Gene Symbol: ascl1 [provisional] Gene Name: achaete-scute complex homolog 1 [provisional] Synonyms: ash1, Xash1, Mash1 Add Xenopus synonyms Gene Function: HAND2 type transcription factor Interactants: neurod1(9) , atoh7(6) , neurog1(6) , notch1(5) , pax6(5) , neurod4(4) , neurog2(4) View All	1/2

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002944602|PREDICTED: Xenopus (Silurana) tropicalis achaete-scute homolog 1-like (LOC100490701), partial mRNA CGCTCGTCCTCCCCGGAGCTGATGAGGTGCAAGAGGCGCCTGAACTTCACCGGCTTCGGCTACAGCCTCCCGCAGCAGCAACCGGCCGCCGTGGCCCGGAGGAACGAGAGGGAGAGGAACCGGGTCAAGCTGGTCAATTTGGGTTTTGCCACTCTGAGGGAACACGTCCCCAACGGTGCGGCCAACAAGAAGATGAGCAAAGTGGAAACGCTGCGATCTGCAGTAGAGTACATCAGGGCGCTGCAACAGTTGCTGGACGAACACGACGCTGTCAGTGCAGCTTTCCAGTCCGGCGTTCTTTCCCCCACCATCTCCCCCAACTATTCCCACGATATGAACTCTATGGCGGGGTCCCCCGTCTCCTCTTACTCATCAGATGAAGGCTCGTATGATCCGCTGAGCCCGGAGGAGCAGGAGCTGCTCGACTTCACCACTTGGTTCTGA	Refseq >NM_001085778|Xenopus laevis achaete-scute complex homolog 1 (ascl1), mRNA CAGCATTGAGCGCACAGAGCTAGAGCCAGGGAACGTGCGGGGCCGCTCCTGTCACTTTGCAACAGCAGCATCATCCTCCTCCTCACCCGCACAGCCAGAGCAACACGCGAACGGCACGAGCCCCACTGCCTCCTCAGCTCACCTCCTCCTGCCCAGCAGCCTGTCAGCATGGACAACTGCGTCGCTGCCAAGATCATGGACAGCAACTTATCCAGCCAGCAGCAGCATTTCCTACAGCCCCATTGCTTCTTCCCGCAGAACGTGCAGCAGCTGAGCCCGGCGGAGGAGCAACAAGCGTCCAAAGCCAAGCCCATCAAGAGGCAACGCTCGGCCTCCCCGGAGCTGATGAGGTGCAAGAGGCGGCTGAACTTCAATGGCTTCGGCTACAGCCTCCCGCAGCAGCAACCGGCCGCCGTGGCCCGGAGGAACGAGAGGGAAAGGAACCGGGTCAAGCTGGTCAATCTCGGCTTTGCCACCCTCAGGGAGCACGTCCCCAACGGTGCGGCCAACAAGAAGATGAGCAAAGTGGAGACGCTGCGATCGGCAGTCGAGTACATCAGGGCGCTGCAACAGCTGCTGGACGAACATGACGCTGTCAGCGCCGCTTTCCAGTCCGGGGTTCTTTCCCCCACCATCTCCCCCAACTATTCCCACGATATGAACTCTATGGCGGGCTCCCCCGTCTCCTCGTACTCCTCAGATGAAGGCTCCTATGATCCGCTGAGCCCGGAGGAGCAAGAACTTCTCGACTTCACCACTTGGTTCTGAGATGCGGAGTAGCAGGCTGTTTGCCTCCCTGCTTGGATAACAAAGTGAAGCACACAGGAGCAGTTGGTCCCTCCAAGAACACTGAAGCACTACATTTGCACTCCAGTACGATTCACTGGATGGATAGAGACATAATGCCGTGGGGCTCGTGGGTGGTGAAGCACACAGACACCATCCCACTCACGCATGGAAGAGACGTGGTCCGTATGAACAACCCGGGGCTACCCCATATAAAACCAAGCCCTTATTGACTATACCCTCCTTCTTTTATCGATGGAGGCCGTTCCCGGATCAGAATTTGTGGCGTGTTTATCCAAACTATGCTGTTATTCAAAGAAACCCCCCTCCCCTTCAGACTCTACCCCCTTTTTTTTTTTTGTACCACTTTCATCCTTAAATGCTTCCAATCTTTTGTGAAATTTTTTTTTATTATAAGAAATATTTCTATCTATCCCAACTGTTTTGGGATATATTAAGCTATTTTTGTACATAAGAGAGAAATTTATAGAAGTTTTGTACAAATGGTATGAAATATGTATATCTTGATACATTATTATGTAATGCTTATTACCTCTGCATATTTAGACTTGTAGTCTATAACCTTGCAACTGCAATTTTGTATGTGGTTTTGTAAAGGACACTCCTTTTAAGGTGGGGTTGGAATTCCTACAGATGTACTTTAGCACCAACGTGTCTTACTTTATAGAAACTTTGTTAATGCATTAATTGTGTTATTAAACAATGTTCACAGTGAACAAAGTTTATGCAGCTATTGTCCAAACGCAAAATAGTGGTCCACTGTATCTATGCTGCTTTCGGAACTCTATATACCACTGCCTTTTCTTACTGTTTTTAATACAAACTTACAAATGTCCTGCATAACTATGTTTTTTTACACAATAGTTTCATAATAAAACATTTTTATATAG
Protein		NCBI Protein >XP_002944648|PREDICTED: achaete-scute homolog 1-like, partial [Xenopus (Silurana) tropicalis] RSSSPELMRCKRRLNFTGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISPNYSHDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTTWF	Refseq >NP_001079247|achaete-scute homolog 1 [Xenopus laevis] MDNCVAAKIMDSNLSSQQQHFLQPHCFFPQNVQQLSPAEEQQASKAKPIKRQRSASPELMRCKRRLNFNGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQSGVLSPTISPNYSHDMNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTTWF UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.44710	Xl.450
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		5 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	ASCL1	OMIM:209880
mouse		MGI	Ascl1	All(8) Targeted, knock Out(2) Targeted, other(4)
zebrafish		ZFIN ZFIN	ascl1b ascl1a	4 Lines(s)

Publications
First:		XASH1, a Xenopus homolog of achaete-scute: a proneural gene in anterior regions of the vertebrate CNS. [Mech Dev 1993]
Most recent:		Using myc genes to search for stem cells in the ciliary margin of the Xenopus retina. [Dev Neurobiol 2012]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.23679.1.A1_at [+] Str.44710.1.A1_at	Xl.450.1.S1_at
Affymetrix 2.0			Xl2.450.1.S1_at

Symbol legend[+]

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