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XB-GENEPAGE-
1216150
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Gene Symbol: lzts2
Gene Name: leucine zipper, putative tumor suppressor 2 Synonyms: LAPSER1 Add Xenopus synonyms , Nomenclature history Gene Function: Myosin class II heavy chain Protein Function  :
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt sign...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: |
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| Xenbase Gene ID | XB-GENE-1216151 | XB-GENE-17336246 | XB-GENE-6253849 | ||||||||||
| Gene Symbol | lzts2 | lzts2.L | lzts2.S | ||||||||||
| Chromosome | Chr07 | chr7L | chr7S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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NCBI Nucleotide
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NCBI Nucleotide
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| Protein
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Refseq
Swiss-Prot
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NCBI Protein
TrEMBL
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NCBI Protein
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.10158 | Xl.49480 [+] | |||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 5 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | lzts2 | lzts2.L | lzts2.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | tegg129e23 | ||||||||||||
| Orthology |
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| worm |
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| Publications | |||||||||||||
| First: |
Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides. [PLoS Genet 2006]
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| Most recent: | The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development. [J Biol Chem 2011] | ||||||||||||
| View All Papers 1 paper(s) referencing morpholinos | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 14 terms | 10 terms | 0 term | ||||||||||
| PANTHER | lzts2 | ||||||||||||
| KEGG Pathways | |||||||||||||
| KOG |
[Z] Myosin class II heavy chain
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
| Clones | |||||||||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | ||||||||||||
| Morpholino | lzts2 MO1 | lzts2 MO1 | lzts2 MO1 | ||||||||||
| ORF | lzts2 ORF1 | lzts2.S ORF1 | |||||||||||
| Affymetrix 1.0 | Str.10158.1.S1_at | ||||||||||||
| Affymetrix 2.0 | Xl2.49480.1.S1_at [+] | ||||||||||||
Symbol legend[+]
