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Summary Expression Gene Literature (115) GO Terms (8) Nucleotides (357) Proteins (28) Interactants (700) Wiki
XB-GENEPAGE- 1018553

Gene Symbol: fgfr1

Gene Name: fibroblast growth factor receptor 1

Synonyms: X1FGFR , XFGFR-1 , flt2 , flt-2 , xfgfr1 , cek , flg , ogd , flt2 , kal2 , bfgfr , fgfr-1 , fgfr1-a , fgfr1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: receptor tyrosine kinase

Protein Function:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and ...[+]


Interactants: Loading ...

OMIM Disease Associations: JACKSON-WEISS SYNDROME; JWS [+]
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Xenbase Gene ID XB-GENE-1018554 XB-GENE-1018562 XB-GENE-6254218
Gene Symbol fgfr1 fgfr1.L fgfr1.S
Chromosome scaffold_3 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.48478 Xl.2751 Xl.34918
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 42 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fgfr1 fgfr1.L fgfr1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu076b03      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FGFR1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Fgfr1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN fgfr1b fgfr1a ZFIN Ensembl
chicken
GEISHA FGFR1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. [Cell 1991]
Most recent: A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates. [PLoS Biol 2017]
View All Papers 19 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 8 terms
EC now EC:2.7.10.1 and EC:2.7.10.2
PANTHER fgfr1
KEGG Pathways K04362 K04362 K04362
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Fgfr1 Ab2 Fgfr1 Ab2 Fgfr1 Ab2
Morpholino fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4 fgfr1 MO1 , fgfr1 MO2 , fgfr1 MO3 , fgfr1 MO4
ORF fgfr1 ORF1
Affymetrix 1.0 Str.26699.1.S1_at Xl.2751.1.S1_at Xl.6480.2.S1_a_at
Affymetrix 2.0 Xl2.2751.1.S1_at Xl2.34918.1.S1_at [+]

Symbol legend[+]

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