Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (8) GO Terms (36) Nucleotides (93) Proteins (35) Interactants (158) Wiki
XB-GENEPAGE-1033014
Gene Symbol:
zic4

Gene Name:
Zic family member 4

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
May bind to DNA. Induces neural and neural crest differentiation. Does not induce anterior neural tissue.


InterPro :
Peptidase S1 PA , Peptidase S1C , PDZ sf , Small GTPase Rho [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/4
 
Xenbase Gene ID XB-GENE-1033015 XB-GENE-1033019 XB-GENE-17343672
Gene Symbol zic4 zic4.L zic4.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100493609
100158334
108718145
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine zic4 zic4.L zic4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ZIC4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Zic4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Zic4 Ensembl
zebrafish
ZFIN, AGR zic4 ZFIN Ensembl
chicken
GEISHA ZIC4 Ensembl
fruit fly
Publications
First Xenopus Zic4: conservation and diversification of expression profiles and protein function among the Xenopus Zic family., Dev Dyn 2006                                  
Most Recent Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis., Proc Natl Acad Sci U S A 2018                      
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 33 terms 5 terms 0 term
PANTHER zic4
KEGG Pathways K07863 K09225
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks zic4
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info