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Summary Expression Gene Literature (16) GO Terms (9) Nucleotides (386) Proteins (40) Interactants (190) Wiki
XB-GENEPAGE-1008579
Gene Symbol: plp1

Gene Name: proteolipid protein 1

Synonyms: plp , pmd , hld1 , mmpl , spg2 , plp1-a , plp1-b ( Add synonyms , Nomenclature history )

Gene Function: Neuronal membrane glycoprotein/Myelin proteolipid protein

Protein Function :
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.


Interactants: Loading ...
Disease Ontology: hereditary spastic paraplegia 2 [+]

OMIM Diseases: PELIZAEUS-MERZBACHER DISEASE; PMD [+]

 
Xenbase Gene ID XB-GENE-1008580 XB-GENE-1008585 XB-GENE-6255820
Gene Symbol plp1 plp1.L plp1.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 613099
Entrez Gene: 398334
Entrez Gene: 379423
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine plp1 plp1.L plp1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PLP1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Plp1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR plp1a plp1b ZFIN Ensembl
chicken
GEISHA PLP1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression of adenylate cyclase-coupled osseous parathyroid hormone and parathyroid hormone-like peptide receptors in Xenopus oocytes., J Biol Chem 1991  
Most Recent Odorant receptors from Culex quinquefasciatus and Aedes aegypti sensitive to floral compounds., Insect Biochem Mol Biol 2019  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 2 terms 2 terms
PANTHER plp1
KEGG Pathways K17271 K17271 K17271
KOG [X] Neuronal membrane glycoprotein/Myelin proteolipid protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon Horizon
ORF plp1 ORF1 plp1.L ORF1 plp1.S ORF1
Affymetrix 1.0 Str.49508.2.A1_a_at [+] Xl.17740.2.A1_a_at [+] Xl.199.1.S1_s_at [+]
Affymetrix 2.0 Xl2.19992.1.S1_at Xl2.199.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.3


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