Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (7) Nucleotides (53) Proteins (30) Interactants (7) Wiki
XB-GENEPAGE-1012637
Gene Symbol:
grk1

Gene Name:
G protein-coupled receptor kinase 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
G protein-coupled receptor kinase

Protein Function :
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Oguchi disease-1 [+]

OMIM:
OGUCHI DISEASE 1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-1012638 XB-GENE-17340986 XB-GENE-1012639
Gene Symbol grk1 grk1.L grk1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100486335
443726
733223
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine grk1 grk1.L grk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GRK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Grk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Grk1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR grk1b grk1a ZFIN Ensembl
chicken
GEISHA GRK1 Ensembl
fruit fly
worm
Publications
First Phosphorylation of GRK7 by PKA in cone photoreceptor cells is regulated by light., J Neurochem 2008  
Most Recent An intrinsic compartmentalization code for peripheral membrane proteins in photoreceptor neurons., J Cell Biol 2019                        
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 7 terms 7 terms
PANTHER grk1
KEGG Pathways K00909 K00909
KOG [T] G protein-coupled receptor kinase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks grk1
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info