Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (85) GO Terms (50) Nucleotides (126) Proteins (30) Interactants (156) Wiki
XB-GENEPAGE-1010260
Gene Symbol:
cdk5

Gene Name:
cyclin-dependent kinase 5

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
early-expressed neuronal cyclin-dependent kinase

Protein Function :
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cel...[+]



Interactants:
Loading ...

Diseases: 


OMIM:
LISSENCEPHALY 7 WITH CEREBELLAR HYPOPLASIA; LIS7

External Links:
 
Xenbase Gene ID XB-GENE-1010261 XB-GENE-6254177 XB-GENE-17337284
Gene Symbol cdk5 cdk5.L cdk5.S
Chromosome Chr6 Scaffold42
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 780236
399296
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdk5 cdk5.L cdk5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CDK5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdk5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdk5 Ensembl
zebrafish
ZFIN, AGR cdk5 ZFIN Ensembl
chicken
GEISHA CDK5 Ensembl
fruit fly
FLYBASE Cdk5 Ensembl
worm
Publications
First Inhibition of cyclin-dependent kinases by purine analogues., Eur J Biochem 1994  
Most Recent Expression variation and covariation impair analog and enable binary signaling control., Mol Syst Biol 2018                              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 26 terms 28 terms 0 term
PANTHER cdk5
KEGG Pathways K02090 K02090
KOG [UT] Cyclin-dependent kinase CDK5
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdk5
Antibodies Cdk1 Ab2 Cdk1 Ab2 Cdk1 Ab2
ORFs cdk5 ORF2 , cdk5 ORF1 cdk5.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list