl
fruit fly
worm
Publications
First Signaling pathways mediated by the mitogen-activated protein (MAP) kinase kinase/MAP kinase cascade., J Leukoc Biol 1994  
Most Recent Understanding MAPK Signaling Pathways in Apoptosis., Int J Mol Sci 2020            
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 3 terms 0 term
PANTHER map3k1
KEGG Pathways K20683 K04416
KOG [T] MEKK and related serine/threonine protein kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks map3k1
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

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