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Summary Expression Gene Literature (933) GO Terms (22) Nucleotides (1730) Proteins (59) Interactants (701) Wiki
XB-GENEPAGE-1019570
Gene Symbol:
npm1

Gene Name:
nucleophosmin (nucleolar phosphoprotein B23, numatrin)

Synonyms:
nucleophosmin , B23 , numatrin , nucleoplasmin , npm ( Add synonyms , Nomenclature history )

Gene Function:
nucleic acid binding

Protein Function :
Acts as a chaperonin for the core histones H3, H2B and H4. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. It may function in the assembly and/or transpor...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
dyskeratosis congenita [+]

OMIM:
LEUKEMIA, ACUTE MYELOID; AML

External Links:
 
Xenbase Gene ID XB-GENE-1019571 XB-GENE-17340890 XB-GENE-1019578
Gene Symbol npm1 npm1.L npm1.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394478
379450
379194
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine npm1 npm1.L npm1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NPM1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Npm1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Npm1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR npm1a npm1b ZFIN Ensembl
chicken
GEISHA NPM1 Ensembl
fruit fly
worm
Publications
First Assembly of nucleosomes: the reaction involving X. laevis nucleoplasmin., Cell 1980  
Most Recent Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site., PLoS One 2020                                              
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 4 terms 9 terms
PANTHER npm1
KEGG Pathways K11276 K11276 K11276
KOG [AJ] Polyadenylate-binding protein (RRM superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks npm1
Antibodies Npm1 Ab1 Npm1 Ab1
ORFs npm1 ORF1 MGC64305 ORF1 npm1.L ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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