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Summary Expression Gene Literature (42) GO Terms (10) Nucleotides (269) Proteins (31) Interactants (527) Wiki
XB-GENEPAGE- 1015802

Gene Symbol: epha4

Gene Name: EPH receptor A4

Synonyms: sek , hek8 , tyr01 , rtk1 , XEpha4 , sek-1 , Pag , Pagliaccio , eph-a4 , epha4-a , epha4-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Tyrosine kinase, EPH (ephrin) receptor family

Protein Function:
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway ...[+]


Interactants: YYY

OMIM Disease Associations:
1/5
 
Xenbase Gene ID XB-GENE-1015803 XB-GENE-1015806 XB-GENE-6253098
Gene Symbol epha4 epha4.L epha4.S
Chromosome scaffold_9 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.57320 [+] Xl.13 Xl.57159
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 21 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine epha4 epha4.L epha4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EPHA4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Epha4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN epha4a epha4b ZFIN Ensembl
chicken
GEISHA EPHA4 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Expression and segregation of nucleoplasmin during development in Xenopus. [Development 1988]
Most recent: Sorting at embryonic boundaries requires high heterotypic interfacial tension. [Nat Commun 2017]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 3 terms 9 terms
EC now EC:2.7.10.1 and EC:2.7.10.2
PANTHER epha4
KEGG Pathways K05105 K05105 K05105
KOG [T] Tyrosine kinase, EPH (ephrin) receptor family
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino epha4 MO1 , epha4 MO2 epha4 MO1 , epha4 MO2 epha4 MO1 , epha4 MO2
ORF epha4 ORF1
Affymetrix 1.0 StrJgi.2833.1.S1_s_at [+] Xl.13.1.S1_at [+]
Affymetrix 2.0 Xl2.13.1.S1_at [+]

Symbol legend[+]

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