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Summary Expression Gene Literature (97) GO Terms (14) Nucleotides (293) Proteins (28) Interactants (632) Wiki
XB-GENEPAGE- 1031984

Gene Symbol: tcf7l1

Gene Name: transcription factor 7 like 1

Synonyms: tcf3c , tcf3d , XTCF-3 , xtcf3 , tcf7l1-a , tcf7l1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: high mobility group transcription factor

Protein Function:
Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early i...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-1031985 XB-GENE-6252329 XB-GENE-1031992
Gene Symbol tcf7l1 tcf7l1.L tcf7l1.S
Chromosome scaffold_3 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.11534 [+] Xl.1100 Xl.85456 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 4 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tcf7l1 tcf7l1.L tcf7l1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TCF7L1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tcf7l1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN tcf7l1b tcf7l1a ZFIN Ensembl
chicken
GEISHA TCF7L1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. [Cell 1996]
Most recent: High variability of expression profiles of homeologous genes for Wnt, Hh, Notch, and Hippo signaling pathways in Xenopus laevis. [Dev Biol 2017]
View All Papers 23 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 13 terms 8 terms
EC
PANTHER tcf7l1
KEGG Pathways K04490 K04490 K04490
KOG [K] Transcription factor TCF-4
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino tcf7l1 MO1 , tcf7l1 MO2 , tcf7l1 MO3 , tcf7l1 MO4 tcf7l1 MO1 , tcf7l1 MO2 , tcf7l1 MO3 , tcf7l1 MO4 tcf7l1 MO1 , tcf7l1 MO2 , tcf7l1 MO3 , tcf7l1 MO4
ORF tcf7l1 ORF1
Affymetrix 1.0 Str.24440.1.S2_at [+] Xl.46.1.S1_at [+]
Affymetrix 2.0 Xl2.46.2.S1_a_at [+]

Symbol legend[+]

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