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XB-GENEPAGE-1032966
Gene Symbol:
ascl1
Gene Name: achaete-scute family bHLH transcription factor 1
Synonyms:
ash1
,
Xash1
,
Mash1
( Gene Function: HAND2 type transcription factor Protein Function
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Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. D...[+]
Interactants:
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Diseases: Disease Ontology:
congenital central hypoventilation syndrome
OMIM:
CENTRAL HYPOVENTILATION SYNDROME, CONGENITAL; CCHS
External Links:
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Xenbase Gene ID
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XB-GENE-1032967 | XB-GENE-1032969 | XB-GENE-17340658 | |||||
Gene Symbol | ascl1 | ascl1.L | ascl1.S | Chromosome | Chr3 | chr3L | chr3S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100490701
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378517
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444423
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | ascl1 | ascl1.L | ascl1.S | |||||
Orthology ![]() |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS., Mech Dev 1993 |
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Most Recent |
Cellular response to spinal cord injury in regenerative and non-regenerative stages in Xenopus laevis., Neural Dev 2021 ![]() |
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All | View All Papers 6 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 0 term | 12 terms | 4 terms | |||||
PANTHER | ascl1 | |||||||
KEGG Pathways | K09067 | K09067 | ||||||
KOG |
[K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | ascl1 | |||||||
Mutants | Xtr.ascl1emHorb | |||||||
Morpholinos | ascl1 MO1 | ascl1 MO2 | ||||||
ORFs | ascl1.S ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



