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Summary Expression Gene Literature (131) GO Terms (15) Nucleotides (375) Proteins (47) Interactants (1184) Wiki
XB-GENEPAGE-1018553
Gene Symbol: fgfr1

Gene Name: fibroblast growth factor receptor 1

Synonyms: X1FGFR , XFGFR-1 , flt2 , flt-2 , xfgfr1 , cek , flg , ogd , flt2 , kal2 , bfgfr , fgfr-1 , fgfr1-a , fgfr1-b ( Add synonyms , Nomenclature history )

Gene Function: receptor tyrosine kinase

Protein Function :
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and ...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: hypogonadotropic hypogonadism 2 with or without anosmia [+]

OMIM: JACKSON-WEISS SYNDROME; JWS [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/2
 
Xenbase Gene ID XB-GENE-1018554 XB-GENE-1018562 XB-GENE-6254218
Gene Symbol fgfr1 fgfr1.L fgfr1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548648
399444
394418
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq TrEMBL TrEMBL RefSeq TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine fgfr1 fgfr1.L fgfr1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu076b03      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FGFR1 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Fgfr1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR fgfr1b fgfr1a ZFIN Ensembl
chicken
GEISHA FGFR1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos., Cell 1991  
Most Recent A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development., Biol Cell 2020  
All View All Papers 19 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 4 terms 8 terms
PANTHER fgfr1
KEGG Pathways K04362 K04362 K04362
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fgfr1
Antibodies Fgfr1 Ab2 Fgfr1 Ab2 Fgfr1 Ab2
Morpholinos fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4
ORFs fgfr1 ORF1 fgfr1.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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