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Summary Expression Gene Literature (8) GO Terms (18) Nucleotides (114) Proteins (36) Interactants (46) Wiki
XB-GENEPAGE-1012053
Gene Symbol:
apex2

Gene Name:
apurinic/apyrimidinic endodeoxyribonuclease 2

Synonyms:
ape2 , xth2 , apexl2 ( Add synonyms , Nomenclature history )

Gene Function:
DNA repair

Protein Function :
Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate a...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1012054 XB-GENE-1012061 XB-GENE-17335121
Gene Symbol apex2 apex2.L apex2.S
Chromosome Chr8 Scaffold50
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 448512
446614
mRNA RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine apex2 apex2.L apex2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards APEX2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Apex2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Apex2 Ensembl
zebrafish
ZFIN, AGR apex2 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Subtraction scanning acoustic microscopy reveals motility domains in cells in vitro., Cell Motil Cytoskeleton 1994  
Most Recent A non-canonical role for the DNA glycosylase NEIL3 in suppressing APE1 endonuclease-mediated ssDNA damage., J Biol Chem 2020  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 9 terms 0 term
PANTHER apex2
KEGG Pathways K10772 K10772
KOG [L] Apurinic/apyrimidinic endonuclease and related enzymes
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks apex2
ORFs apex2 ORF1 apex2.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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