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Summary Expression Gene Literature (81) GO Terms (16) Nucleotides (409) Proteins (37) Interactants (289) Wiki
XB-GENEPAGE-1014887
Gene Symbol:
cdt1

Gene Name:
chromatin licensing and DNA replication factor 1

Synonyms:
xcdt1 , dup , ris2 ( Add synonyms , Nomenclature history )

Gene Function:
DNA replication

Protein Function :
DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with cdc6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-re...[+]



Interactants:
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Diseases: 


Disease Ontology:
Meier-Gorlin syndrome

OMIM:
MEIER-GORLIN SYNDROME 4; MGORS4

External Links:
1/3
 
Xenbase Gene ID XB-GENE-1014888 XB-GENE-1014892 XB-GENE-17344152
Gene Symbol cdt1 cdt1.L cdt1.S
Chromosome Chr4 Scaffold51 chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100379812
398024
108715404
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdt1 cdt1.L cdt1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CDT1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdt1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdt1 Ensembl
zebrafish
ZFIN, AGR cdt1 ZFIN Ensembl
chicken
GEISHA CDT1 Ensembl
fruit fly
Publications
First Novel angiotensin II antagonists distinguish amphibian from mammalian angiotensin II receptors expressed in Xenopus laevis oocytes., Mol Pharmacol 1991  
Most Recent MCM interference during licensing of DNA replication in Xenopus egg extracts-Possible Role of a C-terminal region of MCM3., Cell Cycle 2018  
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 4 terms 0 term
PANTHER cdt1
KEGG Pathways K10727 K10727
KOG [L] DNA replication factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdt1
ORFs cdt1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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