Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (12) Nucleotides (139) Proteins (40) Interactants (626) Wiki
XB-GENEPAGE-1216150
Gene Symbol:
lzts2

Gene Name:
leucine zipper, putative tumor suppressor 2

Synonyms:
LAPSER1 ( Add synonyms , Nomenclature history )

Gene Function:
Myosin class II heavy chain

Protein Function :
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt sign...[+]


InterPro :
LZTS2 , Ig-like fold , Ig-like dom sf

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1216151 XB-GENE-17336246 XB-GENE-6253849
Gene Symbol lzts2 lzts2.L lzts2.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448373
108696150
108697425
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lzts2 lzts2.L lzts2.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tegg129e23      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards LZTS2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lzts2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lzts2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR lzts2b lzts2a ZFIN Ensembl
chicken
GEISHA LZTS2 Ensembl
fruit fly
Publications
First Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., PLoS Genet 2006                                      
Most Recent The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development., J Biol Chem 2011  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 11 terms 0 term
PANTHER lzts2
KEGG Pathways
KOG [Z] Myosin class II heavy chain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lzts2
Morpholinos lzts2 MO1 lzts2 MO1
ORFs lzts2 ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info