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XB-GENEPAGE-1031984
Gene Symbol:
tcf7l1
Gene Name: transcription factor 7 like 1
Synonyms:
tcf3c
,
tcf3d
,
XTCF-3
,
xtcf3
,
tcf7l1-a
,
tcf7l1-b
( Gene Function: high mobility group transcription factor Protein Function
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Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early i...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID
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XB-GENE-1031985 | XB-GENE-6252329 | XB-GENE-1031992 | |||||
Gene Symbol | tcf7l1 | tcf7l1.L | tcf7l1.S | Chromosome | Chr3 | chr3L | chr3S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
448107
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397863
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394281
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | tcf7l1 | tcf7l1.L | tcf7l1.S | |||||
Orthology ![]() |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos., Cell 1996 ![]() |
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Most Recent |
Integration of Wnt and FGF signaling in the Xenopus gastrula at TCF and Ets binding sites shows the importance of short-range repression by TCF in patterning the marginal zone., Development 2019 ![]() |
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All | View All Papers 23 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 19 terms | 12 terms | 7 terms | |||||
PANTHER | tcf7l1 | |||||||
KEGG Pathways | K04490 | K04490 | K04490 | |||||
KOG |
[K] Transcription factor TCF-4
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | tcf7l1 | |||||||
Morpholinos | tcf7l1 MO1 , tcf7l1 MO2 , tcf7l1 MO3 , tcf7l1 MO4 | tcf7l1 MO1 , tcf7l1 MO2 , tcf7l1 MO4 , tcf7l1 MO3 | ||||||
ORFs | tcf7l1.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
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