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Summary Expression Gene Literature (244) GO Terms (21) Nucleotides (308) Proteins (51) Interactants (1026) Wiki
XB-GENEPAGE-1015802
Gene Symbol:
epha4

Gene Name:
EPH receptor A4

Synonyms:
sek , hek8 , tyr01 , rtk1 , XEpha4 , sek-1 , Pag , Pagliaccio , eph-a4 , epha4-a , epha4-b ( Add synonyms , Nomenclature history )

Gene Function:
Tyrosine kinase, EPH (ephrin) receptor family

Protein Function :
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway ...[+]


InterPro :
Kinase-like dom sf , Tyr kinase ephrin rcpt , Galactose-bd-like sf , Tyr-kin ephrin A/B rcpt-like [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-1015803 XB-GENE-1015806 XB-GENE-6253098
Gene Symbol epha4 epha4.L epha4.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216124
379148
779062
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine epha4 epha4.L epha4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EPHA4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Epha4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Epha4 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR epha4a epha4b ZFIN Ensembl
chicken
GEISHA EPHA4 Ensembl
fruit fly
worm
Publications
First Expression and segregation of nucleoplasmin during development in Xenopus., Development 1988                      
Most Recent Tissue segregation in the early vertebrate embryo., Semin Cell Dev Biol 2020  
All View All Papers 8 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 10 terms 8 terms
PANTHER epha4
KEGG Pathways K05105 K05105 K05105
KOG [T] Tyrosine kinase, EPH (ephrin) receptor family
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks epha4
Morpholinos epha4 MO1 , epha4 MO2 epha4 MO1 , epha4 MO2 epha4 MO1 , epha4 MO2
ORFs epha4.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list