Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (14) Nucleotides (114) Proteins (27) Interactants (432) Wiki
XB-GENEPAGE- 1216150

Gene Symbol: lzts2

Gene Name: leucine zipper, putative tumor suppressor 2

Synonyms: LAPSER1
Add Xenopus synonyms , Nomenclature history


Gene Function: Myosin class II heavy chain

Protein Function:
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt sign...[+]


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-1216151 XB-GENE-17336246 XB-GENE-6253849
Gene Symbol lzts2 lzts2.L lzts2.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide NCBI Nucleotide
Protein Refseq Swiss-Prot NCBI Protein TrEMBL NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.10158 Xl.49480 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 5 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lzts2 lzts2.L lzts2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tegg129e23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LZTS2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lzts2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN lzts2b lzts2a ZFIN Ensembl
chicken
GEISHA LZTS2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. [PLoS Genet 2006]
Most recent: The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development. [J Biol Chem 2011]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 10 terms 0 term
EC
PANTHER lzts2
KEGG Pathways
KOG [Z] Myosin class II heavy chain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino lzts2 MO1 lzts2 MO1 lzts2 MO1
ORF lzts2 ORF1
Affymetrix 1.0 Str.10158.1.S1_at
Affymetrix 2.0 Xl2.49480.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556