Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (30) GO Terms (7) Nucleotides (848) Proteins (52) Interactants (137) Wiki
XB-GENEPAGE-1009647
Gene Symbol:
cldn6.2

Gene Name:
claudin 6, gene 2

Synonyms:
cldn4L1 , Xcla , cldna , claudin A , XclnA ( Add synonyms , Nomenclature history )

Gene Function:
integral membrane protein, tight junction component

Protein Function :
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1009648 XB-GENE-1009651 XB-GENE-17339342
Gene Symbol cldn6.2 cldn6.2.L cldn6.2.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100493413
398409
398209
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cldn6.2 cldn6.2.L cldn6.2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CLDN6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cldn6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cldn6 Ensembl
zebrafish
chicken
fruit fly
worm
Publications
First Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis., Dev Biol 2001                  
Most Recent EphA7 is required for otic epithelial homeostasis by modulating Claudin6 in Xenopus., Biochem Biophys Res Commun 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 4 terms 4 terms
PANTHER cldn6.2
KEGG Pathways K06087 K06087 K06087
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cldn6.2
Antibodies cldn6 Ab1 cldn6 Ab1 cldn6 Ab1
Morpholinos cldn6.2 MO1 cldn6.2 MO1 cldn6.2 MO1
ORFs cldn6.2.L ORF1 cla ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list